DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mIF2 and AT1G76820

DIOPT Version :9

Sequence 1:	NP_651621.2	Gene:	mIF2 / 43382	FlyBaseID:	FBgn0039588	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	NP_565140.5	Gene:	AT1G76820 / 844016	AraportID:	AT1G76820	Length:	1166	Species:	Arabidopsis thaliana

Alignment Length:	793	Identity:	180/793 - (22%)
Similarity:	298/793 - (37%)	Gaps:	233/793 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LPLAFQREFHVSAAR---LKRRKTAEEKKSPRII----EYSPKKFQTAG---------------- 66
            ||:|...:...|:.|   ..::|::.:|.:...:    |..||:....|
plant   394 LPVADDDDDATSSKRPIYANKKKSSRQKGNDTSVQVEGEVEPKENHALGEVGSADTEKVDLLESA 458

  Fly    67 ------GGASDI-----------WRHMTVAQLAKELERSLDDVQEAMLYVKGADNIEPAFK--LA 112
                  ||.:|:           |...:...:..::....||.:|...:|     ::..||  .:
plant   459 NLGEKSGGPADVAQENGVEEDDEWDAKSWDNVDLKIRGDFDDKEEEAQHV-----VKKEFKAHYS 518

  Fly   113 DLKIIQEIAKKLGAK----TRVVATPEETNADEQKERDVAPRPPAAPELLQP-----RPPVVTVM 168
            |.:..:..||..|..    ..|.|..|..:|..|.:|....:..|..|.::.     |..:..:|
plant   519 DHETEKPTAKPAGMSKLETAAVKAISEVEDAATQTKRAKKGKCLAPNEFIEEGGEKLRSIICCIM 583

  Fly   169 GHVDHGKTTLLDSLRGADVAAGEAGGITQHIGAFTVTLEN-GER--------------VTFLDTP 218
            ||||.|||.|||.:||.:|..||||||||.|||.....:| .||              :..:|||
plant   584 GHVDSGKTKLLDCIRGTNVQEGEAGGITQQIGATYFPAKNIRERTRELKADAKLKVPGLLVIDTP 648

  Fly   219 GHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALNKIDK--------- 274
            ||.:|:.:|:||:...|:.:|||....|:..||.|.:.|.:......|:||||:|:
plant   649 GHESFTNLRSRGSSLCDLAILVVDITHGLQPQTIESLNLLRMRNTEFIIALNKVDRLYGWKTCKN 713

  Fly   275 ---------------PEANIEKSK--RELAQMGLALE------EHGGDVQVIPISALKGTNL-EL 315
                           .|.|:...|  .|..:.||..|      :.|....::|.||:.|..: :|
plant   714 APIVKAMKQQNKDVINEFNLRLKKIINEFQEQGLNTELYYKNKDMGETFSIVPTSAISGEGVPDL 778

  Fly   316 LAEAVSTQATLMGLKADPTGLVEGIVVESKTDPRRGKLSTAIVSRGTLRKG-SVLLSGL------ 373
            |...|......|..|......|:..|:|.|.....|.....::..|.|.:| .:::.||
plant   779 LLWLVQWAQKTMVEKLTYVDEVQCTVLEVKVIEGHGTTIDVVLVNGELHEGDQIVVCGLQGPIVT 843

  Fly   374 -----------AHAKVRGLFDHN------------GQPLSEAPPGTPVEILGWRELPLAGDLILE 415
                       ...:|:|.:.|:            .|.|..|..||.:.::|..:         :
plant   844 TIRALLTPHPMKELRVKGTYLHHKEIKAAQGIKITAQGLEHAIAGTSLHVVGPDD---------D 899

  Fly   416 VETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEHQAKYRAEREARRLAGRFRMRGGQRVKQV 480
            :|..|           ||..|.:||....|.|..|
plant   900 IEAMK-----------ESAMEDMESVLSRIDKSGE------------------------------ 923

  Fly   481 DENEGKPRVSVIIKGDVHGSVEAILDVLETYNSNESCRLDIVHYGVGNVTEGDLELA------KA 539
                     .|.::....||:||:|:.|:|    .:..:.:...|:|.|.:.|:..|      |.
plant   924 ---------GVYVQTSTLGSLEALLEFLKT----PAVNIPVSGIGIGPVHKKDIMKAGVMLEKKK 975

  Fly   540 FHAIIYAFAVE--TPQLKAAKEVNIRSY--NIIYRL-------IDDLKEQLSSKLPPVEVEEVLG 593
            .:|.|.||.|:  |...:.|.|:.::.:  :|||:|       |:::||:        :.:|..|
plant   976 EYATILAFDVKVTTEARELADEMGVKIFCADIIYQLFNQFQVYIENIKEE--------KKKESAG 1032

  Fly   594 EA------NVLQNFLINEGRKEVPVAGCRCTKGVLKKAQKFRLLRDGEVVYD-GPLESMRHLKNE 651
            ||      .:|.|.:.|  :::..:.|.:...|:||....  :...|....| |.:.|:.:....
plant  1033 EAVFPCVLQILPNCVFN--KRDPIILGVKVHDGILKIGTP--ICVPGREFTDIGRIASIENNHKP 1093

  Fly   652 VDTIKKDVECGLR 664
            ||..:|..|..::
plant  1094 VDYAEKGDEVAIK 1106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	158..689	CDD:223606	147/614 (24%)
		IF2_eIF5B	163..327	CDD:206674	67/211 (32%)
		IF2_mtIF2_II	336..431	CDD:293903	21/124 (17%)
		IF-2	482..575	CDD:288813	27/109 (25%)
		mtIF2_IVc	593..680	CDD:293893	18/79 (23%)
AT1G76820	NP_565140.5	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1124591at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820