DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and FOXD4L1

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_036316.1 Gene:FOXD4L1 / 200350 HGNCID:18521 Length:408 Species:Homo sapiens


Alignment Length:417 Identity:120/417 - (28%)
Similarity:151/417 - (36%) Gaps:148/417 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   209 AKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPR 273
            ||||||||:||||||..:|.:.||||.|..||...||:||:....|||||||:||.|||||||||
Human   106 AKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPR 170

  Fly   274 TPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHED 338
            .|..||||::|:|.|.|.:||:||.:|||:||||..:                  .:||.     
Human   171 EPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQ------------------LTPGA----- 212

  Fly   339 SHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVP--- 400
              |:.|.......|...|....|..:.            |.||              ||.||   
Human   213 --HLPHPFPLPAAHAALHNPRPGPLLG------------APAL--------------PQPVPGAY 249

  Fly   401 ------------THHHHQHHQLQQEELSAMM----------ANRCHPSLITDYHSSMHP------ 437
                        .|.|...:.|    |||..          |:...|..:.....|:.|      
Human   250 PNTAPGRRPYALLHPHPPRYLL----LSAPAYAGAPKKAEGADLATPGTLPVLQPSLGPQPWEEG 310

  Fly   438 --LKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYYQSLG 500
              |...|.|...|   |||..::.....|..        ....:|||...|:..|.|.....|..
Human   311 KGLASPPGGGCIS---FSIESIMQGVRGAGT--------GAAQSLSPTAWSYCPLLQRPSSLSDN 364

  Fly   501 YHAPAGTTSLXHHQYPLAXGRAEQMLRSQQQQHLQQQHQQHQQQQQQHQLHQQQQQMQQSAQQLT 565
            :.|.|..:.          |...|.|||.|.:                                 
Human   365 FAATAAASG----------GGLRQRLRSHQGR--------------------------------- 386

  Fly   566 SASNTPATSAKASGKAGSASASGSGSG 592
            .|...|.      |:.|:|:.||.|.|
Human   387 GAGRAPV------GRVGAAAVSGGGRG 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 120/417 (29%)
FH 210..298 CDD:214627 55/87 (63%)
FOXD4L1NP_036316.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..54
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..104
Forkhead 107..193 CDD:278670 54/85 (64%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 385..408 9/62 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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