Protein Alignment Moca-cyp and ppil4

DIOPT Version :10

• Sequence 1: NP_733246.1
• Gene: Moca-cyp / 43374
• FlyBaseID: FBgn0039581
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_001121802.1
• Gene: ppil4 / 554886
• ZFINID: ZDB-GENE-030131-6251
• Length: 454
• Species: Danio rerio
• Alignment Length: 590
• Identity: 146/590 - (24%)
• Similarity: 219/590 - (37%)
• Gaps: 170/590 - (28%)

  Fly    26 MGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGT 90
            :|.||.:|:.:..||.:.||..||           |...|...:.|.|.:||::|.|| ..|.|.
Zfish     9 LGDIVIDLYTEERPKASLNFLKLC-----------KIKYYNYCLIHNVQRDFIIQTGD-PTGTGR 61

  Fly    91 GGESI----YGGT---FEDESFEK-KHDRPFLLSMANRGKNTNGSQFFITT-QPAPHLDNIHVVF 146
            ||||:    ||..   ||.|...: ||.:...:||.|.|.:.:||||.||| :...:||.:|.||
Zfish    62 GGESVFCKLYGDQARFFESEKMPRIKHRKKGTVSMVNNGSDQHGSQFLITTGENVDYLDGVHTVF 126

  Fly   147 GQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSNSEESEA 211
            |:|..|.:::.::....||.:..|.||..|                   ..:...:|...:.:..
Zfish   127 GEVTEGMDVLAKINETFVDNDFIPFQDIRI-------------------NHTVILDDPFDDPAGL 172

  Fly   212 EAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGELHPLVTITKIDPNE 276
            ..        ..||.:.||.|.||       |....|:...||     ||:          ||.|
Zfish   173 PV--------PDRSPEPTKQQLDS-------GRIGADEAINDD-----EGK----------DPEE 207

  Fly   277 IPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRD-RSRNNFGWSKKQAPPT--------- 331
            :.|:..            |:|.:.........|...|.| :...|..:..|..|.|
Zfish   208 LDELIK------------DKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIF 260

  Fly   332 SRSGRIVKGRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLSDLERIEEESKMREEEMKRREHER 396
            ||.| ::|...:.|               .||..:.......:.|: ||:.:....:|.....:.
Zfish   261 SRFG-LIKCCEIIR---------------DWKTGESLCYAFIEFEK-EEDCEKAYFKMDNVLIDD 308

  Fly   397 KRRHEEATKNPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTADRGKAKEREKAGEKDKARDV 461
            :|.|.:.:    ||..::..... |||.|.|.|    ||..||..::.|...::|...|..:|
Zfish   309 RRIHVDFS----QSVSKIKWKGK-GGKYTKDDF----KAYEKDLDNKAKLALKDKVKSKQDSR-- 362

  Fly   462 TPVKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSKQDIRVEPSTSKDRNAKRDERKPTE-E 525
                           ||...:   |.||:.:                  ||...||:.::.:: |
Zfish   363 ---------------YELLLD---EDEDDGR------------------KDDREKRERKRHSDSE 391

  Fly   526 KAKPKRSRSRSPRRQSPARRQQRSPARRPGQNYNQNQNQNQNQNQNQNQLNRGNRRNPFADRDRR 590
            :.|.|||:.|...|:...|.:|||.:|             ..:.|...|..||..|:....|.||
Zfish   392 RTKDKRSKDRDESRREKDRSRQRSRSR-------------DRERQKDKQRERGRDRDGDHKRHRR 443

  Fly   591 RRSRS 595
            .||||
Zfish   444 ERSRS 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:469651	57/162 (35%)
		PRK12678	612..>804	CDD:237171
ppil4	NP_001121802.1	cyclophilin_RRM	4..169	CDD:238902	58/190 (31%)
		RRM_PPIL4	237..319	CDD:409681	18/102 (18%)
		SF-CC1	375..>454	CDD:273721	28/105 (27%)