Protein Alignment mIF2 and eEF1alpha2

DIOPT Version :9

• Sequence 1: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_524611.1
• Gene: eEF1alpha2 / 43736
• FlyBaseID: FBgn0000557
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 115/557 - (20%)
• Similarity: 177/557 - (31%)
• Gaps: 200/557 - (35%)

  Fly   165 VTVMGHVDHGKTTLLDSLRGADVAAGEAGGI-----------TQHIG------AFTVTLENGER- 211
            :.|:||||.||:|....|      ..:.|||           .|.:|      |:.:.....||
  Fly    10 IVVIGHVDSGKSTTTGHL------IYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 68

  Fly   212 ------------------VTFLDTPGHAAFSAMRARGAVATDIIVLVVAA-----EDGVM--AQT 251
                              ||.:|.|||..|......|....|..||:|||     |.|:.  .||
  Fly    69 RGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT 133

  Fly   252 REVIQLAKEAQV-PIIVALNKIDK-----PEANIEKSKRELAQMGLALEEHGGDVQVIPISALKG 310
            ||...||....| .:||.:||:|.     .||..|:.|:|::.....:..:...|..:|||...|
  Fly   134 REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYNPASVAFVPISGWHG 198

  Fly   311 TNLELLAEAVSTQATLMGLKAD-PTGLVEGIVVESKTD----PRR----------------GKLS 354
            .|   :.|.........|...: ..|..||..:....|    |:|                |.:.
  Fly   199 DN---MLEPSEKMPWFKGWSVERKEGKAEGKCLIDALDAILPPQRPTDKPLRLPLQDVYKIGGIG 260

  Fly   355 TAIVSR---GTLRKGSVLLSGLAHAKVRGLFDHNGQPLSEAPPGTPVEILGWRELPLAGDLILEV 416
            |..|.|   |.|:.|.|:               |..|:                     :|:.||
  Fly   261 TVPVGRVETGLLKPGMVV---------------NFAPV---------------------NLVTEV 289

  Fly   417 ETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEHQAKYRAEREARR--LAGRFRMRGGQRVKQ 479
            ::.:..|               |:.::.:.........|..:.:|.||  :||
  Fly   290 KSVEMHH---------------EALTEAMPGDNVGFNVKNVSVKELRRGYVAG------------ 327

  Fly   480 VDENEGKPR------VSVIIKGDVHGSVEAILDVLETYNSNESCRLDIV----HYGVGNVTEGDL 534
             |.....||      ..||:.............||:.:.::.:|:...:    ....|..||.:.
  Fly   328 -DSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKEKCDRRTGKTTETEP 391

  Fly   535 ELAKAFHAIIYAFAVETPQLKAAKEVNIRSYNIIYRLIDDLKEQLSSKLPPVEVEEVLGEANVLQ 599
            :..|:..|.|..       |..:|.:.:.|:               .:.||            |.
  Fly   392 KAIKSGDAAIIV-------LVPSKPLCVESF---------------QEFPP------------LG 422

  Fly   600 NFLINEGRKEVPVAGCRCTKGVLKKAQKFRLLRDGEV 636
            .|.:.:.|:.|.|       ||:|.. .|:....|:|
  Fly   423 RFAVRDMRQTVAV-------GVIKSV-NFKETTSGKV 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	158..689	CDD:223606	115/557 (21%)
		IF2_eIF5B	163..327	CDD:206674	57/210 (27%)
		IF2_mtIF2_II	336..431	CDD:293903	19/117 (16%)
		IF-2	482..575	CDD:288813	16/102 (16%)
		mtIF2_IVc	593..680	CDD:293893	11/44 (25%)
eEF1alpha2	NP_524611.1	PTZ00141	1..450	CDD:185474	113/554 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840