DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc98D and CG3339

DIOPT Version :9

Sequence 1:	NP_524541.3	Gene:	Dhc98D / 43379	FlyBaseID:	FBgn0013813	Length:	5080	Species:	Drosophila melanogaster
Sequence 2:	NP_001036762.2	Gene:	CG3339 / 43295	FlyBaseID:	FBgn0039510	Length:	4842	Species:	Drosophila melanogaster

Alignment Length:	5404	Identity:	1482/5404 - (27%)
Similarity:	2415/5404 - (44%)	Gaps:	1038/5404 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 DAAAPAGGDQEAVEEVNTGG------ETTDAEVEGELEGEEEATVAGSGKSSARSRPSSDTENGS 203
            ||||.|..|:|.:...:|.|      :.:||.:|         .||....::.|.:|       .
  Fly     3 DAAAMASSDEEGLPAGSTSGRQRVQRDYSDARLE---------RVAAYTTTTMRLKP-------D 51

  Fly   204 KFRKKKA-------------------------------------TYVPVYVEVKK------LVPA 225
            |:.|..|                                     .|:|..|:..:      ::||
  Fly    52 KWTKMMACDDLRRIVVEWQHGHRRVLVMTLSPGGDLVPRSCLSDLYLPYSVQSARGSIPSAMLPA 116

  Fly   226 -----------------------YVKTPQVHCHFGRMESCDLDPKIKYIYIVRKNRREIP----N 263
                                   .:..|.....|..::..   |:.|..|.||:|..:.|    |
  Fly   117 EDEAMATVTAAVSAVVSATPGALLIPLPPASSSFTTLDGV---PRGKCAYFVRRNTSDGPLTASN 178

  Fly   264 FSDVSACFAQMPLYFLLGTVRGSLINSLRDDLNLVYKSAIQFQFREPATADSQQMDSYEGQAGGS 328
            |:: |..:...|            ::|..:.::|::...:|
  Fly   179 FAE-SVLYGDFP------------VHSKIETMSLLFDDVLQ------------------------ 206

  Fly   329 GGGGAGGPAGETGEDISSEAKESGPGLLELSKPSEFRLRALKQQKKMKEKEAAAKKAKAKKTD-- 391
                          .:..:|:...|.::...           .|.::||......:.|.|..:
  Fly   207 --------------PLLEQAQSQWPAIVRKD-----------LQARIKEVRNTLTEIKGKTNNRT 246

  Fly   392 -----AEPTEEEEEADAHKVEAHLSSSEEEVEIKVEKLTIGQRWEKMLNETKAKVEAEHAAEEAT 451
                 ..|| ..||..||..:.||.
  Fly   247 ILSLLVSPT-IVEEVFAHVSQGHLR---------------------------------------- 270

  Fly   452 PPRITPIQRRLLKEIEEFQSEITWTINHIVWAFSLPSSYILPGQEATEFEDAII-RVPVDPKRLD 515
             |.:.|..|.||:|:     .|.||                     |:..|.:: |....|
  Fly   271 -PALDPKFRNLLEEM-----FINWT---------------------TQMHDIVLERSECQP---- 304

  Fly   516 LVITYTQQQLEEVVDGWIKYLKKTMKTLTDAKLDDFTPMAEHRYWHKMEVELYGTLEQLKTEFVV 580
             :.:.||....:.     ||:  |:.:|         |..|..:|...::.|....|||:.....
  Fly   305 -LGSTTQSAGHQP-----KYI--TLVSL---------PAQEIGFWTNRKLNLQNIYEQLRESTHK 352

  Fly   581 AVLQRLTDDKSPVLDEWQAVVEKTEARFKLAKENSDYLGTIIDYLEKVRSYESFKMVVLQIPN-- 643
            .:.|.|...:|...:.:.....|..|.:..|::.|.:|..::      |...:|..|  |..|
  Fly   353 TLAQILERIESVYYEPYATAFRKLVAAWLEAQDVSLWLQPLL------RQTAAFNSV--QFSNGH 409

  Fly   644 -IMVGLRHI----WTMSSHYCRDPEMQVLLCQISNVFVQKVKSIINFENIFKYSATYTYETATNC 703
             ::..|.||    |:.:.:|.....|.|||..|.|:.|.:....:..:.:|:..|..........
  Fly   410 DLVAPLVHIVHLVWSNARYYRSTQRMSVLLRCICNMLVHRAAEDLELQLLFQGDADEGLLKINRT 474

  Fly   704 ANLLRCWKQA---YKLSRQHIEDSGAGSR-------------------------WEFDRVALFNE 740
            ..:|..:||.   ||       :..|||:                         |.|....:|.:
  Fly   475 IAVLELFKQRMLDYK-------ERYAGSQVLLPALSEGAAAVASSPSPDDQQQLWRFCHEDVFGQ 532

  Fly   741 VNHIHRVAVDIAYVGRVF---VQYENLFGHRLKACIADPSIVDNLMRKV---YRMLDDLIKSVDY 799
            .  :...::.:..:.:||   ||::.|  .:|:.......|:...:|::   :::|.:...:||.
  Fly   533 T--LDGFSLQLLELRQVFEAAVQFQQL--EKLEVGGLRGKILTERVREIFGEFKVLFEQWSNVDI 593

  Fly   800 DMFR--PGNWENWEYSLELFNKRLDNVENEAKNVIDQSINSLLSSEKGLDLVVNAMNIDTRATLQ 862
            |:..  ...|:.:.....||..|:..:|.:...|:.|:.....|....|.|.:...::..|..::
  Fly   594 DLTATVASKWKCFRREQTLFFSRMQLLEQKLATVLLQAFEQCHSWMHLLRLTLMFGSLLQREAVR 658

  Fly   863 EFVATKHENLLRFFVTEINAVE------------RVFTKLKKSPPMAKHQPAKISAIFWARLLGK 915
            ..:|....::|..:.||:..:|            |....|    |:|.:.|...:|:.|
  Fly   659 PELARVLPHILFIYDTEMEQLEDSVGEVLLGYEIRGLAAL----PLANNFPPIANAMMW------ 713

  Fly   916 KLKTSVLAFKRVEDEPAIKNSFLKRSSFKQYFELMTVMFQFEKVLFENFIQNATYLVNTTNRSNV 980
             |:..:   .|.::..|.:.|.|.....|:..||.|:..|:..:|               :|.|:
  Fly   714 -LEQHI---SRCDEFGAKELSQLVEQLLKEKSELQTLPIQWNSLL---------------SRRNI 759

  Fly   981 LRIRICKESTMSYIS--EAVQTLKAKPRPELQMTSDRRVTPVK---SSNLMPVQSEAFSAYSVAD 1040
            |..::.......:||  |.|..|..:...|..::..:.::.:.   |..|..:..|  :.|.:|.
  Fly   760 LTTKLSNLQMKIWISWHECVDKLIIQGLDESVLSRSQDLSQLHLNFSQVLFTLLKE--TKYLLAL 822

  Fly  1041 SAGTEISSESENEGLLVGDTSQ--KKLMCRINRLTVLVAMIMWMVSNTRKAN-IQLQECTAF-IK 1101
            .|          .|.|.||..|  :.|:.............:.::......| |:..||.|. ::
  Fly   823 QA----------TGSLSGDLFQLPEPLLTLYGHRDAYWERRIRLIKIGEFYNGIRSGECAAAELQ 877

  Fly  1102 MVKDKKPKDVTAMDRHCVRTCELLQRAESQYLLPIWRELVGEKTLIEYDMDFVVNL---KRDVFD 1163
            ::::    |:.::|.|....|:.|          .||         .|:.:.|..:   .||:|.
  Fly   878 LIRN----DLASIDEHVEVACQQL----------TWR---------NYNDELVAGIFEQSRDLFA 919

  Fly  1164 VLFEAQQFEHLGFTLPAVL-------RTAIMKKDLLFKDYERMTEVVDRYR----------SIIN 1211
            .|.::..      .|.|:|       |..:.::.|..::...:....||.|          .::|
  Fly   920 RLQQSHG------NLDAILASMRRWSREPLHQRSLYGRNLLDLRHQQDRVRLRLLQCDETKMLLN 978

  Fly  1212 NLSMSEVIFLRGH------IYDTELFIQMGVGRYTWTSFNIGKFCDQINSQLRKLTSIVSQINFI 1270
            .|.::.......:      :|..:|.:|         .| |.:|.::...|..|..:.|
  Fly   979 RLLIANFCLFFNYESQEFQLYSRDLSVQ---------EF-IREFPEEQRRQYNKYLASV------ 1027

  Fly  1271 RLDLRSRIDMIKSFNLFNLDDEL---KVEDTSRSSGESYLQDRKNPSQRFKSVTGETITMFSVEK 1332
                                |||   :|.:..|.|.| ||         :|.:|. |.|..:...
  Fly  1028 --------------------DELICREVREAMRISLE-YL---------YKEMTA-TATATTTPT 1061

  Fly  1333 DVPAD-----------------EKAEQACGSGIYPCQGYFELLEASRNRKAAQMKKLYDSLGPVL 1380
            ..|.|                 .:|....|:|            ||.....|....|::
  Fly  1062 APPVDPGCSAGMARLVLQQITTPQATSTAGAG------------ASGAPPTANDAPLFE------ 1108

  Fly  1381 VKLESLVLGTFSGRSDRMKTYYEYWEGETFKCIVDMTYQNLKCYINRLLSNKPMFEVNAVLL--- 1442
            ||||              .|..|......|...|:..:|.:               |..:||
  Fly  1109 VKLE--------------LTETEIRFSPAFDASVENNFQQI---------------VEQLLLDIK 1144

  Fly  1443 -----MSEIVLEPSVQELQNTIVTATKDYISRLRIFTRW-------------------------- 1476
                 |..||.:.:..|......|||.||...|    ||
  Fly  1145 QTCDCMPRIVADNAPSEDDEDDDTATVDYEQEL----RWEPREDRAQELQERKKKDLELEQEQGD 1205

  Fly  1477 MTGTCIACPLVEMGKQFKYNYTYYEDVIQI--RSIVDLVINIHDLASRVANEARGFVSQFRKYFN 1539
            .....:...|:...|.:........|.:::  |:|.|.      ||..|| .|..:.::|:.|..
  Fly  1206 PKPQAVQFNLLAAAKAYSQKMECTADGLEMLERAIRDA------LADTVA-AASAYAAKFQAYAF 1263

  Fly  1540 LWAFEKSFI---CQKFLEKQVTLIEIDEKFTFYSSIVETLANTRKFQDI-------KCVR----I 1590
            ||..:.|.:   |.:...:|...:... .:....:..:.:.|..:..|.       :|:.    :
  Fly  1264 LWTQQSSEVLAACMQTAREQTHHVSAG-GYAIMETFKKEIENYNEVHDAIDQCENRECINGWLAL 1327

  Fly  1591 NLEPLLASITQHAQDWCTTLGEELLRHVNDNMRAMRNEV----KTLSLNLNKTTRELEDFKL--- 1648
            :::||...:...|..|.....:.|||:|...::.:...:    :||.|::.:     :||..
  Fly  1328 DIKPLKYGLLNLACKWSHMCKKWLLRYVQGTLKELNAFIARGFETLQLHIAR-----QDFATLLR 1387

  Fly  1649 VMTTIGTVQSSTLTNEQKIHEMQETFTILSEHKIMFPYEDMLMAHHLEKRWKRLFLSALYRYEKL 1713
            |:..:..::......:.....::|...:|..:.:.|..:.:.....|.::|::|..|:..:.|.|
  Fly  1388 VLAIMSEIREREPYADNVFKPLKEIMGLLKTYNVEFEPQLLRGIEQLPQQWQQLKHSSTVKQEAL 1452

  Fly  1714 QPI---------------------------KQKFADMTSVEIDEFCDDLAEFIKDYDENGPGSVG 1751
            |..                           |..|..:...::.:.||::.
  Fly  1453 QDTRFHQQQRVTALIGLHTCHLQHYARQFQKMPFFRVPCPQVYDVCDEVY--------------- 1502

  Fly  1752 AELERGVRLMDPYGQKIAERESRREEL-ANAERLFDMAMVDYHEFARVQTEFEGLQQLYKLYKAQ 1815
                  :||         .|..|::.| ....||.|:...|.......:.|...::||:...:..
  Fly  1503 ------LRL---------HRFRRQQRLYTRWARLLDIQPPDPATLQFCEVELRRVKQLWDFVRVI 1552

  Fly  1816 KYAREGWGKTLWADLDPNVLTEGVESYLKEFRKFTKAVRTLP------------VGVQLEIHMKQ 1868
            :.....|..|.|..:|    |:.:|   .|.:|||:.:|||.            |||     :::
  Fly  1553 ESCIVAWHATPWLLID----TDDME---HECKKFTRDLRTLDKCIREWAPYVHIVGV-----LRE 1605

  Fly  1869 FKGTVPLMVSLKHEALRERHWLQLMEKTGQYFDMSPARFTLENMFAMQLHKYQEIAEQILTNAIK 1933
            ...::..:..|::.|:.||||::||:.|...:..:.:. .|..:..:||..::|..:..:..|||
  Fly  1606 LVASLRAITELQNPAITERHWMELMQLTKLSYKCNKST-RLAQLLTLQLQHHEEDIKNTVDRAIK 1669

  Fly  1934 ELQIERGVQAVIETWASMAFKTFKHFKGSDDRGWVLGPVDEIMQILEDNAMNLQSMGASQFIGPF 1998
            |:.:.:.:..:..|||.:.|:..:|......:  :|...:|:::.|:||.|.||::..|:.|...
  Fly  1670 EMTVTKVLDEIKATWAHLEFELEQHHTRPHIQ--LLKVSEELIETLDDNQMQLQNISTSKHIEYL 1732

  Fly  1999 LETVNKWERTLALISEIIDEWLVVQRKWLYLEGIFIG-GDIRTQLPEEARKFDDIDKSYRRIMVD 2062
            |:.:..|::.|..|..:|..|..|||||:|||.|||| .|||.|||.:|..|:.||:.:..::..
  Fly  1733 LDKLTHWQKVLGGIDTLIVNWFEVQRKWIYLECIFIGSADIRAQLPADAANFERIDEDFTALLAK 1797

  Fly  2063 CAKNPLVVPFC----TVPGRLVEIQGLGIGLENCQKSLNEYLDSKRRIFPRFYFISTDELLSILG 2123
            ..:..:|:...    .|..:|:::|.   .|..|:|:||:||::||..||||||||..:||.||.
  Fly  1798 VQEVRVVMQVVLRHDDVLAQLLQLQH---RLAVCEKALNDYLETKRLAFPRFYFISAADLLDILS 1859

  Fly  2124 S-SEPSAVQNHIIKMYDNIKSLRLVKEGSQTIVTGMISSEGE----VMEFRHSARA----AGRVE 2179
            : :.|..:..|:||::|:|  |||..|.:.....||.|.|.:    .:.|.....|    .||||
  Fly  1860 NGNNPQVIDRHLIKLFDSI--LRLQYETNTPNALGMHSKENDEYVPFVSFDPDQPAFIVCGGRVE 1922

  Fly  2180 YWMNDVLDEMRRSNRFINKTAIYDFGTDLQISRPDWLMNYQGMVGLAASQVWWTAEVEEAFDQAQ 2244
            .|:..::.:||.:...:.:.|:..||   :..|..||.::...|.|..||:.|||:|..:|. ..
  Fly  1923 LWLRAIIQQMRSTLHELFRRALRVFG---EKPRELWLYDWPAQVALCCSQISWTADVNRSFG-CM 1983

  Fly  2245 NHGNMRAMKDFLGKNNYQIEELVLKVRSNLSRNDRLKFKAQCTVDVHARDIIDNFVRDNVLDASE 2309
            ..|....||:...:...|:..|:..:...||..||.|....||:|||:||::...:...|.::..
  Fly  1984 EEGYEGVMKELHKRQIAQLNALINLLLGELSPGDRQKIMTICTIDVHSRDVVGKIIASKVDNSLA 2048

  Fly  2310 FSWESQLRFYW----------------------IKFYDNLHVLQCSGSFDFGYEYMGLNGRLVIT 2352
            |.|:||||..|                      ...:.|:    |...|.:.|||:|...|||||
  Fly  2049 FQWQSQLRHRWDDDQAGSSSGRASTAISCGGGDEDCFANI----CDAEFRYAYEYLGNTSRLVIT 2109

  Fly  2353 PLTDRIYLTITQALLMNLGGAPAGPAGTGKTETVKDLAKAMGLLCVVTNCGEGMDYRAVGTILSG 2417
            |||||.|:|:||:|.:.|.||.|||||||||||.|||.:|:|::..|.||.|.|||::.|.|..|
  Fly  2110 PLTDRCYITLTQSLRLRLAGATAGPAGTGKTETTKDLGRALGVMVYVFNCSEQMDYKSCGNIYKG 2174

  Fly  2418 LVQCGAWGCFDEFNRIDISVLSVISTQLQTIRNGLIRKLDRFVFEGVEIHLDPKCGVFVTMNPGY 2482
            |.|.||||||||||||.:.||||::.|::||:..:.....:|:|.|..|.|:|..|:|:||||||
  Fly  2175 LAQTGAWGCFDEFNRICVEVLSVVAVQVKTIQEAIKMHKTQFIFMGERISLEPSVGIFITMNPGY 2239

  Fly  2483 AGRTELPESVKALFRPVTCIKPDLELICLISLFSDGFLTAKVLAKKMTVLYSLAQAQLSKQCHYD 2547
            ||||||||::|.||||...|.||..|||.|.|.::||..|::||:|...||:|.:..||||.|||
  Fly  2240 AGRTELPENLKTLFRPCAMIVPDFALICEIMLMAEGFQDARLLARKFITLYTLCKELLSKQDHYD 2304

  Fly  2548 WGLRSLNSVLRMAGVMKRQSEDLPEAVVLMRVLRDMNFPKFVFEDVPLFLGLIKDLFPGIDCPRI 2612
            ||||::.|||.:||.:||.....||..||||.|||.|.||.|.||||:|:|||.||||.:|.||.
  Fly  2305 WGLRAIKSVLVVAGTLKRDDHSRPEDQVLMRALRDFNIPKIVTEDVPIFMGLIGDLFPALDVPRK 2369

  Fly  2613 GYPDFNAAVRHVLVNDGYILLPDQED---KVVQMYETMMTRHSTMLVGPTGGGKTVVINALVKAQ 2674
            ...:|...:|.. ||:  |.|..:|.   ||||:.|.:..|||..:||..|.|||.:...|.:..
  Fly  2370 RVFEFEKTIRRA-VNE--IKLQPEEGFLMKVVQLQELLDVRHSVFIVGNAGTGKTKIWQTLRETY 2431

  Fly  2675 THMGLPTKCLVLNPKACSVIELYGFLDMETRDWIDGLFSNIFREM-NKPIEREERRYACFDGDVD 2738
            ....|...|.||||||.|..||:|.::..||:|.|||||:|.||. |.|  ....::...|||:|
  Fly  2432 RIQKLKPVCHVLNPKALSNDELFGIVNPTTREWKDGLFSSIMREQANMP--PGNPKWIVLDGDID 2494

  Fly  2739 ALWIENMNSVMDDNKLLTLANGERIRLENYCALLFEVGNLNYASPATVSRAGMVYVDPKNLRYSP 2803
            .:|||::|::|||||:||||:.|||.|:....||||||:|..|:||||||||::|::|::|.:||
  Fly  2495 PMWIESLNTLMDDNKILTLASNERISLKREMRLLFEVGHLKAATPATVSRAGILYINPQDLGWSP 2559

  Fly  2804 FWQRWVLTRPEP-QRELLNDFFEKIITQSIAFILEGLDGTTQGNPLKLVIMQTDLNMVTQFCNLY 2867
            :...|:.||.:. :|.:||..|||.    ...:::......:..|:      ||:.|:...|:|.
  Fly  2560 YVSSWLETRVDMIERGILNALFEKY----FPCLMQRQRDFRRITPI------TDMAMIQMTCHLL 2614

  Fly  2868 DALLPNYVMDSKNYD------------EPVQQNYNTDS-------LECCFLQAVYGSMGACLVEK 2913
            :.||.:   |..|.|            .|...::...|       ||..|:.|...|.|:.|
  Fly  2615 ECLLDS---DEGNADGRGRGSATGGAANPHSLHHGELSHEAMVMALETIFVYATVWSFGSAL--- 2673

  Fly  2914 HQPVFDEYMKRISGFPLVQDTPENPASGGQFPQ----SKPTLYDYFWDVKDNVWKAWEWVVQPYT 2974
            .|.|..::.:....:.:           |:|..    |:.|::||..:|:...::.|..:.   .
  Fly  2674 SQDVIIDWHREFHKWWI-----------GEFKDIKLPSQGTVFDYQLNVQTLKFQPWSELA---A 2724

  Fly  2975 H-------DPQVKFSEILVPTVDNTRTNRTLSLMSEIKRPVLLVGEAGTSKTATIMQYL------ 3026
            |       |.:.....:|:.|.:..|....|.|:.:.....:|||.:|..|.|...|..
  Fly  2725 HQSLEGQIDSETPLQNVLISTAETIRLAYFLKLLIDRNLACMLVGNSGCGKGAIFRQLFGQYAND 2789

  Fly  3027 --------------------RNLNPSVNVILN----------------INFSSRTSSLDVQHTLE 3055
                                ::.||:..|::.                .:|:..|||...|..|:
  Fly  2790 QELLEVAVSAATAGDSSHQQQSGNPAGAVVVRRKASSSATPLLTTVQATHFNFYTSSEIFQKMLD 2854

  Fly  3056 AAVEKRTKDTYGPPMGK-RIACFIDDMNMPQVDDYGTQQPIALLKLFFERGGMYDRDKDLNWKKF 3119
            ..:||::...|.|...| |:..|::|:|||:||.|||.||..:::.|.:....|||.: |..|..
  Fly  2855 RPLEKKSGRCYAPSGPKRRLIYFVNDLNMPEVDAYGTVQPHTIMRQFMDYRQWYDRQR-LQLKDI 2918

  Fly  3120 KDLTFYAAMGTAGGGRNEVDPRFISMFSTYNIIFPNDESLIQIYSSIFKGHMVFVK--FQPEYML 3182
            :...|.|.|....|... :|||....|..:::..|.:::|..||.||...|:....  |..|...
  Fly  2919 RHCQFAACMNPTAGSFT-IDPRLQRHFCVFSVAPPGEDTLHHIYGSILSSHLESPSQGFTKEIRS 2982

  Fly  3183 IADMIVHMTLKLFKMVIVDLPPTPSKFHYIFNLKDLSRIFAGML--LIEPTC--------FKGL- 3236
            |..::|.:.:.|.:.|.....||..||||:|||:||:.|:.|::  :..|..        |.|.
  Fly  2983 IGSLLVRVGIALHRRVEYAFLPTALKFHYLFNLRDLTGIYQGLMNSVGAPASAGGGGASGFGGTI 3047

  Fly  3237 ----RDLIRVWRNEYTRIICDRLITDNDIANVRRNLAVEVAERFPPTFEEEHGFIDAAAAEAEAQ 3297
                .:|:|::.:|..|:..|||:...||.:.:.:    :.:.|...||
  Fly  3048 CSRPSELMRLYVHEAFRVYHDRLVDPYDIKSFKSS----IRDIFKKDFE---------------- 3092

  Fly  3298 ARLLYEPSKADIDGGEEEGEEEEEGEEAPQVILSLKDYVLRDPLLFGDFRNFTNESEPRLYEDLL 3362
                      |.|                      :|:|..:||::.   :|......:.|..|.
  Fly  3093 ----------DFD----------------------EDFVFAEPLIYS---HFAQSLVDQKYMPLK 3122

  Fly  3363 DYNSVYFLFTEILEEYCERKQKMTLVLFEDCLEHLTRVHRTLRMNRGHVLLIGVGGSGKKCITRL 3427
            .::|:|.|..|....|.|....|.||||||.:.|:.|::|.|...||:.||||||||||:.:.||
  Fly  3123 SWDSLYQLLIEAQASYNEVVGYMNLVLFEDAMIHVCRINRILESPRGNALLIGVGGSGKQTLARL 3187

  Fly  3428 AAFAAECDVFEITISRGYNEAAFREDLKVLYTIAGVKRKKVVFLFTGAQVAEEGFLELINNILTV 3492
            |||.:..:|.:|.|.||:.....||::..||...|:|....|||.:.||:.:|..|.|||::|..
  Fly  3188 AAFISSLNVSQIQIKRGFGLLDMREEIGNLYMKVGLKNLASVFLISDAQIPDESILMLINDLLAS 3252

  Fly  3493 GQVPALFPDEDKDGIVNQVRKFAEEDGVSASKDAVWGYFLRTCAENLHVVLCMSPAGDALRNRCR 3557
            |::|.||.|:..|.|.|.:|...::.|...:|:..|.||:......|.||||.||.|..||.|.|
  Fly  3253 GEIPELFNDDQLDTITNGIRNEVKQSGTLDTKENCWRYFVEKVRRLLKVVLCFSPVGQTLRVRAR 3317

  Fly  3558 NFPGLIGSTYIDWVFPWPRQALYAVAKLFLTEHRLIPASHREAIVEHV----VHVHTSIQQYSKD 3618
            .||.:|..|.|||...||:.||.:|::.||.|   |......|:|..:    .:||.::.|.|:.
  Fly  3318 KFPAIISRTAIDWFHEWPKSALESVSQKFLNE---INGILEPALVPPIGCFMAYVHGTVNQISRI 3379

  Fly  3619 YLAKLRRNNFVTPKHYLDYINTYRGLLEEKAKFITQQRSRLGEGIKKIEEASVQIDELRIIVTEQ 3683
            ||...:|.|:.|||.:|:||..||.||.:|.....::.:||..|:.|:.|.:.|:|.|:..:..|
  Fly  3380 YLQNEKRYNYTTPKTFLEYIFLYRKLLVDKNGEFAERIARLQSGMSKLAECARQVDTLKHQLAIQ 3444

  Fly  3684 KKNVAVASEECEAMLVTIESSTQKANVKKAEASEKSVEVEIKGKQIAIEKDEAEEILAEAMPALE 3748
            :..:|..:...:.::|.:.:.::|...::..|||:...|.|..:.::|:....||.|.:|.|||.
  Fly  3445 EVQLAAKNAAADKLIVIVSAESEKVKRERYIASEEEKRVRIIEEDVSIKTKMCEEDLRQAEPALV 3509

  Fly  3749 EARLALSQLEKAQITEIRSFATPPAAVQVVCECVAIL-----KGYKEINWKSAKGMMSDVN-FLK 3807
            .|:.||:.|.|..:||::||.:||.||..||..|.:|     |..::.:||::|.||..|: ||.
  Fly  3510 AAQAALNTLNKNNLTELKSFGSPPKAVVNVCAAVMVLLASNGKIPRDRSWKASKLMMVRVDQFLN 3574

  Fly  3808 SLMEMDCEALTQKQITQCRQHMKTG--NLEDMAKISVAGAGLLRFVRAVLGFFDVYKEVKPKKER 3870
            .|:..:.:.:....|...::::|..  |.:.:.:.|||.|||..:|..:..:..|:..|.||::.
  Fly  3575 DLLNYNKDNIHPNIIETLQEYLKDPEFNPDKVVQKSVAAAGLCAWVINLHRYHQVFLIVGPKQQA 3639

  Fly  3871 LDFLVEEQEVQIKLLNHLNGEIQKLEEKLNELNENYATSMKQMRALTEMMQQAERRLIASD---K 3932
            |....:|.....:.|.:|..:|..||.||.|:...:..::.:.:   ...::|::.....|   :
  Fly  3640 LQDSHQELLEARERLQYLKAKINNLEAKLAEIQAEFENAVGEKQ---RCQREADKTAFTIDLAHR 3701

  Fly  3933 LISGLTSELIRWSKEMASLGQQLIDSVGGCLISASFLAYTGAFTWEFRKAMVFDDWLEDIASLGI 3997
            |::||.:|.:||.:.:.||..::....|..|:.:|||:|.|.||..:|:.:....||.:...:..
  Fly  3702 LVNGLANENVRWKESVQSLLAKIGTLPGDILLISSFLSYVGCFTRRYREELQHKMWLPNFRKIDP 3766

  Fly  3998 PIQLPFKID--GYLTTDVEISQWSNEGLPPDELSIQNGILTMRASRFPLCIDPQLQALQWIRKRE 4060
            .|.....:|  ...:.|.:|:.|:|||||.|.:|.:|..:...::|:||.||||||.::||:.|
  Fly  3767 HIPHTEGVDTLALFSDDAQIAAWNNEGLPMDRMSTENATILQYSTRWPLMIDPQLQGIKWIKNR- 3830

  Fly  4061 FKNNLKVLSFSDSDFLKQLEMAIMYGTPVLFEDVDDYIDPVIDDILQKNIRIQGGRKFVMLGDKE 4125
            |..:|.||......||:.||.:|..|..||.|.:::.:|.|::.:|.:.: |:.|| ::.:||||
  Fly  3831 FGTDLVVLRLRQKGFLEALEKSISQGDTVLIEQIEESMDTVLEPLLSRAL-IKKGR-YLRIGDKE 3893

  Fly  4126 VDWDPSFRVYLTTKFSNPKFDPAVYAKALVINYTVTQTGLEDQLLSVVVGTERPDLEAQRESLIA 4190
            :::..|||:.|.||.:||.:.|.:.|:..:||:|||..|||:|||:.||..||||||..:..:..
  Fly  3894 IEFHASFRLILHTKMANPHYKPEMQAQTTLINFTVTPDGLEEQLLAEVVKIERPDLEQMKTEVTV 3958

  Fly  4191 QTSENKQLLQQLEDSLLRELSTSTGNMLDNVELIETLENTKTKAGVVMEQLKLAADTAADIEVLR 4255
            |.::.|..|:.|||.||..|::|..|:||:..|:..|||||.....:..:::.|..|...|:..|
  Fly  3959 QQNKFKISLKALEDELLARLASSGENVLDDHALVINLENTKRTVDEIEAKVREARVTTLQIDDTR 4023

  Fly  4256 NGYRPAAKRGAVLFFALSDMATVNSMYQYALAAYLDVFVYSLRKAVPDASLNKRLNNIIKTLTEN 4320
            |.||.||||.|:|:|.|:|::.:|.:|:::|.::::||..::..|....:..||:.::::::|..
  Fly  4024 NIYRSAAKRAAILYFVLTDLSRINPIYKFSLKSFMNVFRQAIAMAAESKNYEKRVLHLVESITLQ 4088

  Fly  4321 VYCYGCTGIFERHKLLFSFQIATKLAQRDGILLQSELDFFIKGSIALTKSERSNPCKWLSEKSWE 4385
            .|.|...|:||..||.|:..:..::......:.:.|.||.::.....|   ..:|..::...:|.
  Fly  4089 TYRYTLRGLFEADKLTFTSHMTLRILIAAEQVAKDETDFLLRFPHDPT---TLSPLDFVGRSAWG 4150

  Fly  4386 DVLKLAFDFPDIFGTLPDHF-------GRYLTEWKEWFDLENPEEVPCPGDYNIKCNAFQKLMFL 4443
            .:..|         ||.:||       ..|...|:::...:.||....||::..: ...|||..:
  Fly  4151 GIKSL---------TLIEHFYGIDKDMENYTKRWRKFMASDTPEREQFPGEWKHR-TPLQKLCII 4205

  Fly  4444 RCFRVDRIFRSINQYIVETMDEFYIMPPVVSFSAIYEQTSSTIPVCFVLSAGSDPTNDLIKL--- 4505
            |..|.||:..::.|::.:||...|.......|.||:::.::..|..|:||.|.||..|:.:.
  Fly  4206 RSLRPDRMTYAMRQFVEQTMGRSYAEIQTPPFGAIFQELNAATPAFFILSPGVDPIRDVERYGQR 4270

  Fly  4506 ------ADTIVGMSNFCHISLGQGQEKAALRLLDGAIKQG-MWLMLQNGHLLIRFVRELEKHLDR 4563
                  :||:|      :||||||||..|.:.:.||::.| .|::|||.||::.::..|||.::|
  Fly  4271 QGFHSESDTLV------NISLGQGQELLAEQAIIGALESGQQWVILQNIHLVVNWLPTLEKLIER 4329

  Fly  4564 I-----ENPHPDFRLWITTDPTP-----TFPIGILQKSLKVVTEPPNGLKLNLRSTYFKVRQERL 4618
            |     .....:|||:|:.:|.|     ..|.|||:.|||||.|||:|:..||...:....|:.|
  Fly  4330 IVLQSESKGESNFRLFISAEPAPDPQYHVIPQGILESSLKVVNEPPSGMAANLHKAWDNFSQDAL 4394

  Fly  4619 ESCSHVA-FRPLVYVLAFFHAVVQERRKYDKLGWNIAYDFNDTDFDVCTEILRTYLTRCGTGKIP 4682
            |:|:..| |:.:::.|.:||||..||||:...|||..|.||..|..:.:.:|..||.  |:.:||
  Fly  4395 ETCTQEAEFKSILFALCYFHAVAGERRKFGPQGWNKVYPFNIGDLTISSNVLHNYLE--GSNRIP 4457

  Fly  4683 WNSLKYLIGEVMYGGRVIDDFDRRITNCYMNEYMGDFLFD-EFKVF-HFYEDDNVDYCLPEEETI 4745
            |..|:||.||:||||.:.||:|||:...|:.|.:...|.| :|::. .|....|:|:
  Fly  4458 WEDLRYLFGEIMYGGHITDDWDRRLCQTYLEELLQQDLIDGDFELCPGFPAPPNLDF-------- 4514

  Fly  4746 LKEDYIAHIDKLPLVNKPDVFGLHPNAEIGYYTMAARNIWNSLIELQPQTGEGTG--GISRDDFI 4808
              |.|.::|.::.....|.::|||||||||:.|.|:..:..::.||||:..|.:.  |..|::.:
  Fly  4515 --EGYHSYITEMLPEESPLLYGLHPNAEIGFLTTASEQLLRTIFELQPRESELSSHCGAPREELV 4577

  Fly  4809 DSVAAGILKKLPPAFETWRIRKQIQMSLSPTGVVLLQELDRFNLLVVRIKKTLELLRKAIAGEIG 4873
            ..:....|.||...|....:..:::.. :|..||.|||.:|.|.|:..||::|..|...:.||:.
  Fly  4578 KIMIDDFLDKLQDEFNLQALLNRVERK-TPFVVVALQECERMNALIREIKRSLRELMLGLRGELT 4641

  Fly  4874 MDNVLDNIANSLFNGLLPAAWSKLAPATCKQLASWLEHLRLRAVQYKYWTLSGE-PLVMWLSGLH 4937
            :...::.:.:::|...:||||::||..:...|.||...|..|..:...|....: |..:||.||.
  Fly  4642 ITQEMERLDHAIFYDHVPAAWARLAYPSMLGLQSWFADLLHRIKELAGWLNDFKLPCAIWLGGLF 4706

  Fly  4938 IPQSYLTALVQIACRRNAWPLDRSTLFTYVTKFADPDDVEERPVTGCLVHGLYIEGGRFDLATNQ 5002
            .|||:|||::|.:.|::..||||..:...||| ...|||...|:.|..||.||::|..:|...|.
  Fly  4707 NPQSFLTAIMQESARKHDLPLDRMLISCDVTK-KQKDDVTLPPMEGAFVHDLYMDGASWDCQLNS 4770

  Fly  5003 LARSHPKVLVEELAILAVEPIEAHRLKLQNTYLAPVYTTSLRRNAMGVGLVFEANLATSEDLSHW 5067
            :....||.::..:.::.::.|...:.:||..|..|:|.|..|.|.    .|:..||.|.|..|.|
  Fly  4771 IVALRPKEMLCAMPVIYIKSIVQEKQELQRVYECPLYKTRSRGNT----YVWTFNLKTRERPSRW 4831

  Fly  5068 ILQGVCLTL 5076
            ||.||.|.|
  Fly  4832 ILGGVALLL 4840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc98D	NP_524541.3	DHC_N1	523..983	CDD:285571	98/514 (19%)
		DHC_N2	1798..2201	CDD:285579	127/428 (30%)
		P-loop_NTPase	2338..2565	CDD:304359	129/226 (57%)
		P-loop_NTPase	2654..2788	CDD:304359	65/134 (49%)
		P-loop_NTPase	2976..3246	CDD:304359	85/329 (26%)
		P-loop_NTPase	3378..3645	CDD:304359	112/270 (41%)
		MT	3658..3989	CDD:289543	96/341 (28%)
		AAA_9	4017..4233	CDD:289547	92/215 (43%)
		Dynein_heavy	4374..5068	CDD:281078	236/726 (33%)
CG3339	NP_001036762.2	DHC_N1	276..903	CDD:285571	141/756 (19%)
		DHC_N2	1535..1944	CDD:285579	127/428 (30%)
		P-loop_NTPase	2095..2324	CDD:304359	131/228 (57%)
		P-loop_NTPase	2409..2544	CDD:304359	66/136 (49%)
		P-loop_NTPase	2731..3061	CDD:304359	85/331 (26%)
		P-loop_NTPase	3138..3406	CDD:304359	112/270 (41%)
		MT	3419..3759	CDD:289543	97/342 (28%)
		AAA_9	3789..4001	CDD:289547	92/214 (43%)
		Dynein_heavy	4142..4832	CDD:281078	235/723 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450554
Domainoid	1	1.000	49	1.000	Domainoid score	I7912
eggNOG	1	0.900	-	-		E1_COG5245
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	P	PTHR10676
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750