Protein Alignment mIF2 and eEFSec

DIOPT Version :9

• Sequence 1: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_611584.1
• Gene: eEFSec / 37444
• FlyBaseID: FBgn0034627
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 132/565 - (23%)
• Similarity: 229/565 - (40%)
• Gaps: 141/565 - (24%)

  Fly   165 VTVMGHVDHGKTTLLDSLRG-ADVAAGEAG------GITQHIGAFT-------VTLENGERV--T 213
            :.::||||.|||||..:|.. :..||.:..      |||..:| |:       ..|..||::  |
  Fly     7 IGLLGHVDSGKTTLAKALSSISSTAAFDKNPQSVERGITLDLG-FSGLLVDAPAHLPQGEQLQFT 70

  Fly   214 FLDTPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALNKIDKPEAN 278
            |:|.||||:.......||...|:::|||.|:.|...||.|.:.:.:..|..:||.:||||....|
  Fly    71 FVDCPGHASLIRTIIGGAQIIDLMLLVVDAQKGKQTQTAECLIIGELLQKKLIVVINKIDVYPEN 135

  Fly   279 IEKSKRELAQMGLA--LE--EHGGDVQVIPISALKGTNL----ELLAEA-VSTQATLMGLKADPT 334
            ...||.|..::.||  ||  ..||.|.:..:|||:||::    |:|.|| ...|..|    |||.
  Fly   136 QRASKLEKLRLRLAKTLEATTFGGQVPICAVSALQGTHIAELREVLREAYFQPQRNL----ADPL 196

  Fly   335 GLVEGIVVESKTDPRRGKLSTAIVSRGTLRKGSVLLSGLAHAKVRGLFDHNGQPLSEAPPGTPVE 399
            .:.        .|...|......|..|||.:|.|.::.:.
  Fly   197 FMY--------VDHCFGIKGQGTVCTGTLLQGKVQVNNVI------------------------- 228

  Fly   400 ILGWRELPLAGDLILEVETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEHQAKYRAEREARR 464
                 |||..|:       ::|..::..:|::.:.    .|..|.|.....:..||. .||....
  Fly   229 -----ELPALGE-------QRKVKSIQMFRKNVTS----ASMGDRIGLCVTQFNAKL-LERGIIT 276

  Fly   465 LAGRFR--------MRGGQRVKQVDENEGKPRVSVIIKGDVHGSVEAILDVL-ETYNSNESCRLD 520
            ..|..:        .:..:..|:|.::..|..:||     .|.:|.|.:.:. :|..:..:.:||
  Fly   277 QPGYLKPIYAVCLQFKPIRYYKEVIKSMRKMHISV-----GHNTVMANVTLFRDTDGTTSTFQLD 336

  Fly   521 IVHYGVGNVTEGDLELAKAFHAIIYA-FAVETPQLK------AAKEVNIRSYNIIYRLI------ 572
            ..:..:.:|...:::    .:.:||| ...|:|.|.      .|.::::..::...||.
  Fly   337 KEYEYMEDVQPAEVQ----HNDVIYALLQFESPVLSPPHSTLIASKLDMDVHSTSCRLAFWGRIA 397

  Fly   573 --DDLKEQLSSKLPPV----------EVEEVLGEANVLQNFLINEGRKEVPVAGCRCTKGV-LKK 624
              ....:....:||.:          .::.|:..:.|:...|..:.::::.|.     |.| |..
  Fly   398 WQTHSSKYFQEELPKLRIFKRKQKVGSIQRVVNSSEVIVQNLFKDAKRDLYVG-----KNVELST 457

  Fly   625 AQKFRLLRD-GE-----VVYDGPL--ESMRHLKNEVDTIKKDVEC 661
            .:|.|:.|. |:     :.:...|  |::.::||    :|..:.|
  Fly   458 GEKGRIERTFGQTSKVAITFQDALSPETISNVKN----VKVLLNC 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	158..689	CDD:223606	132/565 (23%)
		IF2_eIF5B	163..327	CDD:206674	66/186 (35%)
		IF2_mtIF2_II	336..431	CDD:293903	14/94 (15%)
		IF-2	482..575	CDD:288813	19/108 (18%)
		mtIF2_IVc	593..680	CDD:293893	16/78 (21%)
eEFSec	NP_611584.1	SelB_euk	5..192	CDD:206676	66/185 (36%)
		SelB	6..467	CDD:225815	125/528 (24%)
		SelB_II	196..278	CDD:293897	21/131 (16%)
		eSelB_III	283..396	CDD:294009	21/121 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840