DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fkh and Foxd1

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_032268.2	Gene:	Foxd1 / 15229	MGIID:	1347463	Length:	456	Species:	Mus musculus

Alignment Length:	297	Identity:	103/297 - (34%)
Similarity:	127/297 - (42%)	Gaps:	94/297 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDS 96
            ||||.||||...||:......|..|.                  ..:..:..:.         |.
Mouse    38 GGGGRGGGGSRLPSSAQRRRRSYAGE------------------DDLEDLEEED---------DD 75

  Fly    97 AAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSA 161
            ...:||..|:..|                           .|........||     |||....|
Mouse    76 DLLLASRPAASPA---------------------------PPGPAPAPGTGS-----GGCSGAGA 108

  Fly   162 ASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNN 226
                ..|..|..||...|      |:.|.|                 .|||||||:||||||..:
Mouse   109 ----GGGAGGGTGAGTGG------GAKNPL-----------------VKPPYSYIALITMAILQS 146

  Fly   227 PTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSG 291
            |.:.||||||.:||...||:||:....|||||||:||.|||||||||.|..||||::|||.|:|.
Mouse   147 PKKRLTLSEICEFISSRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESA 211

  Fly   292 NMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEA 328
            :||:||.:|||:||||       ||...:| |::.||
Mouse   212 DMFDNGSFLRRRKRFK-------RQPLLAP-HAAAEA 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	15/88 (17%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	57/87 (66%)
Foxd1	NP_032268.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..104		22/124 (18%)
		Forkhead	130..216	CDD:278670	56/85 (66%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..322
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910