Protein Alignment fkh and unc-130

DIOPT Version :10

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_496411.1
• Gene: unc-130 / 174721
• WormBaseID: WBGene00006853
• Length: 333
• Species: Caenorhabditis elegans
• Alignment Length: 249
• Identity: 81/249 - (32%)
• Similarity: 117/249 - (46%)
• Gaps: 75/249 - (30%)

  Fly   197 DKPTTYRRSY------THAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQ 255
            |..:|.|:|.      :|||||||||:||.|:|.|:|.:.||||||.:||::.|.:|::....||
 Worm   108 DDDSTSRKSMSGHRKSSHAKPPYSYIALIAMSILNSPEKKLTLSEICEFIINKFEYYKEKFPAWQ 172

  Fly   256 NSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKS 320
            |||||:||.||||||:.|.|..||||::|.|.|:..:||:||.:|||:||:
 Worm   173 NSIRHNLSLNDCFVKVARGPGNPGKGNYWALDPNCEDMFDNGSFLRRRKRY-------------- 223

  Fly   321 PSHSSLEATSPGKKDHEDSHHMHHHH--------------HSRLDHHQHHKEAGGASIAGVNVLS 371
                        ||:.:..|.|..||              ..|:.|..            .|:..
 Worm   224 ------------KKNSDTYHEMMSHHPMPFPPFLPQGMPFPPRMMHPM------------ANIPM 264

  Fly   372 AAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHP 425
            ..|..:..|:..:.|          ..:|       ..:..::|.:|||:|..|
 Worm   265 LGHPMNPRAVPNMPA----------FFIP-------QNIDSQKLLSMMASRIMP 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:369872	4/17 (24%)
		FH_dFKH	210..307	CDD:410815	56/96 (58%)
unc-130	NP_496411.1	COG5025	<126..330	CDD:227358	76/231 (33%)
		FH_FOX	127..222	CDD:469596	54/94 (57%)