DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and Foxl1

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_032050.2	Gene:	Foxl1 / 14241	MGIID:	1347469	Length:	336	Species:	Mus musculus

Alignment Length:	173	Identity:	80/173 - (46%)
Similarity:	103/173 - (59%)	Gaps:	12/173 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 ASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNN 226
            |:::|:.|...|....||.......:....|..||:.|         .|||||||:||.||||:.
Mouse    10 AALAASPLLYVYSPERPGLPLAFAPAAALAGPGRVEPP---------QKPPYSYIALIAMAIQDA 65

  Fly   227 PTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSG 291
            |.:.:||:.|||||||.||||..|:|.|||||||:||.|:||||:||...:|||||:|||.|...
Mouse    66 PEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCL 130

  Fly   292 NMFENGCYLRRQKRFKDE--KKEAIRQLHKSP-SHSSLEATSP 331
            :|||||.|.||:::.|..  ..||.|...:.| |....:..||
Mouse   131 DMFENGNYRRRKRKPKPAAGSPEAKRTRVEPPESEVGCDVGSP 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	10/46 (22%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	58/87 (67%)
Foxl1	NP_032050.2	FH	49..137	CDD:214627	58/87 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..214		10/34 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..252
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910