DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-VI and cd276

DIOPT Version :9

Sequence 1:	NP_001263035.1	Gene:	beat-VI / 43377	FlyBaseID:	FBgn0039584	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001074091.2	Gene:	cd276 / 791140	ZFINID:	ZDB-GENE-070112-452	Length:	300	Species:	Danio rerio

Alignment Length:	256	Identity:	54/256 - (21%)
Similarity:	95/256 - (37%)	Gaps:	73/256 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 MLALSWIIISELLLSAHCLKDLKIFVPEA---VLMGNAATLSCQ------YDLEQAALYAVRW-- 87
            ||||  ::.|.|:|.:|.| |::  |||:   ||.|:.|.|:|.      ::|...:::   |
Zfish     1 MLAL--LLFSLLVLQSHAL-DVR--VPESPVVVLFGSDALLNCSFSGVSAFNLSDVSVF---WQL 57

  Fly    88 ----------YFGQEEFYRYVPREAKPTFVFAVAGINVDLANSDATSVTLKGVTRELSGSYQCEV 142
                      :..|::......|.:..|.:|:      |.......|:.::.|.....|:|.|.|
Zfish    58 SDTKRSVHSFWKSQDQLTDQDERFSGRTTLFS------DQLMVGNASLRIRKVRVADEGTYSCFV 116

  Fly   143 SEDAPLFHTEIRS----AHMQVIELPKDDPVMQVDK-KVIGVNDNFKAVCTVGPSYPPANITWSI 202
                     .::|    |.:..:..|...|::..|. ..:...|.....|.....:|.|.:.|.
Zfish   117 ---------RVQSYGSAAVIMQVAAPFSKPLVSWDSDSSLKPGDAVSLSCVAYGGFPQAQLQWQ- 171

  Fly   203 NGNQIRRTPLQRISQDTYEGSTTYSSLDIYPNSQALQGFFETKYQHSVNLQ------CVVT 257
            :|:....|....:||...|                 :|.|..:...||:|:      |.:|
Zfish   172 DGSGHNLTENITVSQLANE-----------------EGLFSVRSVLSVHLEPNSTYSCRIT 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-VI	NP_001263035.1	Ig	66..142	CDD:416386	16/93 (17%)
		Ig strand B	67..76	CDD:409353	3/14 (21%)
		CDR1	76..83	CDD:409353	1/6 (17%)
		Ig strand C	83..91	CDD:409353	1/19 (5%)
		FR2	84..91	CDD:409353	1/18 (6%)
		CDR2	94..108	CDD:409353	2/13 (15%)
		Ig strand C'	94..99	CDD:409353	0/4 (0%)
		Ig strand C'	102..104	CDD:409353	0/1 (0%)
		FR3	109..143	CDD:409353	6/33 (18%)
		Ig strand D	117..121	CDD:409353	0/3 (0%)
		Ig strand E	123..127	CDD:409353	1/3 (33%)
		Ig strand F	136..144	CDD:409353	4/7 (57%)
cd276	NP_001074091.2	Ig	36..117	CDD:325142	15/98 (15%)
cd276	NP_001074091.2	Ig	97..219	CDD:325142	28/146 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000