DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc98D and CG9492

DIOPT Version :9

Sequence 1:	NP_524541.3	Gene:	Dhc98D / 43379	FlyBaseID:	FBgn0013813	Length:	5080	Species:	Drosophila melanogaster
Sequence 2:	NP_001287256.1	Gene:	CG9492 / 41171	FlyBaseID:	FBgn0037726	Length:	4724	Species:	Drosophila melanogaster

Alignment Length:	5141	Identity:	1463/5141 - (28%)
Similarity:	2423/5141 - (47%)	Gaps:	763/5141 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 RMESC-------DLDPKIKYIYIVRKNRREIPNFSDVSACFAQMPLYFLLGTVRGSLINSLRDDL 295
            |.|.|       ::||::::.:.:..:..::|..        |:..|...|        .:.|::
  Fly    38 RREECERKARRGEMDPRLEFTFQLLIDATQLPRH--------QLMDYIFEG--------DMLDEI 86

  Fly   296 NLVY----KSAIQFQFREPATADSQQMDSYEGQAGGSGGGGAGGPAGETGEDISSEAKESGPGLL 356
            |.::    |:.:.:.::|  |.|.:.....:....|....|....:.:|.:..:|.:....|...
  Fly    87 NQLFLPNMKNKLLWFYQE--TDDPEPTPVPDPNKPGPSRSGVASSSSKTPQGGASPSGMPPPKHK 149

  Fly   357 ELSKPSE------------FRLRALKQQKKMKEKEAAAKKAKAKKTDAE----PTEEEEEADAHK 405
            :|.....            ||:...||    ..:|...|.......||:    .|..|...:...
  Fly   150 KLFLTDGWTCAFTGVCIYIFRVNTSKQ----LPEEGFQKDLYCGVIDAKNIGLVTSIERIVEFVF 210

  Fly   406 VEA----HLSSSEEEVEIKVEKLTIGQRWEKMLNETKAKVEAEHAAEEATPPRITPIQRRLLKEI 466
            ::|    .|...||:|...:.|   ||    :|...::...|....|:...
  Fly   211 MQALAFPSLEGDEEDVSCGLIK---GQ----LLPGLRSFCSALRVCEQVCD-------------- 254

  Fly   467 EEFQSEITWTINHIVWAFSLPSSYILPGQEATEFEDAIIRVPVDPKRLDLVITYTQQQLEEVVDG 531
                       :|.|:|         .|.:..|..||:..|....|..:..     .||||.|:.
  Fly   255 -----------HHNVFA---------DGCDMFEKIDAVEEVKDMSKNQEFC-----AQLEERVNN 294

  Fly   532 WIKYLKKTMKTLTDAKL-----DDFTPMAEHRYWHKMEVELYGTLEQLKTEFVVAVLQRLTDDKS 591
            |.|.:   :|.|.:::.     |...|..|..||.|...:....|..|:.:.|...|..|....|
  Fly   295 WTKGI---LKILGESEQLRKENDHSGPQDELEYWKKRGAQFSQLLAHLQDKEVQFTLHCLFLAGS 356

  Fly   592 PVLDEWQAVVEKTEARFKLAKENSDYLGTIID-----YLEKVRSYESFKMVVLQIPNIMVGLRHI 651
            .::.:|:....|....:..|::||.::..:..     ||:...|.:...:.:||.      :|.|
  Fly   357 RIIKQWKETDRKITFCYNEARDNSKFIQAMETCCHSLYLDDPVSMKESILSLLQT------VRLI 415

  Fly   652 WTMSSHYCRDPEMQVLLCQISNVFVQKVKSIINF---ENIFKYSATYTYETATNCANLLRCWKQA 713
            :::|..|........|:.:|:|..::..||.|..   |.|:...........:||..|...:.:.
  Fly   416 YSVSQFYNTSERTSALMVKITNQMIETCKSYITCRCKETIWSQDRNVIRTKLSNCIKLNHIYHET 480

  Fly   714 YKLSRQ-----HIEDSGAGSRWEFDR-----------VALFNEVNHIHRVAVDIAYVGRVFVQYE 762
            |...|:     :....|....:.|.:           :::||.::                 .|.
  Fly   481 YYTVREQPFLPNQTPFGFSENFVFGKFDTFCERLSKIISMFNLID-----------------DYN 528

  Fly   763 NLFGHRLKACIADPSIVD--NLMRKVYRMLDDLIKSVDYDMFRPGNWENWEYSLELFNKRLDNVE 825
            :||..||:..:...::.|  |...:..:.    :.|..||.....| .::....|.|..:.::::
  Fly   529 HLFERRLEGLLLGEALEDASNHFEEAKKE----VTSRKYDYLDHRN-SDFNIDFERFIHKTNSLK 588

  Fly   826 NEAKNVIDQSINSLLSSEKGLDLVVNAMNIDTRATLQEFVATKHENLLRFFVTEINAVERVFTKL 890
            :....:|::..:::..:.:.:..:|....:..:..|.. :..|:..:||:...|::.:.:.|.|.
  Fly   589 DTIATLIEKDFDTVWETPQCIRFLVRFEKVSEKIPLTR-MDEKYTRILRYVEKEVDRILKTFRKQ 652

  Fly   891 KKSPPMAKHQPAKISAIFWARLLG---KKLKTSVLAFKRVEDEPAIKNSFLKRSSFKQYFELMTV 952
            :..||:|::.|.....|.|.|.|.   .:|..:|:....:...|..|:..::      |..::.:
  Fly   653 RDDPPLARNFPPIAGRIHWCRALSLHITELMDAVMEHVVLSSLPMAKDLDVR------YHNVLGI 711

  Fly   953 MFQFEKVLFENFIQNATYLVNTTNRSNVLRIRICKESTMSYISEAVQTLKAKPRPELQMTSDRRV 1017
            :.::|..:...::                                                |:.|
  Fly   712 LQEYEDEIVSIWL------------------------------------------------DQDV 728

  Fly  1018 TPVKSSNLMPVQSEAFSAYSVADSAGTEISSESENEGLLVGDTSQKKLMCRINRLTVLVAMIMWM 1082
            :...:..|.|:.|                         |.||    ||...::....|:.....|
  Fly   729 SVADACLLQPLLS-------------------------LQGD----KLFVNLHPTIPLLIREAKM 764

  Fly  1083 VSNTRKANIQLQECTAFIKMVKDKKPKDVTAMDRHCVRTCELLQRAESQYLLPIWRELVGEKTLI 1147
            ::   |.:|:|....|             |.|.|             .||.:.|...|   ..||
  Fly   765 LA---KLDIELPIVAA-------------TLMSR-------------QQYFITIQDSL---NCLI 797

  Fly  1148 EYDMDFVVNLKRDVFDVLFEAQQFEHLGFTLPAVLR-TAIMKKDLLFKDY--ERMTEVVDRYRSI 1209
            :..:..|..:|.:|..:.            ||.::| ||::|..|...::  :..||..:|.:..
  Fly   798 KMFLSTVRAVKLEVRPLF------------LPQLVRLTAMLKPGLHTINWTNQNWTEFYERCKQA 850

  Fly  1210 INNLSMSEVIFLRGH-IY------------DTELFIQMGVGRYTWTSFNIGKFCDQINSQLRKLT 1261
            |.:.   :|:..|.| ||            |..|.| :......||   :.:|.::.....||..
  Fly   851 IESF---DVLVARVHDIYSNRILHVLMWMQDVSLQI-LPADDEIWT---VDEFLERSEEACRKAA 908

  Fly  1262 SIVSQINFIRLDLRSRIDMIKSFNLFNLDDELKVEDTSRSSGESYLQDRKNPSQRFKSVTG-ETI 1325
                      ::|..:..|:..    .:::.|.:.|.:.::              ||.:.| :.|
  Fly   909 ----------IELNRKSQMVSE----AVEEVLSLVDRATAA--------------FKEIAGDDVI 945

  Fly  1326 TMFSV-----EKDVPADEKAEQACGSG----------------------IYPC-QGYFELLEASR 1362
            |:|..     :.......|.|...|.|                      ::.| :....||..:.
  Fly   946 TLFDAATPKGDNSGSGGRKPEDGGGGGGGAAAPSTSGGGGGGQQQDWSILWSCFENPLSLLSTTE 1010

  Fly  1363 N----------RKAAQMKKLYD-SLGPVLVKLESLVLGTFSGR--SDRMKTYYEYWEGETFKCIV 1414
            :          ....:|::.|. .:..||:|:....|.|...|  :|..:|.::
  Fly  1011 SLPKGMQDMVCNAVVEMRRYYSRKVIDVLIKVIRAALDTLRRRFIADENETVFK----------- 1064

  Fly  1415 DMTYQNLKCYINRLLSNKPMFEVNAVLLMSEIVLEPSVQELQNTIVTATKDYISRLRIFTRWMTG 1479
                             ||:|.::|.|.:..:|::|::.|||:.:|||.|:.....:...:|.:|
  Fly  1065 -----------------KPVFALHAQLQIPHVVIKPNLDELQDILVTAGKNITGIAKGVAQWSSG 1112

  Fly  1480 T--------------------------------CIAC---PLVEMGKQFKYNYTYYEDVIQIRSI 1509
            .                                |:|.   |  :|....|   ::|..::..:.:
  Fly  1113 KDPPQVSMTVQPRVGRNHNESTGGGKSRRRKIYCLASEERP--QMPHMLK---SFYSAIMDNKEV 1172

  Fly  1510 VDLVINIHDLASRVANEARGFVSQFRKYFNLW---------------AFEKSFICQKFLEKQVTL 1559
            ...|..:......|..|.:.::.:::.|..||               .||.:..|...|:..: |
  Fly  1173 AKAVNQLASCTKNVKPEIQTYIKRWKPYHFLWKNDRTTRQLMEFGLQEFETTLRCLSDLDANL-L 1236

  Fly  1560 IEIDEKFTFYSSIVETLANTRKFQDIKCVRINLEPLLASITQHAQDWCTTLGEELLRHVNDNMRA 1624
            :|.|         :|...        :||.:..|.|...:....:.....:|:.:.:.....|..
  Fly  1237 VEPD---------MEVFG--------QCVAVYNEKLKYGLAIEIKSCNHKIGQAMKKKYKKEMDY 1284

  Fly  1625 MRNEVKTLSLNLNKTTRELEDFKLVMTTIGTVQSSTLTNEQKIHEMQETFTILSEHKIMFPYEDM 1689
            :...:..:...|::..|:|:|.:::|.|:|.::...:..|.:|..::|.|.:|:.:::....|..
  Fly  1285 VYAVINEMDRKLDRPIRDLDDVRMIMETLGKIREQEVDMELRIDPIEEAFNVLTRYEVQVEREQF 1349

  Fly  1690 LMAHHLEKRWKRLFLSALYRYEKLQPIKQKFADMTSVEIDEFCDDLAEFIKDYDENGPGSVGAEL 1754
            .:..:|...::.|...||....||..::..|.|.....:|.|..|...::.:|...||...|...
  Fly  1350 DLVDNLRATFQNLLAGALQAQVKLLDMQPAFQDDLRTNLDNFKQDKISYVTEYRTAGPMQAGLTP 1414

  Fly  1755 ERGVRLMDPYGQKIAERESRREELANAERLFDMAMVDYHEFARVQTEFEGLQQLYKLYKAQKYAR 1819
            ......:..:..:......|.:...:.|.||.:...||.|..:::.|...||:|||||.......
  Fly  1415 REASDRLILFQNRFEGMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNLLQKLYKLYNDVIDRV 1479

  Fly  1820 EGWGKTLWADLDPNVLTEGVESYLKEF----RKFTKAVRTLPVGVQLEIHMKQFKGTVPLMVSLK 1880
            ..:....|.::|    .|.:.:.|.||    ||..|.::..|....|:..:..|....||:..:.
  Fly  1480 SSYYDIPWNEVD----IEEINNELMEFQNRCRKLPKGLKEWPAFHALKKTIDDFNDMCPLLELMA 1540

  Fly  1881 HEALRERHWLQLMEKTGQYFDMSPARFTLENMFAMQLHKYQEIAEQILTNAIKELQIERGVQAVI 1945
            ::|::.|||.::|:.|...|:.....|:|:|:....|.|::|..|.|..:|:||..||..::.|.
  Fly  1541 NKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDIEDICISAMKEKDIEAKLKQVT 1605

  Fly  1946 ETWA--SMAFKTFKHFKGSDDRGWVLGPVD---EIMQILEDNAMNLQSMGASQFIGPFLETVNKW 2005
            ..|:  .:.|.:|      ::||.:|...|   |.:..|||:.|.|.|:.::::..||.:.:.:|
  Fly  1606 NEWSVHELQFMSF------NNRGELLLRGDTTAETIGQLEDSLMVLGSLLSNRYNAPFRKQIQQW 1664

  Fly  2006 ERTLALISEIIDEWLVVQRKWLYLEGIFIGGDIRTQLPEEARKFDDIDKSYRRIMVDCAKNPLVV 2070
            ...|:..:||::.||:||..|:|||.:|:||||..|||:||::|..||||:::||....:.|.||
  Fly  1665 VYDLSNSNEILERWLLVQNMWVYLEAVFVGGDIAKQLPKEAKRFSKIDKSWQKIMQRAHETPGVV 1729

  Fly  2071 PFCTVPGRLVE-IQGLGIGLENCQKSLNEYLDSKRRIFPRFYFISTDELLSILG-SSEPSAVQNH 2133
            ..|.....|.: :..|...||.|||||:.||:.||.:||||:|:|...||.||| :|:...:|||
  Fly  1730 ACCVGDDLLKQLLPHLQEQLEICQKSLSGYLERKRMMFPRFFFVSDPALLEILGQASDSHTIQNH 1794

  Fly  2134 IIKMYDNIKSLRLVKEGSQTIVTGMISSEGEVMEFRHSARAAGRVEYWMNDVLDEMRRSNRFINK 2198
            ::.::||.||::. .:.....:..:||||||:::...:.||.|.||.|:..:|...:.|...|.:
  Fly  1795 LLNIFDNTKSVKF-HDVEYNKMMAIISSEGEMIQLDRAIRAEGSVETWLTQLLVTAQASLHSIIR 1858

  Fly  2199 TAIYDFGTDLQISRPDWLMNYQGMVGLAASQVWWTAEVEEAFDQAQNHGNMRAMKDFLGKNNYQI 2263
            || |....|...:...:|......:||...|:.||.:.|.|..:.      |..|..:..||..:
  Fly  1859 TA-YATINDPNFTLLSFLEKAPAQIGLLGIQMVWTRDAEMALMRG------RERKVMMETNNKFL 1916

  Fly  2264 E---ELVLKVRSNLSRNDRLKFKAQCTVDVHARDIIDNFVRDNVLDASEFSWESQLRFYWIKFYD 2325
            |   .|:.:...||::.:|..|:...|:.||.|||.|...|.|:..|::|.|..|.|||:.:..|
  Fly  1917 EMLNTLIDQTTRNLTKRERTNFETLITIHVHQRDIFDILCRMNIKSANDFEWLKQCRFYFKEDLD 1981

  Fly  2326 NLHVLQCSGSFDFGYEYMGLNGRLVITPLTDRIYLTITQALLMNLGGAPAGPAGTGKTETVKDLA 2390
            ...:.....:|.:..||:|...||||||||||.|:|:.|||.:::||||.|||||||||||||:.
  Fly  1982 KTWISVTDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQALTLSMGGAPCGPAGTGKTETVKDMG 2046

  Fly  2391 KAMGLLCVVTNCGEGMDYRAVGTILSGLVQCGAWGCFDEFNRIDISVLSVISTQLQTIRNGLIRK 2455
            |.:....||.||.:.||||.:|.|..||.|.|:||||||||||::.||||.:.|:..:......|
  Fly  2047 KTLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSVAAQQVAVVLTAKKEK 2111

  Fly  2456 LDRFVF-EGVEIHLDPKCGVFVTMNPGYAGRTELPESVKALFRPVTCIKPDLELICLISLFSDGF 2519
            ...|:| :|..|.::|:.|:|:|||||||||.||||::|..||.|..:.||.::|..:.|.|.||
  Fly  2112 RKTFLFTDGDTIEMNPEFGIFITMNPGYAGRKELPENLKIQFRTVAMMVPDRQIIIRVKLASCGF 2176

  Fly  2520 LTAKVLAKKMTVLYSLAQAQLSKQCHYDWGLRSLNSVLRMAGVMKRQSEDLPEAVVLMRVLRDMN 2584
            |....||:|...||.|.:.||:||.|||:|||::.||||..|..||::....|:.::||||||||
  Fly  2177 LENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAAKRRNSKDTESTIVMRVLRDMN 2241

  Fly  2585 FPKFVFEDVPLFLGLIKDLFPGIDCPRIGYPDFNAAVRHVLVNDGYILLPDQEDKVVQMYETMMT 2649
            ..|.:.:|.|||:.|:.||||.....:..||:..||:.........:..|....|::|:|||...
  Fly  2242 LSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEAAILQQTDEASLVYHPPWVLKLIQLYETQHV 2306

  Fly  2650 RHSTMLVGPTGGGKTVVINALVKAQTHMGLPTKCLVLNPKACSVIELYGFLDMETRDWIDGLFSN 2714
            ||..|.:||:|.|||..|:.|:||.|.||...:.:.:||||.:..:::|.||:.|.||.||:||.
  Fly  2307 RHGIMTLGPSGAGKTTCIHTLMKAMTQMGDNHREMRMNPKAITAAQMFGRLDVATNDWTDGIFSA 2371

  Fly  2715 IFREMNKPIEREERRYACFDGDVDALWIENMNSVMDDNKLLTLANGERIRLENYCALLFEVGNLN 2779
            ::|:..| ::..|..:...||.||::||||:|||:||||.||||||:|:.:.....::||..|::
  Fly  2372 LWRKTLK-LKAGEHVWLVLDGPVDSIWIENLNSVLDDNKTLTLANGDRLTMAPTVKIIFEPHNID 2435

  Fly  2780 YASPATVSRAGMVYVDPKNLRYSPFWQRWVLTRPEPQRELLNDFFEKIITQSIAFILEGLDGTTQ 2844
            .||||||||.||||:....|...|..|.|:..|...::...:|.|::.       .:|..:...|
  Fly  2436 NASPATVSRNGMVYMSSSGLDSRPIVQAWLKNRAPGEKSTFSDLFDQT-------FVEVYNWGVQ 2493

  Fly  2845 GNPLKLVIMQTDLNMVTQFCNLYDALLPNYVMDSKNYDEPVQQNYNTDSLECCFLQAVYGSMGAC 2909
            ...|::.::|  .|:|.|...:.:.|:|     .|..||   |..:..|.|         |..|.
  Fly  2494 MVKLQMPVLQ--CNIVQQMLFILEGLIP-----VKKEDE---QAVSMSSKE---------SHDAN 2539

  Fly  2910 LVEKHQPVFDEYMKRISGFPLVQD--------------TPENP----------ASGG-------- 2942
            ...:||...:|..::..|..:|:|              |||:.          ..||
  Fly  2540 KRLEHQKHVEEARRQSIGSQIVEDLPPETSIEEKEDTCTPEHLHRLYIFALAWGLGGYLSTSDRQ 2604

  Fly  2943 --------QFPQ--------SKPTLYDYFWDVKDNVWKAWEWVVQPYTHDPQVK---FSEILVPT 2988
                    .|||        .:.|::|:|.. ...||::|:.:|.||.: |::.   :..||||.
  Fly  2605 RMNLFVKESFPQLDYPKGSAHENTIFDFFVS-PAGVWQSWKTLVTPYMY-PELSTPDYLSILVPI 2667

  Fly  2989 VDNTRTNRTLSLMSEIKRPVLLVGEAGTSKTATIMQYLRNLNPSVNVILNINFSSRTSSLDVQHT 3053
            |||.|.:..:..::..:|.|:::||.||.||..:..:::.:|....:..:.||||.||....|.|
  Fly  2668 VDNVRIDYLIGTIANQERAVMVIGEQGTGKTVIMKNFMKKMNVESYMGRSFNFSSATSPYQFQRT 2732

  Fly  3054 LEAAVEKRTKDTYGPPMGKRIACFIDDMNMPQVDDYGTQQPIALLKLFFERGGMYDRDKDLNWKK 3118
            :|:.||||...|:|||.|:::..||||:|:|:::::|.|....:::...:..|.|..:|..::..
  Fly  2733 IESYVEKRVGVTFGPPGGRKLIVFIDDINLPEINEWGDQITNEIVRQSMDMKGFYSLEKPGDFTT 2797

  Fly  3119 FKDLTFYAAMGTAGGGRNEVDPRFISMFSTYNIIFPNDESLIQIYSSIFKGHMVFVK-FQPEYML 3182
            ..|:.:.||||..|||||::..|....|..:|...|:::|:.:|:..|.:||....: |.||...
  Fly  2798 IVDVQYVAAMGLPGGGRNDIPSRLKRQFCVFNCNIPDNDSIDKIFRVIGEGHYNAKRGFVPEIRS 2862

  Fly  3183 IADMIVHMTLKLFKMVIVDLPPTPSKFHYIFNLKDLSRIFAGMLLIEPTCFKGLRDLIRVWRNEY 3247
            :...::.:|..|::.....|.|||:||||:|:|:|||||:.||:....|.......|:.:|::|.
  Fly  2863 LVKKLIVVTRHLWQRTREKLLPTPAKFHYVFSLRDLSRIWQGMVGTLSTVITSESVLMALWKHEC 2927

  Fly  3248 TRIICDRLITDNDIANVRRNLAVEVAERFPPTFEEEHGFIDAAAAEAEAQARLLYEPSKADI--D 3310
            ||:..||..|..|.......||..|.|..               .::.:| .:|..|...|.  |
  Fly  2928 TRVFADRFTTFQDKEWFGSELACLVREEL---------------GDSHSQ-MILPNPVFVDFMRD 2976

  Fly  3311 GGEEEGEEEEEGE-EAPQVILSLKDYVLRDPLLFGDFRNFTNESEPRLYEDLLDYNSVYFL--FT 3372
            ..|..|||.|:.: |.|:|.                        ||....::|....|.||  |.
  Fly  2977 APEPTGEEGEDTDMELPKVY------------------------EPVHSHEVLRERLVMFLAQFN 3017

  Fly  3373 EILEEYCERKQKMTLVLFEDCLEHLTRVHRTLRMNRGHVLLIGVGGSGKKCITRLAAFAAECDVF 3437
            |::     |...|.||.|.|.:.||.::.|.:|..||.|:|:|||||||:.:|:||:|.|....|
  Fly  3018 EMV-----RGSGMDLVFFPDAMLHLVKISRIIRHPRGSVMLVGVGGSGKQSLTKLASFIAGYKTF 3077

  Fly  3438 EITISRGYNEAAFREDLKVLYTIAGVKRKKVVFLFTGAQVAEEGFLELINNILTVGQVPALFPDE 3502
            :|.::|.||.|.|.||||:||...||:.|...||||...:.||||||.:||||:.|.:..||..:
  Fly  3078 QIALTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDMDIKEEGFLEYLNNILSSGVISNLFSRD 3142

  Fly  3503 DKDGIVNQVRKF--AEEDGVSASKDAVWGYFL-RTCAENLHVVLCMSPAGDALRNRCRNFPGLIG 3564
            ::..||.::...  .|....:|:.::|..:|| |||. ||||..|.||.|:..|:|.:.||.|:.
  Fly  3143 EQAEIVQELTPVMKRENQRKTATPESVMDFFLARTCT-NLHVAFCFSPVGETFRSRVQRFPALVS 3206

  Fly  3565 STYIDWVFPWPRQALYAVAKLFLTEHRLIPASHRE-----AIVEHVVHVHTSIQ----QYSKDYL 3620
            ...|||:.|||:.||.:||:.||        ||.|     |:.|.:|:...|||    :.|::|.
  Fly  3207 GCTIDWLHPWPKDALVSVARHFL--------SHFEIECTPAVKEELVNALGSIQDIVAETSQEYF 3263

  Fly  3621 AKLRRNNFVTPKHYLDYINTYRGLLEEKAKFITQQRSRLGEGIKKIEEASVQIDELRIIVTEQKK 3685
            .:.||...||||.||::|..|:.:.:.|.:.:.....::..|::|::|||..::.|:..:...::
  Fly  3264 QRFRRATHVTPKSYLNFIAGYKNIYQMKQQELRDGVEKMDTGLEKLKEASASVEILKKDLVVMEE 3328

  Fly  3686 NVAVASEECEAMLVTIESSTQKANVKKAEASEKSVEVEIKGKQIAIEKDEAEEILA--------- 3741
            .:..||:..|::||              |.:|::::.||...|:.|.||:||.::|
  Fly  3329 ELVEASKNAESVLV--------------EVTERAMQAEIVKNQVLIVKDKAEALVACIAHEKALA 3379

  Fly  3742 -----EAMPALEEARLALSQLEKAQITEIRSFATPPAAVQVVCECVAILKGYK------------ 3789
                 .|.||||||..||:.::.|.|..:|....||..:..:.:||.||...|
  Fly  3380 EEKLEAAKPALEEAENALNTIKPAHIATVRKLGRPPHLIMRIMDCVLILFKRKLHPCIPDAGTPC 3444

  Fly  3790 -EINWKSAKGMMSDVNFLKSLMEMDCEALTQKQITQCRQH--MKTGNLEDMAKISVAG--AGLLR 3849
             :.:|:.:..||:...||..|.....:.:..:.|...:.:  |:..|: |||: .|.|  ||||.
  Fly  3445 PKPSWQESLKMMASATFLLQLQNYPKDTINDEMIDLLQPYFRMEDYNM-DMAR-RVCGDVAGLLS 3507

  Fly  3850 FVRAVLGFFDVYKEVKPKKERLDFLVEEQEVQIKL-LNHLNG---EIQKLEEKLNELNENYATSM 3910
            :.:|:..|..|.|||.|.|..|..    ||.::|| ::.|.|   ::::.||.|..:.:.|..::
  Fly  3508 WTKAMSFFHSVNKEVLPLKANLTM----QEARLKLAMDDLAGAEEQLREREEALQAVKDQYDKAV 3568

  Fly  3911 KQMRALTEMMQQAERRLIASDKLISGLTSELIRWSKEMASLGQQLIDSVGGCLISASFLAYTGAF 3975
            .:.:.||:......|::.|:..||:||:.|..||:.:......||...||..|::..||:|.|.:
  Fly  3569 GEKQRLTDAANVCLRKMTAATALINGLSDEKHRWTNQSKEFKIQLGKLVGDVLLATGFLSYCGPY 3633

  Fly  3976 TWEFRKAMVFDDWLEDIASLGIPIQLPFKIDGYLTTDVEISQWSNEGLPPDELSIQNGILTMRAS 4040
            ..||| |.:...|:..:....||......|...|.....:|:|:.:|||.||||:||.::..::|
  Fly  3634 NQEFR-ANLIKTWMGILKQKNIPFTTGLNIINMLVDSSTVSEWTLQGLPNDELSVQNALIATKSS 3697

  Fly  4041 RFPLCIDPQLQALQWIRKREFKNNLKVLSFSDSDFLKQLEMAIMYGTPVLFEDVDDYIDPVIDDI 4105
            .:||.:|||.|...||:.:|.:|.|::.|.:...|...||.::..|.|:|.|||...:|||||::
  Fly  3698 SYPLLVDPQTQGKIWIKCKEDRNELQITSLNHKYFRTHLEDSLSLGRPLLIEDVGIDLDPVIDNV 3762

  Fly  4106 LQKNIRIQGGRKFVMLGDKEVDWDPSFRVYLTTKFSNPKFDPAVYAKALVINYTVTQTGLEDQLL 4170
            |:||....|..:.|::||||.|..|.|.:|:|||..||.|.|.|.||..:|::|||..|||||||
  Fly  3763 LEKNFIKSGSIEKVLVGDKECDVMPGFMLYITTKLPNPAFSPEVSAKTSIIDFTVTMRGLEDQLL 3827

  Fly  4171 SVVVGTERPDLEAQRESLIAQTSENKQLLQQLEDSLLRELSTSTGNMLDNVELIETLENTKTKAG 4235
            ..|:..|:.||||:|.:|.....:|::.:::||.:||..||:|.|:::|:..|||.|..|||.|.
  Fly  3828 GRVILMEKSDLEAERVALFETVMQNQRNMKELEANLLLRLSSSQGSLVDDEALIEVLRVTKTTAE 3892

  Fly  4236 VVMEQLKLAADTAADIEVLRNGYRPAAKRGAVLFFALSDMATVNSMYQYALAAYLDVFVYSLRKA 4300
            .|.::||::..|...|...|..:|..||||::|:|.:.:|:.||:|||.:|..:|.:|.:|:.|:
  Fly  3893 EVNQKLKISEVTERKIMKAREEFRAVAKRGSILYFLIVEMSNVNAMYQNSLKQFLVIFNHSITKS 3957

  Fly  4301 VPDASLNKRLNNIIKTLTENVYCYGCTGIFERHKLLFSFQIATKLAQRDGILLQSELDFFIKGSI 4365
            ...:...:|:|.|::.||..||.:....::||||.||:..:|.|:...:|.:...|...||||..
  Fly  3958 TKSSVTEERINIILRYLTYEVYKFTNRSLYERHKQLFTLMLAIKIDYHNGNISHEEFLTFIKGGA 4022

  Fly  4366 AL-TKSERSNPCKWLSEKSWEDVLKLAFDFPDIFGTLPDHFGRYLTEWKEWFDLENP--EEVPCP 4427
            :| ..:....|.:|:.:.:|.::::::  ..:.|.|:.........:|:.|::.|.|  ||:||
  Fly  4023 SLDLNAVTPKPFRWILDITWLNLVEIS--KLETFSTVLQVIELNEKDWRCWYECEKPENEEIPC- 4084

  Fly  4428 GDYNIKCNAFQKLMFLRCFRVDRIFRSINQYIVETMDEFYIMPPVVSFSAIYEQTSSTIPVCFVL 4492
             .||...:.|:||:.:|.:..||......:||.|::...|....::....::.::....|...:|
  Fly  4085 -GYNAILDGFRKLLLIRSWCPDRTISQAKKYIEESLGPEYSEMQILDLEEMWLESEPRTPFVCLL 4148

  Fly  4493 SAGSDPTNDLIKLA--DTIVGMSNFCHISLGQGQEKAALRLLDGAIKQGMWLMLQNGHLLIRFVR 4555
            |.|||||..:..||  .:||..|    :|:|||||..|.:::..::..|.|::|||.||.:.|..
  Fly  4149 SIGSDPTTQIGALAKQKSIVLKS----VSMGQGQEYHARKMIIESMAIGGWVLLQNVHLSLPFCS 4209

  Fly  4556 ELEKHLDRIENPHPD--FRLWITTDPTPTFPIGILQKSLKVVTEPPNGLKLNLRSTYFKVRQERL 4618
            |:...|  :|:.|.|  ||:|:||:|...||||:||.:||...|||.|::.:|:.:|....|:.|
  Fly  4210 EIIDML--VESEHIDDSFRMWVTTEPHNEFPIGLLQMALKFTNEPPQGIRASLKRSYQSFTQDFL 4272

  Fly  4619 ESCSHVAFRPLVYVLAFFHAVVQERRKYDKLGWNIAYDFNDTDFDVCTEILRTYLTRCGTGK-IP 4682
            :..|...:.||:|.:||.|.:||||||:..|||||.|:||..||....:.::.:|......| :.
  Fly  4273 DYTSATQWPPLLYTVAFLHTIVQERRKFGPLGWNIPYEFNQADFAASVQFIQNHLDEMDPKKGVS 4337

  Fly  4683 WNSLKYLIGEVMYGGRVIDDFDRRITNCYMNEYMGDFLFDEFKVFHFYEDDNVDYCLPEEETILK 4747
            |.:|.|:||||.|||||.||||:|:...:.:.:..:.|..  ..|.||:    .|.:|..:::
  Fly  4338 WQTLVYMIGEVQYGGRVTDDFDKRLLTTFTSVWFCEPLLS--NSFEFYK----GYKVPGTKSL-- 4394

  Fly  4748 EDYIAHIDKLPLVNKPDVFGLHPNAEIGYYTMAARNIWNSLIELQPQTGEGTGGISRDDFIDSVA 4812
            :.:|.:|:.||..:.|:|||||.||:|.|...:|:.|.::::.:||:.|.|.||.:|:..:..:|
  Fly  4395 QGFIDYINSLPAYDTPEVFGLHSNADITYQINSAKGILDTILSVQPKEGGGGGGETRESIVYQLA 4459

  Fly  4813 AGILKKLPPAFETWRIRKQIQMS--LSPTGVVLLQELDRFNLLVVRIKKTLELLRKAIAGEIGMD 4875
            ..:|:|||..:..:.:|:.:...  |.|..:.|.||:||...::.|:...|..|:.||.|.|.|.
  Fly  4460 DDMLRKLPAQYNAYEVRENLTRMGILLPMNIFLRQEIDRMQRVIKRVHTCLCDLKLAIDGTIVMS 4524

  Fly  4876 NVLDNIANSLFNGLLPAAWSKLAPATCKQLASWLEHLRLRAVQYKYWTLSGEPLVMWLSGLHIPQ 4940
            ..|....:::::..:|..|.|::..: ..|..|...|..|..|::.|..:..|.|.|::|...||
  Fly  4525 PALKESLDAMYDARIPETWMKISWES-TTLGFWYTELLERNGQFRTWISTDRPKVFWMTGFFNPQ 4588

  Fly  4941 SYLTALVQIACR-RNAWPLDRSTLFTYVTKFADPDDVEERPVTGCLVHGLYIEGGRFDLATNQLA 5004
            .:|||:.|...| ...|.||...|...:|:: :.:|:.|.|..|..||||::||...|..:.:|.
  Fly  4589 GFLTAMRQEVTRAHKGWALDSVVLQNQITRY-NKEDITEYPTEGVYVHGLFLEGASLDRRSGKLI 4652

  Fly  5005 RSHPKVLVEELAILAVEPIEAHRLKLQNTYLAPVYTTSLRRNAMGVGLV-FEANLATSEDLSHWI 5068
            .|..|||.|::.::.:..|.....|....|..|:|....|.:...||.: ||    |..:..||.
  Fly  4653 ESKMKVLYEQMPVIYIYAINTTAGKDPKLYECPIYRKPQRTDLKYVGSIDFE----TEFNPKHWT 4713

  Fly  5069 LQGVCL 5074
            |:||.|
  Fly  4714 LRGVAL 4719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc98D	NP_524541.3	DHC_N1	523..983	CDD:285571	88/493 (18%)
		DHC_N2	1798..2201	CDD:285579	140/413 (34%)
		P-loop_NTPase	2338..2565	CDD:304359	119/227 (52%)
		P-loop_NTPase	2654..2788	CDD:304359	62/133 (47%)
		P-loop_NTPase	2976..3246	CDD:304359	91/273 (33%)
		P-loop_NTPase	3378..3645	CDD:304359	115/278 (41%)
		MT	3658..3989	CDD:289543	102/365 (28%)
		AAA_9	4017..4233	CDD:289547	95/215 (44%)
		Dynein_heavy	4374..5068	CDD:281078	227/704 (32%)
CG9492	NP_001287256.1	DHC_N1	283..843	CDD:285571	124/723 (17%)
		DYN1	1178..4372	CDD:227570	1112/3343 (33%)
		DHC_N2	1458..1861	CDD:285579	141/414 (34%)
		P-loop_NTPase	1994..2222	CDD:304359	119/227 (52%)
		P-loop_NTPase	2309..2444	CDD:304359	62/135 (46%)
		P-loop_NTPase	2662..2926	CDD:304359	90/263 (34%)
		P-loop_NTPase	3025..3287	CDD:304359	114/270 (42%)
		MT	3300..3646	CDD:289543	102/366 (28%)
		AAA_9	3674..3890	CDD:289547	95/215 (44%)
		Dynein_heavy	4031..4713	CDD:281078	227/705 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450587
Domainoid	1	1.000	84	1.000	Domainoid score	I5259
eggNOG	1	0.900	-	-		E1_COG5245
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D11510at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	P	PTHR10676
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.750