DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and Foxd2

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_032619.1 Gene:Foxd2 / 17301 MGIID:1347471 Length:492 Species:Mus musculus


Alignment Length:356 Identity:114/356 - (32%)
Similarity:142/356 - (39%) Gaps:118/356 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 SAPVSMASSGGGGPPSGGGGGGGG-GGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPV 75
            |:|.:::.........|||.|||. ....||..|.:..|:     |...|...:...:.......
Mouse    15 SSPAALSEPDADIDVVGGGSGGGELTARSGPRAPRDVLPH-----GHEPPPEEAEADVAEDEEES 74

  Fly    76 GGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSS 140
            ||.|...|:|.|                                  ..|||              
Mouse    75 GGCSDCEPRALA----------------------------------PRGAA-------------- 91

  Fly   141 MSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRS 205
               |:.|||                ..|:....||..||.   ..|.|:  |.:....|.     
Mouse    92 ---AAAGSP----------------GPGVQAARGATGPGP---GPGPPS--GGAATRSPL----- 127

  Fly   206 YTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVK 270
               .|||||||:||||||..:|.:.||||||.:||...||:||:....|||||||:||.||||||
Mouse   128 ---VKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVK 189

  Fly   271 IPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKD 335
            |||.|..||||::|||.|:|.:||:||.:|||:||||       ||....|              
Mouse   190 IPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFK-------RQPLPPP-------------- 233

  Fly   336 HEDSHHMHHHHHSRLDHHQHHKEAGGASIAG 366
                 |.|.|.|..|      ...|||:.||
Mouse   234 -----HPHPHPHPEL------LLRGGAAAAG 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 16/88 (18%)
FH 210..298 CDD:214627 57/87 (66%)
Foxd2NP_032619.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 13..125 35/186 (19%)
Forkhead 129..215 CDD:278670 56/85 (66%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 309..344
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 394..441
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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