DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and Foxa3

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_032286.1 Gene:Foxa3 / 15377 MGIID:1347477 Length:353 Species:Mus musculus


Alignment Length:466 Identity:168/466 - (36%)
Similarity:207/466 - (44%) Gaps:164/466 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 NPNPTSNGGSMSPLARSAYTMN--SMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSAS 110
            ||.||     |:|| .|..|:|  |...|.||:.      |:...:..|...|..|         
Mouse    29 NPVPT-----MAPL-NSYMTLNPLSSPYPPGGLQ------ASPLPTGPLAPPAPTA--------- 72

  Fly   111 MSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGA 175
                                       |...::.|:|:. |:.||         ||:|    |.|
Mouse    73 ---------------------------PLGPTFPSLGTG-GSTGG---------SASG----YVA 96

  Fly   176 MPPG---SREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIY 237
            ..||   .:||..|               |||...|||||||||||||||||..|.:||||||||
Mouse    97 PGPGLVHGKEMAKG---------------YRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIY 146

  Fly   238 QFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRR 302
            |:||||||:||:|||||||||||||||||||||:.|:||||||||:|.|||.|||||||||||||
Mouse   147 QWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRR 211

  Fly   303 QKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGASIAGV 367
            |||||.|:|       ....:|:..|:..|                         .||.|:.|..
Mouse   212 QKRFKLEEK-------AKKGNSATSASRNG-------------------------TAGSATSATT 244

  Fly   368 NVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDYH 432
            ...:|..|                 ..|||..|:....|    ..:::..:  :...|...|.|.
Mouse   245 TAATAVTS-----------------PAQPQPTPSEPEAQ----SGDDVGGL--DCASPPSSTPYF 286

  Fly   433 SSMH---PLKQE-PSGYTPSSHPFSINRLL----PTESKADIKMYDMSQYAGYNALSPLTNSHAA 489
            |.:.   .||.: |..:   :||||||.|:    .|.||.|:      .:.||.|.|        
Mouse   287 SGLELPGELKLDAPYNF---NHPFSINNLMSEQTSTPSKLDV------GFGGYGAES-------- 334

  Fly   490 LGQDS-YYQSL 499
             |:.. |||||
Mouse   335 -GEPGVYYQSL 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 19/91 (21%)
FH 210..298 CDD:214627 74/87 (85%)
Foxa3NP_032286.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 52..83 8/72 (11%)
FH 119..207 CDD:214627 74/87 (85%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..287 18/122 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG3563
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1181467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR11829
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
76.880

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