Protein Alignment Moca-cyp and ppig

DIOPT Version :9

• Sequence 1: NP_733246.1
• Gene: Moca-cyp / 43374
• FlyBaseID: FBgn0039581
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_998629.1
• Gene: ppig / 406773
• ZFINID: ZDB-GENE-040426-2822
• Length: 687
• Species: Danio rerio
• Alignment Length: 850
• Identity: 293/850 - (34%)
• Similarity: 435/850 - (51%)
• Gaps: 198/850 - (23%)

  Fly    10 ATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVV 74
            |.||||||||.:..:..||:|.|||:||.|||.||||.|||||||.|..|.|.|.|||..|||:|
Zfish     5 AQRPRCFFDIGISNVPAGRVVIELFSDVCPKTCENFRCLCTGEKGVGKTTQKPLHYKGTPFHRIV 69

  Fly    75 KDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHL 139
            ||||:|.||||.|||.||||||||.|||.||..||.:.||||||||||:||||||||||:|.|||
Zfish    70 KDFMIQGGDFSEGNGRGGESIYGGFFEDGSFSMKHTKEFLLSMANRGKDTNGSQFFITTKPTPHL 134

  Fly   140 DNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATED- 203
            |.|||||||||:||:::|.:|....|.||||..:..:.||||||.::|||||||..:.|:.:||
Zfish   135 DGIHVVFGQVITGQDVIRMIESQKTDTNSRPYAEVKVLNCGELVPKSKAKKEKKKHQSSSESEDS 199

  Fly   204 -----SNSEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGEL 263
                 |:|||||.|.|..:|.||:.:.:|::|.:     .:..:|:.:.:..||
Zfish   200 SSDSSSDSEESEKEKKRRKKHKKEHKKKKESKHK-----KKEKKGSDEEEAEPQ----------- 248

  Fly   264 HPLVTITKIDPNEIPEV-SNKFLMR--------AERSKSLDREERG-ARGQDRDRGKDQDRDRSR 318
                .::.|.|.|:|.: .|:||||        .|:||..|:.:.| .|.:||||.::::|:|..
Zfish   249 ----AVSTIRPEEVPPIPENRFLMRRSPEKPKEEEQSKEKDKVDSGRERPRDRDRERERERERPM 309

  Fly   319 NNFGWSKKQAPPTSRSGRIVKGRGVFRFRTPSRSRS-------RSTTPPHWKHAQKRTIKLSDLE 376
            .|...::.:...| ||||.:||||..|:||||||||       ||.|||||:|..:||.|
Zfish   310 ANSRPNRTRLVMT-RSGRRIKGRGPRRYRTPSRSRSRSWDRFRRSETPPHWRHEMQRTQK----- 368

  Fly   377 RIEEESKMREEEMKRREHERKRRHEEATKNPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTA 441
               .::.:...:.:..:.::....||.||..     |||..:             :.:...:|||
Zfish   369 ---AKANLAASQERWIKGDKGDMSEEKTKTT-----ELSSVN-------------KARGDKQDTA 412

  Fly   442 DRGKAKEREKAGEKDKARDVTPVKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSK-QDIRV 505
             |..:::.:|..::||:|.                                     ||| :|.:.
Zfish   413 -RKNSEQEKKVSKRDKSRS-------------------------------------PSKGRDRKR 439

  Fly   506 EPSTSKDRNAKRDERKPTEEKAKPKRSRSRSPRRQSPARRQQRSPARRPGQNYNQNQNQNQNQNQ 570
            :...||.|  :||.||..:..|:.|:|||||   :|..:::::..:::|.
Zfish   440 DKHRSKSR--ERDARKKPDADAEKKKSRSRS---KSKDKKREKEKSKKPD--------------- 484

  Fly   571 NQNQLNRGNRRNPFADRDRRRRSRSQDNEYRNRYPLSPIRGRGSPSGDRRRQQRSRSQNRRQDSP 635
                             |:|.||.|::.:.:.:             .|:..:|:.||:.|.:|..
Zfish   485 -----------------DKRGRSASKEKDRKEK-------------NDKEVEQKDRSKERAKDGE 519

  Fly   636 SQRRQLSPGRK---RQDSPSKKRPNSTERKWRDSPERKRDDSHDRKREASPNWKRDDSPARKRKD 697
            .::.:....:|   |:.|.||::.....|:.|.....:|..|.||.|:              |:.
Zfish   520 KEKSKEVEKKKNGERERSRSKEKGRDVSRRSRSRGRGQRGQSRDRGRD--------------RRH 570

  Fly   698 SANRKREDSQDKKIQDSKRQEDSAGKKREDSPSKKRKDSDKKRQDSPVKRQESPGRKRQDSPERK 762
            |::|:|:.|     ..|:.:|.:.|:..||    :||.:|.       |.:|:.||.| .|.||.
Zfish   571 SSSRERKTS-----HRSRSRERARGRDAED----RRKSADN-------KSRETRGRDR-SSKERS 618

  Fly   763 RRDSPDRRRKDSPARRRQES-SGRRRQDSDGRRRRESSGNRRSRSRGRWHSSSRSRSPSTSRSRR 826
            .:....|.|:|...||:.:| :|....|:|.|::|::|.:.:|:.|.:    .:|:||.....::
Zfish   619 SQKQRSREREDRQKRRKDKSDTGSSDSDNDKRKKRKTSDSPKSKERAK----DKSKSPRKDAKKK 679

  Fly   827 RRSRS 831
            ..|.|
Zfish   680 DSSSS 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	111/166 (67%)
		SH3-RhoG_link	635..>718	CDD:293215	18/85 (21%)
ppig	NP_998629.1	cyclophilin	8..175	CDD:294131	111/166 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2303
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	432	1.000	Inparanoid score	I1677
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		oto39366
orthoMCL	1	0.900	-	-		OOG6_105724
Panther	1	1.100	-	-	LDO	PTHR11071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8699
SonicParanoid	1	1.000	-	-		X5641
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.860