DRSC/TRiP Functional Genomics Resources

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Protein Alignment Moca-cyp and Ppil2

DIOPT Version :9

Sequence 1:NP_733246.1 Gene:Moca-cyp / 43374 FlyBaseID:FBgn0039581 Length:970 Species:Drosophila melanogaster
Sequence 2:XP_006522510.1 Gene:Ppil2 / 66053 MGIID:2447857 Length:564 Species:Mus musculus


Alignment Length:361 Identity:105/361 - (29%)
Similarity:147/361 - (40%) Gaps:112/361 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 GRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTG 91
            |.:..||..|:.|||.|||..||           ||..|.|.||||.:::|::|.|| ..|.|||
Mouse   289 GDLNLELHCDLTPKTCENFIKLC-----------KKQYYDGTIFHRSIRNFVIQGGD-PTGTGTG 341

  Fly    92 GESIYGGTFEDESFEK--KHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQE 154
            |||.:|..|:|| |..  .|....:|||||.|.|||.||||||.:...:||..|.:||:|:.|.:
Mouse   342 GESFWGKPFKDE-FRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAYLDKKHTIFGRVVGGFD 405

  Fly   155 LVRQLEGLPVD-RNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSNSEESEAEAKVVRK 218
            .:..:|.:..| :..||.::..|.                     |.|...:..| ||:|::.::
Mouse   406 TLTAMENVESDPKTDRPKEEVLIC---------------------TTTVFVDPYE-EADAQIAQE 448

  Fly   219 AKKKKR------SRKDTKSQSDSEDNETSR-GNGKHDQTPQDDDEDREEGELHPLVTITKIDPNE 276
            .||.:.      ..|.::.|..::..:|.| |.||:               :||..||       
Mouse   449 RKKTQHQVDPEAKVKMSQPQPGNQGPQTYRQGVGKY---------------IHPAATI------- 491

  Fly   277 IPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSR----------NNFGWSKKQAPPT 331
                   ||                    ...|.||.|...|          ...|.....||.:
Mouse   492 -------FL--------------------HVSGNDQQRKNHRPALPPPRPRKGPVGALGTSAPGS 529

  Fly   332 SR--SG-----RIVKGRGVFRFRTPSRSRSRSTTPP 360
            ||  ||     ::::| ||...|||....|:....|
Mouse   530 SRLASGILATHKLLQG-GVRSIRTPEALGSQRALRP 564

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Moca-cypNP_733246.1 cyclophilin 13..180 CDD:294131 64/155 (41%)
SH3-RhoG_link 635..>718 CDD:293215
Ppil2XP_006522510.1 RING-Ubox_PPIL2 38..110 CDD:319577
RING_Ubox 100..159 CDD:388418
U-box domain, a modified RING finger 103..146 CDD:319361
cyclophilin_RING 281..440 CDD:238904 67/185 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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