DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and ppifa

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_001004626.1	Gene:	ppifa / 447887	ZFINID:	ZDB-GENE-040912-52	Length:	189	Species:	Danio rerio

Alignment Length:	172	Identity:	92/172 - (53%)
Similarity:	109/172 - (63%)	Gaps:	13/172 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDF 77
            |..|.||:..|..:|||:.|||.||.|||..|||||||||.|||        |||.:|||::.:|
Zfish    28 PVVFMDIAADGEFIGRIIIELFADVVPKTVANFRALCTGEHGFG--------YKGSVFHRIIPEF 84

  Fly    78 MVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNI 142
            |.|.|||:..|||||:||||..|.||:|:.||....:|||||.|.|||||||||.|.....||..
Zfish    85 MCQGGDFTNHNGTGGKSIYGKKFNDENFKLKHTGAGILSMANSGPNTNGSQFFICTAKTEWLDGK 149

  Fly   143 HVVFGQVISGQELVRQLE--GLPVDRNSRPLQDAAIANCGEL 182
            |||||||..|.|.|..:|  ||   .:...::..||.:||||
Zfish   150 HVVFGQVKEGMETVSLMESYGL---HDGGTVKKVAITDCGEL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	88/168 (52%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
ppifa	NP_001004626.1	cyclophilin_ABH_like	28..186	CDD:238907	88/168 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750