Protein Alignment mIF2 and CG4849

DIOPT Version :10

• Sequence 1: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 817
• Identity: 152/817 - (18%)
• Similarity: 257/817 - (31%)
• Gaps: 310/817 - (37%)

  Fly    47 EEKKSPRII-----EYSPKKFQTAGGGASDIWRHMTVAQLAKELERSLDDVQEAMLYVKGADNIE 106
            |:|:...::     .|.|...:..|.....|.:......|.|.|                   ||
  Fly    52 EDKEVTAVVLHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPL-------------------IE 97

  Fly   107 PAFKLADLKIIQEIAKKLGAKTRVVATPEETNADEQKERDVAPRPPAAPELLQPRPPVVTVMGHV 171
            |..||           |...|.:.:   :||..|.:...|:...||....        |.::||:
  Fly    98 PVKKL-----------KFQIKEQDM---QETTYDMEFMADLMDTPPLIRN--------VALVGHL 140

  Fly   172 DHGKTTLLDSL---------------------------RGADVAAGEAGGITQHIGAFTVTLENG 209
            .|||||.:|.|                           ||..:.|...          |:.|::.
  Fly   141 HHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPV----------TLVLQDV 195

  Fly   210 ERVTFL----DTPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALN 270
            ::.::|    |||||..||.........:|.:||.:.|.:|||..|..:::.|.:.:..|.|.:|
  Fly   196 KQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCIN 260

  Fly   271 KIDK--------PEANIEKSKRELAQMGLALEEHGG---DVQVIPI-------SALKGTNLELLA 317
            |||:        |:....|.|..:.::...|..:|.   ::.|.||       |:|.|....|.:
  Fly   261 KIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKS 325

  Fly   318 EAVSTQATLMGL-----------------------KADPTGLVEGIVVESKTDPRRGKLSTAIVS 359
            .|.....|..|:                       |..|....:...||...:|.. ||...:|
  Fly   326 FAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMY-KLIAQVV- 388

  Fly   360 RGTLRKGSV---LLSGLAHAKVR--------------------------GLFD----HNGQPLSE 391
                  |.|   |...||...||                          |..|    |...||..
  Fly   389 ------GDVDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLEN 447

  Fly   392 APPGTPVEILGWRELPLAGDLI-------LEVETEKK-----------AHAVLKYREHESQQEKI 438
            |.........|.:|..:..|:|       |.|.:.|.           ...::....|..|:.::
  Fly   448 AKRKVDHIYTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRV 512

  Fly   439 ESSSDEIRKKEEEH----------QAKYRAEREARRLAGRFRMRGGQRVKQVDENEGKPRVSVII 493
            ...:..::.:|:..          :::|:.|.. |..||.:.:     ::.:|:        .|:
  Fly   513 LGENYTLQDEEDSRILQVGRLWVFESRYKVELN-RVPAGNWVL-----IEGIDQ--------CIV 563

  Fly   494 KGDVHGSVEAILDVLETYNSNESCRLDIVHYGVGNVTEGDLELAKAFH---AIIYAFAVE----- 550
            |      ...|:|:                    ||.| ||.:.:...   ..|...|||
  Fly   564 K------TSTIVDI--------------------NVPE-DLYIFRPLKFNTQSIIKIAVEPVNPS 601

  Fly   551 --TPQLKAAKEVNIRSYNIIYRLIDDLKEQLSSKLPPVEVEEVLGEANVLQNFLINEGRK----- 608
              ...|...::|| :||.::...:::..|.:           :||...:..:.::::.||
  Fly   602 ELPKMLDGLRKVN-KSYPLLSTRVEESGEHV-----------ILGTGELYLDCVMHDLRKMYSEI 654

  Fly   609 -----EVPVAGC---------RCTKGVLKKAQKFRLLRDGEVVYDGPLESMRHLKNEVDTIKKDV 659
                 :..||.|         :|......|..|..::.:       |||.         .:.:|:
  Fly   655 DIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISE-------PLEK---------GLAEDI 703

  Fly   660 ECG---LRFRDTKVLPQAGDILQCYTTKMEAQQTDWD 693
            |.|   :.:...::    |:..|.        ..|||
  Fly   704 ENGTVCINWNKKRI----GEFFQV--------NYDWD 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	159..688	CDD:440298	127/693 (18%)
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968	16/88 (18%)
		PRK13351	115..957	CDD:481252	134/721 (19%)