DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and CPR5

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_010590.3	Gene:	CPR5 / 851898	SGDID:	S000002712	Length:	225	Species:	Saccharomyces cerevisiae

Alignment Length:	198	Identity:	87/198 - (43%)
Similarity:	120/198 - (60%)	Gaps:	12/198 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFM 78
            :.:|||:.|...:||||..|:....|:|.|||..|.       :....|:.|...|||||:.:||
Yeast    35 KVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLT-------ISRDPKMGYLNSIFHRVIPNFM 92

  Fly    79 VQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIH 143
            :|.|||:..:|.||:||:|.||:||:|:.|||:|..|||||||||||||||||||.|.|.||..|
Yeast    93 IQGGDFTHRSGIGGKSIFGNTFKDENFDVKHDKPGRLSMANRGKNTNGSQFFITTVPCPWLDGKH 157

  Fly   144 VVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSNSEE 208
            ||||:|:.|.::|..:|.:..|..:.|:::..|...|||.......|:     .:...|:..:|.
Yeast   158 VVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVESGELETVPLDNKD-----AAKLQEEIKAEA 217

  Fly   209 SEA 211
            |||
Yeast   218 SEA 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	78/165 (47%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
CPR5	NP_010590.3	cyclophilin	34..194	CDD:412213	78/165 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810