DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1894 and kat7b

DIOPT Version :9

Sequence 1:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_997800.1	Gene:	kat7b / 323181	ZFINID:	ZDB-GENE-030131-1901	Length:	568	Species:	Danio rerio

Alignment Length:	421	Identity:	144/421 - (34%)
Similarity:	220/421 - (52%)	Gaps:	33/421 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NRSGDHLKYQPLGDQDGISSKLPDIPRALQLTNAKESSATRGLG----QSASKSEMGKSQLQNDS 65
            |.|.|..|.:      .|..:..|..|: |..|.:...|||...    |...|.::.:.:.:.||
Zfish   174 NLSADECKVK------AIEREKQDEERS-QGQNEENRHATRHQAPTPRQVRYKEKVIEMRKRRDS 231

  Fly    66 SLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTNASSNVDDRQRQETIDNEKSD 130
            .|.|: |:.|.:.    ..|..|.|.:..||             |.:|:.|....::.......|
Zfish   232 GLSKD-QKEKYME----HRQTHGTTREPLLE-------------NITSDYDLELFRKAQARASED 278

  Fly   131 VQKEKEDAKVKVIRN-IEKVQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSYHL 194
            ::|.:...::....| |:.:.|||||:||...||||....:...:||||||||||..:.....|:
Zfish   279 LEKLRLQGQITEGSNMIKTIFFGRYELETWYHSPYPEEYARLGRLYVCEFCLKYMKSQTILRRHM 343

  Fly   195 YDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCLKD 259
            ..|..:.|||..:|||....::||||.|.::|||.|||::||||::|.:.|....||||::...|
Zfish   344 AKCVWKHPPGDEVYRKGATSVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD 408

  Fly   260 KDGEHFAGYFAREK-TMLNINLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSKVA 323
            ..|.|..|||::|| :.||.|::|||.:|.|||:||||:|||.||.:|:.|..:|.|::|||.:.
Zfish   409 NTGCHLVGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLG 473

  Fly   324 RLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYTTS 388
            .:.|.|||..:||..:.:....: ::|:|:|:.|.....||:|||:.:.|.||:|..|::. ...
Zfish   474 LISYRSYWKEVLLRYMYNFKGKE-ISIKEISQETAVNPVDIVSTLQSLQMLKYWKGKHLVL-KRQ 536

  Fly   389 SIIEDRRGLAQFKKPRLTIHRNRLSWKTPTG 419
            .:|:|.:.....:....||....|.|..|.|
Zfish   537 DLIDDWKAKETKRGNSKTIDPGSLKWTPPKG 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	110/266 (41%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	79/176 (45%)
kat7b	NP_997800.1	zf-C2HC	144..170	CDD:279824
		NAT_SF	287..545	CDD:302625	108/259 (42%)
		MOZ_SAS	351..529	CDD:280097	80/178 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820