DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1894 and Kat7

DIOPT Version :9

Sequence 1:	NP_651620.1	Gene:	CG1894 / 43378	FlyBaseID:	FBgn0039585	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_006533076.1	Gene:	Kat7 / 217127	MGIID:	2182799	Length:	613	Species:	Mus musculus

Alignment Length:	423	Identity:	141/423 - (33%)
Similarity:	219/423 - (51%)	Gaps:	34/423 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NRSGDHLKYQPLGDQDGISSKLPDIPRALQLTNAKESS---ATRGLG----QSASKSEMGKSQLQ 62
            |.|.|..|.:.......|..::        |::.::.:   |||...    |...|.::.:.:.:
Mouse   216 NLSADECKVRAQSRDKQIEERM--------LSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKK 272

  Fly    63 NDSSLQKNIQETKTITGSCIEAQRIGATPKKQLEGVKEPNMISLLHTNASSNVDDRQRQETIDNE 127
            .:|.|.|. |:.|.:.    ..|..|.|.:..||.:.....:.|...        .|.:.:.|.|
Mouse   273 RNSGLSKE-QKEKYME----HRQTYGNTREPLLENLTSEYDLDLFRR--------AQARASEDLE 324

  Fly   128 KSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKATTIYVCEFCLKYMCLRKSYSY 192
            |..:|.:..:..    ..|:.:.|||||::|...||||....:...:|:||||||||..:.....
Mouse   325 KLRLQGQITEGS----NMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRR 385

  Fly   193 HLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSKLFLENKKILYSSSSFLFYILCL 257
            |:..|..:.|||..:|||.:|.::||||.|.::|||.|||::||||::|.:.|....||||::..
Mouse   386 HMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTE 450

  Fly   258 KDKDGEHFAGYFAREK-TMLNINLNCILVLPPYMRKGYGKLLIDLSYEISRREACIGGPKKPLSK 321
            .|..|.|..|||::|| :.||.|::|||.:|.|||:||||:|||.||.:|:.|..:|.|::|||.
Mouse   451 ADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSD 515

  Fly   322 VARLCYLSYWGHILLNLLRHHSSPDLVTIEELSKATGFREEDIISTLEFMGMTKYYKVDHIMFYT 386
            :..:.|.|||..:||..| |:.....::|:|:|:.|.....||:|||:.:.|.||:|..|::...
Mouse   516 LGLISYRSYWKEVLLRYL-HNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKR 579

  Fly   387 TSSIIEDRRGLAQFKKPRLTIHRNRLSWKTPTG 419
            ...|.|.....|:......|:..:.|.|..|.|
Mouse   580 QDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKG 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1894	NP_651620.1	NAT_SF	130..395	CDD:302625	109/265 (41%)
CG1894	NP_651620.1	MOZ_SAS	202..378	CDD:280097	82/176 (47%)
Kat7	XP_006533076.1	Herpes_BLLF1	<29..>199	CDD:282904
		zf-C2HC	186..214	CDD:366692
		PLN00104	<326..611	CDD:215056	113/289 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820