Protein Alignment fkh and FOXF1

DIOPT Version :9

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001442.2
• Gene: FOXF1 / 2294
• HGNCID: 3809
• Length: 379
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 141/615 - (22%)
• Similarity: 205/615 - (33%)
• Gaps: 261/615 - (42%)

  Fly    11 SSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPV 75
            ||||....      ||.|||||||||||....|
Human     2 SSAPEKQQ------PPHGGGGGGGGGGGAAMDP-------------------------------- 28

  Fly    76 GGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSS 140
                                         ||...|.:...||
Human    29 -----------------------------ASSGPSKAKKTNA----------------------- 41

  Fly   141 MSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRS 205
                                                  |.|..|
Human    42 --------------------------------------GIRRPE--------------------- 47

  Fly   206 YTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVK 270
                |||||||:||.||||::||:.|||||||||:...|||:|.:.|.|:||:||:||.|:||:|
Human    48 ----KPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIK 108

  Fly   271 IPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKD 335
            :|:...:||||.:||:.|.|..|||.|.:.||.:.|: .|.:|::     |.:|.:....
Human   109 LPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFR-RKCQALK-----PMYSMMNGLG----- 162

  Fly   336 HEDSHHMHHHHHSRLDHHQHHKEAGGASI--------AGVNVLSAAHSKDAEALAMLHANAELCL 392
               .:|:.       |.:.....|||.|.        .|:.:::.....:.:.:|:        .
Human   163 ---FNHLP-------DTYGFQGSAGGLSCPPNSLALEGGLGMMNGHLPGNVDGMAL--------P 209

  Fly   393 SQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDY--HSSMHPLKQEPSGYTPSSHPFSIN 455
            |....|:|::..|.:            ...|..:...:|  |.|..|                .:
Human   210 SHSVPHLPSNGGHSY------------MGGCGGAAAGEYPHHDSSVP----------------AS 246

  Fly   456 RLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYY---QSLGYHAPAG---TTSLXHHQ 514
            .||||.:...::.:  :.|:|..|..| .::.|||...:.|   |.|....||.   :.||..|
Human   247 PLLPTGAGGVMEPH--AVYSGSAAAWP-PSASAALNSGASYIKQQPLSPCNPAANPLSGSLSTH- 307

  Fly   515 YPLAXGRAEQMLRSQQQQHL-QQQHQQHQQQQQQHQLHQQQQQMQQSAQQLTSASNTPATSAKAS 578
                         |.:|.:| |..|....:.|...:.|.|...|....:.:.
Human   308 -------------SLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVF------------- 346

  Fly   579 GKAGSASASGSGSGSGSGSGSNYSQKLQQQ 608
                |.:|..|.|...:|.||.|.|::..|
Human   347 ----SFNAMASSSMHSAGGGSYYHQQVTYQ 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	3/88 (3%)
		FH	210..298	CDD:214627	52/87 (60%)
FOXF1	NP_001442.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		24/170 (14%)
		FH	48..136	CDD:214627	52/87 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910