DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and Foxi1

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_076396.3 Gene:Foxi1 / 14233 MGIID:1096329 Length:372 Species:Mus musculus


Alignment Length:482 Identity:126/482 - (26%)
Similarity:174/482 - (36%) Gaps:157/482 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 PPPSNNNPNPTSNGGSMSPLARSAYTMN---SMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASM 103
            |.||....:|........|...:.|..|   ..|:|       |||...:|..            
Mouse     7 PAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGMP-------SPQRPTSFEG------------ 52

  Fly   104 SASMSASMSASMNASMNGSMGAAAMNS---MGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMS 165
                            .|..|... |.   :.|..|||......:..||       ....|..|.
Mouse    53 ----------------GGEYGTTP-NPYLWLNGPAMTPPPYLPGTNASP-------FLPQAYGMQ 93

  Fly   166 AAGLSGTYGAMP-PGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTR 229
            ...|....|.:| |...|:                      ....:|||||.:||.|||...|.:
Mouse    94 RQLLPSDLGWLPIPSQEEL----------------------MKLVRPPYSYSALIAMAIHGAPDQ 136

  Fly   230 MLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMF 294
            .||||:|||::.|.||||.:::..|||||||:||.||||.|:||..|.||||::|||.|:...||
Mouse   137 RLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMF 201

  Fly   295 ENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEA 359
            :||.:.|::|| |.:...:...|....:.:.|.|:||...:.::                     
Mouse   202 DNGNFRRKRKR-KSDSSSSTSSLASEKTENGLLASSPKPTEPQE--------------------- 244

  Fly   360 GGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCH 424
                     ||..| |.|...     ::.|...|..|...|..::.         ||.|      
Mouse   245 ---------VLDTA-SPDTTT-----SSPEKRSSPAPSGTPCLNNF---------LSTM------ 279

  Fly   425 PSLITDYHSSMHPLKQEPSGYTP--SSHPFSINRLLPTESKADIKMYDMSQYAGYNALSPLTN-- 485
                |.|.|..:|:.:  |..||  ||.|..             ||...|  ..:|:.:||||  
Mouse   280 ----TAYVSGTNPISR--SVATPGLSSEPID-------------KMGQNS--LNFNSYTPLTNLS 323

  Fly   486 SHAALGQDSYYQSLGYHAPAGTTSLXH 512
            ||...|:        :..|..|.:|.:
Mouse   324 SHGNGGE--------WANPVATNALGY 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 16/92 (17%)
FH 210..298 CDD:214627 51/87 (59%)
Foxi1NP_076396.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23 4/15 (27%)
FH 117..205 CDD:214627 51/87 (59%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 202..271 19/105 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.910

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