Protein Alignment fkh and FOXF2

DIOPT Version :9

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001443.1
• Gene: FOXF2 / 2295
• HGNCID: 3810
• Length: 444
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 153/554 - (27%)
• Similarity: 214/554 - (38%)
• Gaps: 203/554 - (36%)

  Fly    39 GGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGG-----MSSVSPQAAATFSSSVLDSAA 98
            |||||               :||.|:.       .||.|     :.|..|.|||        :||
Human     5 GGPPP---------------APLRRAC-------SPVPGALQAALMSPPPAAAA--------AAA 39

  Fly    99 AVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAAS 163
            |....::|.|:|.|||..:|.:.|..|:                               |.|||.
Human    40 AAPETTSSSSSSSSASCASSSSSSNSAS-------------------------------APSAAC 73

  Fly   164 MSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPT 228
            .||.|  |..||...|:::..:|               .||.   .|||||||:||.||||::|:
Human    74 KSAGG--GGAGAGSGGAKKASSG---------------LRRP---EKPPYSYIALIVMAIQSSPS 118

  Fly   229 RMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNM 293
            :.|||||||||:...|||:|...|.|:||:||:||.|:||:|:|:...:||||.:||:.|.|..|
Human   119 KRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFM 183

  Fly   294 FENGCYLRRQKRFKDEKKEAIRQLH--------------------KSPSHSSLEATSPGKKDHED 338
            ||.|.:.||.:.|: .|.:|::.::                    ::|..:.|...|.|.....|
Human   184 FEEGSFRRRPRGFR-RKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQGGYGGLD 247

  Fly   339 -------------SH-HMHHHHHSRLDHHQHHKEAGGASI--------AGVNVLSAA-------H 374
                         || |.|||||    ||..|......|.        ||...:.||       :
Human   248 MMPAGYDAGAGAPSHAHPHHHHH----HHVPHMSPNPGSTYMASCPVPAGPGGVGAAGGGGGGDY 308

  Fly   375 SKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMAN--RCH-PSLITDYHSS-- 434
            ..|:              |..|  ||:              |..||:  .|| |......|.|
Human   309 GPDS--------------SSSP--VPS--------------SPAMASAIECHSPYTSPAAHWSSP 343

  Fly   435 -MHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQ-YAGYNALSPLTNSHAALGQDSY-- 495
             ..|..::|...||||:|.:...|     .:.:..|.:.| |...||...|     ::|...|
Human   344 GASPYLKQPPALTPSSNPAASAGL-----HSSMSSYSLEQSYLHQNAREDL-----SVGLPRYQH 398

  Fly   496 --------------YQSLGYHAPAGTTSLXHHQY 515
                          :..:....|:.:.|..||.:
Human   399 HSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHH 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	16/88 (18%)
		FH	210..298	CDD:214627	51/87 (59%)
FOXF2	NP_001443.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..98		29/121 (24%)
		FH	100..188	CDD:214627	51/87 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..323		22/100 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..367		9/28 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910