DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and foxd7

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_001082957.1	Gene:	foxd7 / 100037333	ZFINID:	ZDB-GENE-070410-88	Length:	308	Species:	Danio rerio

Alignment Length:	378	Identity:	111/378 - (29%)
Similarity:	151/378 - (39%)	Gaps:	125/378 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 SREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLF 244
            :::.|...|:|:..|...|.::       .|||||||:||||||..:|.:.||||||..||...|
Zfish    41 NKDEENHVPSSICPSSSSKSSS-------VKPPYSYIALITMAILQSPKKRLTLSEICDFISHRF 98

  Fly   245 PFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDE 309
            .:||:....|||||||:||.||||||:||.|..||||::|||.|:|.:|||||.:|||:||||
Zfish    99 VYYREKFPAWQNSIRHNLSLNDCFVKMPREPGNPGKGNYWTLDPNSSDMFENGSFLRRRKRFK-- 161

  Fly   310 KKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAH 374
                                                       .||.|       .||
Zfish   162 -------------------------------------------RQHFK-------FGV------- 169

  Fly   375 SKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDYHSSMHPLK 439
            .|| :||             ||...|...:..:         .:.|:..|...:..|..|.|
Zfish   170 FKD-QAL-------------QPSGFPNLSYGAY---------GLSASCAHLPALDVYPYSFH--- 208

  Fly   440 QEPSGYTPSSHPFSINRLLP------TESKADIKMYDMSQYAGYNALSPLTNSHA-ALGQDS-YY 496
             :..|..|      :..:||      :.:....|.:..||..   |:.|:|...| |:...| |.
Zfish   209 -QHIGVPP------VGSILPALSTLFSRNSVAAKSFPQSQTV---AIEPVTPGIACAMAPTSPYA 263

  Fly   497 QSLGYHAPAGTTSLXHHQYPLAXGRAEQMLRSQQQQHLQQQHQQHQQQQQQHQ 549
            .|.....|.|...:.:.||              :.|.||..| .|.....:|:
Zfish   264 SSAALFNPVGFPRMLNFQY--------------EYQKLQNAH-SHVDLSTKHR 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	5/28 (18%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	56/87 (64%)
foxd7	NP_001082957.1	Forkhead	67..150	CDD:278670	51/82 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910