Protein Alignment Dhc98D and sac

DIOPT Version :10

• Sequence 1: NP_524541.3
• Gene: Dhc98D / 43379
• FlyBaseID: FBgn0013813
• Length: 5080
• Species: Drosophila melanogaster
• Sequence 2: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Alignment Length: 1334
• Identity: 214/1334 - (16%)
• Similarity: 411/1334 - (30%)
• Gaps: 587/1334 - (44%)

  Fly   370 KQQKKMKEKEAAAKKAKAKKTD--AEPTEEEEE-------------------------------- 400
            :::::.::.....:.|||..||  .:||||:..
  Fly   122 RRRRQYQKINLVNELAKAGLTDDVLQPTEEQYNVMSEFAFPHKFPLSYFDDSNFDINSPAAWFEL 186

  Fly   401 ---ADAH-----------------------KVEAH--------LSSSEEEVEIKVEKLT---IGQ 428
               .|||                       .|.||        |.|.|:.....|.||.   :.:
  Fly   187 GVVGDAHYPLPAKAYLPYNQSLLNCQWGMAAVTAHHEDSDLWTLLSLEDGCTYTVPKLQFMFMAE 251

  Fly   429 RWEKMLNETKAKVEAEHAAEEATPPRITPIQRRLLKEI-------EEFQSEITWTINHIVWAFSL 486
            ...|.:...:|.|...|..|:.           :|.|:       |:.:|.:.::..
  Fly   252 DPHKYIKRLQAAVHERHKGEQL-----------MLMELIVDCVLHEDIESTVFYSFK-------- 297

  Fly   487 PSSYILPGQEATEFEDAIIRVPVDPKRLDLVITYTQQQLEEVVDGWIKYLKKTMKTLTDAKLDDF 551
            |...:|...:.:|.....:|..|:.....|:..|..:|       :|..:.|......:..|.:|
  Fly   298 PIESVLQAAKVSEQCKRRLRSEVNLVFERLMALYELEQ-------FILKMPKEFPQFRNINLKEF 355

  Fly   552 TPMA---EHRYWHKMEVELYG-TLEQLKTEFVVAVLQRLTDDKSPVLDEWQAVVEKTEARFKLAK 612
            .|.:   :.....::|::..| |:::.:.:::.|.|              ...|...||...:|.
  Fly   356 LPRSFAVDVSGKERLELQALGITMQEKRYDYLKASL--------------FYCVGGIEAMAGVAI 406

  Fly   613 ENSDYLGT-------------IIDYLEKVRSYESFKMVVLQI--PN-----IMVGLR-------- 649
            | ..|:.|             ::|:|:...::.......|::  |.     |.|.||
  Fly   407 E-CQYIETLSIFICSFSKPLALVDFLQAQEAHSDNVATFLKVYWPQQLTTVITVVLRALGKGWLD 470

  Fly   650 ---HIWTMSSHYCRDPEMQVLLCQISNVFVQKVK-------------SIINFENIFKYSATYTYE 698
               :.||:           .|:|:||. |:.:||             |::||.:.
  Fly   471 ISLNTWTV-----------YLMCKISR-FILQVKFRMQESMEVLLETSLMNFSHF---------- 513

  Fly   699 TATNCANLLRCWKQAYKLSRQHIEDSGAGSRWEFDRVALFNEVNHIHRVAVDIAYVGRVFVQYEN 763
            ....|...|.. |..||.:..:|:     :.:.|.:        .:..:.:.|:...:||.
  Fly   514 VCDPCLQFLEL-KSNYKWTNNYID-----TEFPFQK--------PVFAMTLGISEDRKVFY---- 560

  Fly   764 LFGHRLKACIADPSIVDNLMRKVYRMLDDLIKSVDYDMFRPGNWENWEYSLELFNKRLDNVENEA 828
                                            |.|.|.|:||       .:|:|.|.|:  ::..
  Fly   561 --------------------------------STDPDEFQPG-------LVEIFKKCLE--KSSG 584

  Fly   829 KNVIDQSINSLLSSEKGLDLVVNAM-------------NIDTRATLQ-EFVATKHENLLRFFVTE 879
            ...||.|:.|.|.....|.::...:             |...:|.|. ...|..:|..:.|::..
  Fly   585 VRCIDGSVMSFLKFAPNLYILTVELIEDRFLRENELLKNCYAKAVLPLRAYARLYERFIDFYLLN 649

  Fly   880 INAVERVFTKLKKSPPMAKHQPAKISAIFWARLLGKKLKTSVLAFKRVEDE-----PA------- 932
            :|...:.:.:        .|:|:            .::|..:|..||:::|     ||
  Fly   650 VNTYMQAYAQ--------AHKPS------------SEVKRDILENKRLKEELREILPAFITIGPF 694

  Fly   933 -IKNSFLKRSSFKQYFELMTVMFQFEKVLFENFIQNATYLVNTTNRSNVLRIRICKESTMSYISE 996
             |....:|:...|:..|::..:|:              |.|:....:|.:.:..|.|..
  Fly   695 YINVDTMKQFMIKKRIEVVRRIFE--------------YYVDRMYETNEVLLDRCLEMF------ 739

  Fly   997 AVQTLKAKPRPELQMTSDRRVT--PVKSSNLMPVQSEAFSAYSVADSAGTEISSESENEGLLVGD 1059
                              ||:.  |:...:|          |.:.|.|.|            |.|
  Fly   740 ------------------RRIAERPISIEHL----------YEIRDFAQT------------VPD 764

  Fly  1060 TSQKKLMCRINRLTVLVAMIMWMVSNTRKANIQLQECTAFIKMVKDKKPKDVTAMDRHCVRTCEL 1124
            .        ::.|               ||:||:
  Fly   765 L--------VDEL---------------KADIQV------------------------------- 775

  Fly  1125 LQRAESQYLLPIWRELVGEKTLIEYDM--DFVVNLKRDVFDVLFEAQQFEHLGFTLPAVLRTAIM 1187
                       :|         :|||:  .|..||....|.:.:....:.|           .||
  Fly   776 -----------MW---------LEYDLLDSFFYNLSDHQFAMKWNVYAWPH-----------QIM 809

  Fly  1188 KKDLLFKDYERMTEVVDRYRSIINNLSMSEVIFLRGHIYDTELF------IQMGVGRYTWTSFNI 1246
            .:....|| |:..::.|               |||.|..:.:.|      :...|..|: .:||.
  Fly   810 VRLSTLKD-EQKVDIED---------------FLRLHASECQAFEERLESLNDEVQAYS-LAFNT 857

  Fly  1247 GKFCDQINSQLRKLTSIVSQINFIRLDLRSRIDMIKSFNLFNLDDELKVEDTSRSSGESYLQDRK 1311
            .: ..:.:..::|..:::.::..:...|:.|.:      ||.| :.|.||         :|:
  Fly   858 NR-AQETSVDIKKTWALIKELEKVSQTLQFRQE------LFEL-EPLSVE---------FLE--- 902

  Fly  1312 NPSQRFKSVTGETITMFSVEKDVPADEKAEQACGSGIYPCQGYFELLEASRNRKAAQ-------- 1368
                       ..|..|:..|::             .|.|..:.:|.:|:.....||
  Fly   903 -----------SIIASFTPYKNL-------------WYGCANFLKLEDATLGNPIAQLDLEDVWN 943

  Fly  1369 -MKKLYDSLGPVLVKLESLVLGTFSGRSDRMKTYYEYWEGETFKCIVDMTYQNLKCYINRLLSNK 1432
             :.:|.|.|                  ::.||.::|..|      |:|:.    |.:|.::....
  Fly   944 NLMRLRDEL------------------NESMKIFHEKVE------IMDVA----KTFIAKIDDFV 980

  Fly  1433 PMFEVNAVLLMSEIVLEPSVQELQNTIVTATKDYISRLRIFTRWMTGTCIACPLVEMGKQFKY-- 1495
            |::.              |:::::|      :::     ::..|...:.|.      |::.||
  Fly   981 PVYN--------------SIKDIRN------ENW-----MYIHWQELSAIT------GQEIKYSV 1014

  Fly  1496 --NYTYYEDVIQIRSIVDLVINIHDLASRVANEA 1527
              ||.|   :|: :.|:|::..:|.::.:..|||
  Fly  1015 AMNYQY---LIR-KGILDVLPEVHIISEKANNEA 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhc98D	NP_524541.3	DHC_N1	523..>968	CDD:462457	85/519 (16%)
		DHC_N2	1795..2196	CDD:462462
		DYN1	1999..4719	CDD:227570
		AAA_6	2338..2664	CDD:463697
		Dynein_C	4778..5076	CDD:465677
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	36/230 (16%)