DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1894 and Tip60

DIOPT Version :9

Sequence 1:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001259234.1	Gene:	Tip60 / 31362	FlyBaseID:	FBgn0026080	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	123/318 - (38%)
Similarity:	183/318 - (57%)	Gaps:	10/318 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LLHTNASSNVDDRQRQETIDNEKSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDK 170
            |:...|:.:.|..|..:|....:|......:|..|..::|:|.::.||:.|:....||||....:
  Fly   220 LISGAANDDGDGSQDGKTPTPRQSGSMVTHQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQ 284

  Fly   171 ATTIYVCEFCLKYMCLRKSYSYHLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSK 235
            ...||:|||||||...||....||..|..|.|||:.:|||..|..:|:||.|.::|.|.|||::|
  Fly   285 MPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAK 349

  Fly   236 LFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREK-TMLNINLNCILVLPPYMRKGYGKLLI 299
            |||::|.:.|.:..||||::...|..|.|..|||::|| :..:.|:.|||.:|||.|||||||||
  Fly   350 LFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLI 414

  Fly   300 DLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNL-LRHHSSPD----LVTIEELSKATGF 359
            :.|||:|:.|...|.|:||||.:..|.|.|||...:|.: :..:.|.|    .:||.::.:.|..
  Fly   415 EFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSI 479

  Fly   360 REEDIISTLEFMGMTKYYKVDHIMFYTTSSIIEDRRGLAQFKKPRLTIHRNRLSWKTP 417
            ::||:||||:.:.:..|||..:|:......|.:.||.:   .|.::.|....|.| ||
  Fly   480 KKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAM---DKRKIRIDSKCLHW-TP 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	109/270 (40%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	79/181 (44%)
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553
		Drf_FH1	84..>157	CDD:283903
		PHA01732	139..>196	CDD:222828
		NAT_SF	254..533	CDD:302625	114/282 (40%)
		MOZ_SAS	316..500	CDD:280097	81/183 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10615
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850