DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and PPIL3

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_115861.1	Gene:	PPIL3 / 53938	HGNCID:	9262	Length:	165	Species:	Homo sapiens

Alignment Length:	158	Identity:	62/158 - (39%)
Similarity:	81/158 - (51%)	Gaps:	20/158 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 MGRIVFELFNDVAPKTAENFRALCTGEKG-----FGLITGKKLQYKGVIFHRVVKDFMVQAGDFS 85
            :|.|..|:|.:..|||.| ..:.|..:.|     .|.:......:|.|....:.:
Human     9 VGDIKIEVFCERTPKTCE-MESRCVPQAGVQWRDLGSLQPPPPGFKQVFCLSLPR---------- 62

  Fly    86 AGNGTGGESIYGGTFEDESFE-KKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQV 149
              .|.||.||:|..||||..| .||:...::||||.|.||||||||||....||||..:.|||:|
Human    63 --TGRGGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKV 125

  Fly   150 ISGQELVRQLEGLPV-DRNSRPLQDAAI 176
            |.|.|.:.:||.||| ::..|||.|..|
Human   126 IDGLETLDELEKLPVNEKTYRPLNDVHI 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	62/158 (39%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
PPIL3	NP_115861.1	cyclophilin	1..158	CDD:294131	62/158 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810