DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and ppie

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_001017678.1	Gene:	ppie / 550373	ZFINID:	ZDB-GENE-050417-167	Length:	302	Species:	Danio rerio

Alignment Length:	175	Identity:	88/175 - (50%)
Similarity:	108/175 - (61%)	Gaps:	9/175 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRV 73
            |.|.|:.:.||.:|....||:.|.|..||.|.||||||.|||.|||||        :||..|||:
Zfish   137 GRTNPQVYMDIKIGNKPAGRLRFLLRADVVPMTAENFRCLCTHEKGFG--------FKGSSFHRI 193

  Fly    74 VKDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPH 138
            :..||.|.|||:..|||||:||||..||||:|..||.....|||||.|.||||||||||......
Zfish   194 IPQFMCQGGDFTNHNGTGGKSIYGRKFEDENFVLKHTHAGQLSMANSGPNTNGSQFFITVDKTDW 258

  Fly   139 LDNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELV 183
            ||..|||||::..|.:::|.:|.... ::.:|.|...|:||||.|
Zfish   259 LDGKHVVFGELTEGMDVLRAMEAQGT-KDGKPKQKVIISNCGEYV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	82/166 (49%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
ppie	NP_001017678.1	RRM_PPIE	8..80	CDD:240793
ppie	NP_001017678.1	cyclophilin_ABH_like	141..299	CDD:238907	82/166 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910