DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1894 and Kat7

DIOPT Version :9

Sequence 1:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_851595.1	Gene:	Kat7 / 303470	RGDID:	727966	Length:	612	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	141/423 - (33%)
Similarity:	219/423 - (51%)	Gaps:	34/423 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NRSGDHLKYQPLGDQDGISSKLPDIPRALQLTNAKESS---ATRGLG----QSASKSEMGKSQLQ 62
            |.|.|..|.:.......|..::        |::.::.:   |||...    |...|.::.:.:.:
  Rat   215 NLSADECKVRAQSRDKQIEERM--------LSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKK 271

  Fly    63 NDSSLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTNASSNVDDRQRQETIDNE 127
            .:|.|.|. |:.|.:.    ..|..|.|.:..||.:.....:.|...        .|.:.:.|.|
  Rat   272 RNSGLSKE-QKEKYME----HRQTYGNTREPLLENLTSEYDLDLFRR--------AQARASEDLE 323

  Fly   128 KSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSY 192
            |..:|.:..:..    ..|:.:.|||||::|...||||....:...:|:||||||||..:.....
  Rat   324 KLRLQGQITEGS----NMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRR 384

  Fly   193 HLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCL 257
            |:..|..:.|||..:|||.:|.::||||.|.::|||.|||::||||::|.:.|....||||::..
  Rat   385 HMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTE 449

  Fly   258 KDKDGEHFAGYFAREK-TMLNINLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSK 321
            .|..|.|..|||::|| :.||.|::|||.:|.|||:||||:|||.||.:|:.|..:|.|::|||.
  Rat   450 ADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSD 514

  Fly   322 VARLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYT 386
            :..:.|.|||..:||..| |:.....::|:|:|:.|.....||:|||:.:.|.||:|..|::...
  Rat   515 LGLISYRSYWKEVLLRYL-HNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKR 578

  Fly   387 TSSIIEDRRGLAQFKKPRLTIHRNRLSWKTPTG 419
            ...|.|.....|:......|:..:.|.|..|.|
  Rat   579 QDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKG 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	109/265 (41%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	82/176 (47%)
Kat7	NP_851595.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..174
		zf-C2HC	185..211	CDD:279824
		NAT_SF	330..608	CDD:302625	112/282 (40%)
		MOZ_SAS	394..572	CDD:280097	83/178 (47%)
		acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:O95251	476..478		1/1 (100%)
		acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:O95251	484..489		3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920