Protein Alignment mIF2 and mti2

DIOPT Version :10

• Sequence 1: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_595135.1
• Gene: mti2 / 2540181
• PomBaseID: SPBC1271.15C
• Length: 686
• Species: Schizosaccharomyces pombe
• Alignment Length: 620
• Identity: 226/620 - (36%)
• Similarity: 349/620 - (56%)
• Gaps: 52/620 - (8%)

  Fly    76 MTVAQLAKELE----RSLDDVQEAMLYVKGADNIEPAFKLADLKIIQEIAKKLGAKTRVVA---- 132
            ::||..|..|:    |.|.|:...     |..::.|.: |...:....:|::.|...:..|
pombe    96 LSVASFANLLQIPTRRILRDLNRL-----GIKDVFPEY-LITYEYSSLLAEEYGFDVQEAAAYSA 154

  Fly   133 -TPEETNADEQKERDVAPRPPAAPELLQPRPPVVTVMGHVDHGKTTLLDSLRGADVAAGEAGGIT 196
             :|:..|:    ::|..|.          ||||||:|||||||||||||:.|.:.:|:.|.||||
pombe   155 PSPKSLNS----KKDSGPL----------RPPVVTLMGHVDHGKTTLLDAFRKSTIASTEHGGIT 205

  Fly   197 QHIGAFTVTLENGER-VTFLDTPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKE 260
            |.||||||..:.|.: :||||||||.||.|||.|||...||:|||||.:|||..||.|.|:..:.
pombe   206 QKIGAFTVPFDKGSKFITFLDTPGHMAFEAMRKRGANIADIVVLVVAGDDGVKPQTVEAIKHIQS 270

  Fly   261 AQVPIIVALNKIDKPEANIEKSKRELAQMGLALEEHGGDVQVIPISALKGTNLELLAEAVSTQAT 325
            |.||::|||.|.|:|...|.|...:|...|:.:|..||:.|:|||||..|..:..|..|:.|.|.
pombe   271 ADVPVVVALTKSDRPGTPIHKIYEQLLNNGIQVEALGGETQIIPISAKTGKGIPELEAAILTLAE 335

  Fly   326 LMGLKADPTGLVEGIVVESKTDPRRGKLSTAIVSRGTLRKGSVLLSGLAHAKVRGLFDHNGQPLS 390
            :|.::|.|....:|.:|||......|..:|.:|.|||::||..|::|.:..|||.|.|.|.:.:.
pombe   336 IMEIRASPRDPFQGWIVESSVTKGVGSSATVVVKRGTVKKGMYLVAGKSWCKVRSLVDVNKKSIK 400

  Fly   391 EAPPGTPVEILGWRELPLAGDLILEVETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEHQAK 455
            :..||...::.||::||:||||..||::|.:|..:|               ||..|:..|::..:
pombe   401 QVLPGQAAQVYGWKDLPIAGDLAYEVKSESEAKRIL---------------SDIYRQSNEQNFYE 450

  Fly   456 YRAEREARRLAGRFRMRGGQRVKQVDENEGKPRVSVIIKGDVHGSVEAILDVLETYNSNESCRLD 520
            ....:..:|::.....:.|....| :|.......::|.|.:..||:||:.|.|:.....: .:..
pombe   451 LAESQNEQRVSALAAKKSGPAAIQ-EETSVSKSFNIIAKCEDTGSMEALSDYLKPLQFGK-VKSR 513

  Fly   521 IVHYGVGNVTEGDLELAKAFHAIIYAFAVETPQ--LKAAKEVNIR--SYNIIYRLIDDLKEQLSS 581
            :::.|||.|||.|:|.|:...|||.:|.|..|:  .:.|::.|::  .:|:||.|:||:::..:.
pombe   514 VLYTGVGPVTETDIERAETSDAIIISFGVSVPKATFRLAEKHNVKLLFHNVIYHLMDDVRKLFAL 578

  Fly   582 KLPPVEVEEVLGEANVLQNFLINEGRKEVPVAGCRCTKGVLKKAQKFRLLRDGEVVYDGPLESMR 646
            :|||:.|:.|.|||.:...|.|...|..|.|||||.|.|.::|:.|.||:|:.::::.|.::|::
pombe   579 RLPPILVQRVTGEAIISAIFDIKAKRAVVHVAGCRVTNGTIEKSHKIRLVRNDKIIWSGEIDSLK 643

  Fly   647 HLKNEVDTIKKDVECGLRFRDTKVLPQAGDILQCY 681
            |||.||.:|||..|||:..::...: ..||.||.:
pombe   644 HLKEEVTSIKKGRECGILLKNFDEI-VTGDKLQTF 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	159..688	CDD:440298	209/528 (40%)
mti2	NP_595135.1	IF2_N	93..145	CDD:428110	12/54 (22%)
		InfB	170..683	CDD:440298	209/526 (40%)