DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1894 and Kat8

DIOPT Version :9

Sequence 1:NP_651620.1 Gene:CG1894 / 43378 FlyBaseID:FBgn0039585 Length:421 Species:Drosophila melanogaster
Sequence 2:NP_001017378.1 Gene:Kat8 / 310194 RGDID:1311512 Length:458 Species:Rattus norvegicus


Alignment Length:312 Identity:129/312 - (41%)
Similarity:190/312 - (60%) Gaps:16/312 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 QRQETIDNEKSDVQK------------EKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKA 171
            :.|:...:|.:.|||            |||...:..::.::|:..|.|||:....||:|....|.
  Rat   140 RNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQ 204

  Fly   172 TTIYVCEFCLKYMCLRKSYSYHLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKL 236
            ..:::||:|||||...|||.:||..|:.|.|||..:|||.||.:|||||...::|||.|||::||
  Rat   205 PKLWLCEYCLKYMKFEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKL 269

  Fly   237 FLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREKTMLN-INLNCILVLPPYMRKGYGKLLID 300
            ||::|.:.:....|:||||...|:.|.|..|||::||...: .|:.|||.||||.|:||||.||.
  Rat   270 FLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIA 334

  Fly   301 LSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDII 365
            .|||:|:.|:.:|.|:||||.:.:|.|.|||..:||.:||....  .::|::||:.|...:.|||
  Rat   335 FSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG--TLSIKDLSQMTSITQNDII 397

  Fly   366 STLEFMGMTKYYKVDHIMFYTTSSIIEDRRGLAQFKKPRLTIHRNRLSWKTP 417
            |||:.:.|.||:|..|:: ..|..::|:....||:|||.:|:....|.|..|
  Rat   398 STLQSLNMVKYWKGQHVI-CVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPP 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1894NP_651620.1 NAT_SF 130..395 CDD:302625 118/277 (43%)
MOZ_SAS 202..378 CDD:280097 85/176 (48%)
Kat8NP_001017378.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..52
PLN00104 21..449 CDD:215056 129/312 (41%)
Tudor-knot 55..111 CDD:288553
NAT_SF 160..427 CDD:302625 115/269 (43%)
Sufficient for interaction with KANSL1. /evidence=ECO:0000250|UniProtKB:Q9H7Z6 174..458 121/278 (44%)
Acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:Q9H7Z6 317..319 1/1 (100%)
Acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:Q9H7Z6 324..330 3/5 (60%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166338475
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5027
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG51854
OrthoDB 1 1.010 - - D629545at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10615
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
87.820

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