DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1894 and kat6a

DIOPT Version :9

Sequence 1:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001116784.4	Gene:	kat6a / 266966	ZFINID:	ZDB-GENE-021022-3	Length:	2246	Species:	Danio rerio

Alignment Length:	422	Identity:	144/422 - (34%)
Similarity:	217/422 - (51%)	Gaps:	55/422 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 SSATRGLGQSASKSEMGKSQ----LQNDSSLQKNIQETKTITGSCIEAQRIGATP-----KKQLE 96
            ||:......|:.:...|..:    |:.|.|...:::..|...| .|:|.....||     |.:.|
Zfish   392 SSSPHSSSSSSCEGYPGDDRMLFSLREDDSAHGSLRFNKKTKG-LIDALSKFFTPSPDGRKARAE 455

  Fly    97 GVKEPNMISLLHT-NASSNVDDRQRQETIDNEK-SDVQKEKED----------AKVKVIRNIEK- 148
            .|.......:... |.....|||    |.||:: ||..:|.||          ..|::.|:|::
Zfish   456 VVDYSQQYRMRKKGNRKGEHDDR----TGDNQECSDSWREDEDKLPGHENLTEKDVELFRHIQEI 516

  Fly   149 --------------------VQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSYH 193
                                ::||:|||:|..|||||....:...:|:|||||:||..|.....|
Zfish   517 ALQKVGVTGPPDPQMRCPSVIEFGKYEIQTWYSSPYPQEYSRLPKLYLCEFCLRYMKSRSILYQH 581

  Fly   194 LYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCLK 258
            :..|....||.:.:||||::.::||||:...:|||.|||::||||::|.:.|....||||:|...
Zfish   582 MRKCNWFHPPANEIYRKDDVSVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQN 646

  Fly   259 DKDGEHFAGYFAREK-TMLNINLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSKV 322
            |..|.|..|||::|| .....|::||::||.|.|||||:.|||.||.:|:||...|.|:||||.:
Zfish   647 DNKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQPGSPEKPLSDL 711

  Fly   323 ARLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYTT 387
            .||.|::||..::|..| |......::|.:|||.||...:||.:||..:.|.: .|.|.::....
Zfish   712 GRLSYMAYWRSVVLECL-HEIRDRQLSIRKLSKVTGICPQDITATLLNLNMLE-QKGDGVIIMRR 774

  Fly   388 SSIIEDRRGLAQFK-KPR-LTIHRNRLSWKTP 417
            ..::.:.  :|:.| ||| |.:..:.|.| ||
Zfish   775 EKLVANH--MARLKAKPRLLEVDPDCLRW-TP 803

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	110/296 (37%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	79/176 (45%)
kat6a	NP_001116784.4	H15	122..185	CDD:197772
		PHD1_MOZ_MORF	226..283	CDD:277090
		PHD2_KAT6A_6B	285..331	CDD:277002
		NAT_SF	535..804	CDD:302625	113/274 (41%)
		MOZ_SAS	590..767	CDD:280097	80/178 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820