Protein Alignment mIF2 and LOC1278404

DIOPT Version :10

• Sequence 1: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_061498204.1
• Gene: LOC1278404 / 1278404
• VectorBaseID: AGAMI1_008565
• Length: 1210
• Species: Anopheles gambiae
• Alignment Length: 787
• Identity: 187/787 - (23%)
• Similarity: 300/787 - (38%)
• Gaps: 220/787 - (27%)

  Fly    45 TAEEKKSP--RIIEYSPKKFQTAGGGASDIWRHMTVAQ--LAKELERSLDDVQEAMLYVKGADNI 105
            |.|.:..|  ||   .|||.|.|...|||.......|:  .|||.|::.:            ..:
Mosquito   461 TGERRPKPGSRI---RPKKNQDANKEASDSKETTPTAEELKAKEEEKAKE------------KEV 510

  Fly   106 EPAFKLADLKIIQEIAKKLGAKTRV---------VATPEETNADEQKERD--------------- 146
            :.::.:.|.:..:|..||...|.:.         |.:.|...:|::::.|
Mosquito   511 KESWDVTDSEGEEEEVKKPAGKQKTGVELSQQQSVESKESRGSDDEEDDDEDEEGEDGSDEDDDD 575

  Fly   147 ---------------------------VAPRPPAAPE---LLQPRPPVVTVMGHVDHGKTTLLDS 181
                                       :|.|...|.:   |...|..||.|:||||.|||.:||.
Mosquito   576 SSDDDDDSEGGDQHREVENIRQRALDRIASRTQDAEKKKTLDNLRAAVVCVLGHVDTGKTKILDK 640

  Fly   182 LRGADVAAGEAGGITQHIGAFTVTLENGERVT-----------------FLDTPGHAAFSAMRAR 229
            ||..:|..||||||||.|||..|..||.:..|                 .:|||||.:||.:|:|
Mosquito   641 LRRTNVQDGEAGGITQQIGATNVPSENIKEQTRFVKGFQELEFKLPGLLIIDTPGHESFSNLRSR 705

  Fly   230 GAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALNKIDK-------PEANI-------- 279
            |:...||.:|||....|:..||.|.|.|.|..:.|.:|||||||:       |..::
Mosquito   706 GSSLCDIAILVVDIMHGLEPQTIESINLLKSKRTPFVVALNKIDRLYDWNTMPRKDVRDILKAQA 770

  Fly   280 --------EKSKR---ELAQMGL--ALEEHGGD----VQVIPISALKGTN----LELLAEAVSTQ 323
                    :::|.   :.|:.||  ||.....|    |.::|.||:.|..    |.|:.:....|
Mosquito   771 SNTQLEFNQRTKEIIVQFAEQGLNAALFYENPDPKTYVSLVPTSAITGEGMGNMLFLIVQFCQKQ 835

  Fly   324 ATLMGLKADPTGLVEGIVVESKTDPRRGKLSTAIVSRGTLRKG-SVLLSGLAHAKVRGLFDHNGQ 387
            .....:.::.   ::..|:|.|..|..|....||:..|.||:| :::|:|
Mosquito   836 LAKRLMYSED---LQATVLEVKAIPGLGTTIDAILINGKLREGDTMILAG--------------- 882

  Fly   388 PLSEAPPGTPVEILGWRELPLAGDLILEVETEKKAHAVLKYREHESQQEKIESSSDEIRKKEEEH 452
              :|.|..|.::.|            |..:..|:......|.||   :|.:.:...:|..||.|.
Mosquito   883 --TEGPIVTQIKAL------------LMPQPMKELRVKNAYVEH---KEIMAAQGVKIAAKELEK 930

  Fly   453 -------QAKYRAEREA--RRLAGRFRMRGGQRVKQVDENEGKPRVSVIIKGDVHGSVEAILDVL 508
                   |..::.:...  |.:..|........:|..|.       .|.::....||:||:|:.|
Mosquito   931 AIAGLNLQIAHKPDEVEIFREIVARDLKSALNSIKLSDR-------GVYVQASTLGSLEALLEFL 988

  Fly   509 ETYNSNESCRLDIVHYG--VGNVTEGDLELAKAF------HAIIYAF--AVETPQLKAAKEVNIR 563
            .|..        |.:.|  :|.|.:.|:..|...      :|.|.||  .||......|..:.::
Mosquito   989 RTSK--------IPYSGIRIGPVVKRDVMKASTMLEHENQYATILAFDVKVERDAQDLADNLGVK 1045

  Fly   564 SY--NIIYRLID-------DLKEQLSSKLPPVEVEEVLGEANVLQNFLINEGRKEVPVAGCRCTK 619
            .:  :|||.|.|       ::|::...:...:.|...  :..:|...:.|.  ::..|.|.....
Mosquito  1046 IFQADIIYHLFDKFMAYREEIKQRKRDEFKTIAVFPC--KLKILPQCVFNS--RDPIVMGVMVEA 1106

  Fly   620 GVLKKAQKFRLLRDGEVVYDGPLESMRHLKNEVDTIKKDVECGLRFRDTKVLPQAGDILQCYTTK 684
            |::|:.... .:...|....|.:.|:.....::::.:|..|..|     |:.|..|:     |.|
Mosquito  1107 GIVKEGTPI-TVPSKEFTDIGVVTSIEANHKQLESARKGQEVCL-----KIEPIPGE-----TPK 1160

  Fly   685 MEAQQTD 691
            |..:..|
Mosquito  1161 MYGRHFD 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mIF2	NP_651621.2	InfB	159..688	CDD:440298	155/610 (25%)
LOC1278404	XP_061498204.1	None