DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and CWC27

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_015261.1	Gene:	CWC27 / 856041	SGDID:	S000005985	Length:	301	Species:	Saccharomyces cerevisiae

Alignment Length:	330	Identity:	75/330 - (22%)
Similarity:	125/330 - (37%)	Gaps:	88/330 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GRIVFELFNDVAPKTAENFRALCTGEKGFGLITG---KKLQ-YKGVIFHRVVKDFMVQAGDFSAG 87
            |.|..||:....|:|.:.|.::.:.    |..|.   |:|: .:.::|:               .
Yeast    20 GNIAIELWAKECPETCKRFLSMLSD----GTFTNGEFKELKPTQWLMFN---------------A 65

  Fly    88 NGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITT-QPAPHLDNIHVVFGQVIS 151
            |.||.   |....|:::...:.:|..||.. :|.:||    :|||. ..:.|:.|...|||:::
Yeast    66 NSTGE---YRTVAEEKNPRIRFNRDGLLGW-DRRRNT----WFITVLADSKHVLNDCNVFGKIV- 121

  Fly   152 GQE--LVRQLEGLPVDRNSRP-----------LQDAAIA--------------NCGELVRQTKAK 189
            |:.  :.|::.|..::.:||.           |:|..|.              ...|...|..||
Yeast   122 GKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAK 186

  Fly   190 KEKKHKRRSTATEDSNSEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDD 254
            |..|..:.....||    |.|.:...|:|.|.:||.......:.|      ||..|.......|.
Yeast   187 KLVKSAKVKMVYED----EQEDDDGDVQKLKPRKRMILPAWIKDD------SRSEGIKLDASLDQ 241

  Fly   255 DED---REEGELHPLVTITKIDPNEIPEVSNKFLMRAERSKS--LDREERGARGQDRDRGKDQDR 314
            .::   ||:.|||          :.:.|.:.|.....|..|.  :|:.||.....   ..|.|:|
Yeast   242 PQEALIREKTELH----------DNVDEATTKETESQENIKEEPMDKRERETLAM---LSKFQER 293

  Fly   315 DRSRN 319
            .:::|
Yeast   294 IKNKN 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	39/184 (21%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
CWC27	NP_015261.1	cyclophilin	6..167	CDD:412213	39/174 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900