Protein Alignment Moca-cyp and cwc27

DIOPT Version :9

• Sequence 1: NP_733246.1
• Gene: Moca-cyp / 43374
• FlyBaseID: FBgn0039581
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_957397.1
• Gene: cwc27 / 394078
• ZFINID: ZDB-GENE-040426-1118
• Length: 470
• Species: Danio rerio
• Alignment Length: 565
• Identity: 146/565 - (25%)
• Similarity: 232/565 - (41%)
• Gaps: 162/565 - (28%)

  Fly    27 GRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTG 91
            |.|..||::...||...||..||.  :|:         |.|.||||:|.:|:||.|| ..|.|||
Zfish    22 GDIDIELWSKETPKACRNFVQLCM--EGY---------YDGTIFHRMVPEFIVQGGD-PTGTGTG 74

  Fly    92 GESIYGGTFEDESFEK-KHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQEL 155
            ||||||..|:||...: :.:|..|::|||.|.:.||||||.|...|..|:|.|.:||:| :|..:
Zfish    75 GESIYGRPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKV-TGDTV 138

  Fly   156 --VRQLEGLPVDRNSRPLQDAAIANCGEL--------VRQTKAKKEKK----HKRRSTATED--- 203
              :.:|..:..|.:.|||....|.:...|        .|:.|.||||.    .|.:|.||::
Zfish   139 YNMLRLADVACDGDERPLNPHKIRSTEVLHSPFDDIIPREIKGKKEKNKDEAKKSQSKATKNFSL 203

  Fly   204 -SNSEESEAEAKVVRKAKKKKRSRKDTKSQSD--SEDNETS------RGNGKHDQTPQDDDEDRE 259
             |..||:|.:.::|.:..:..:.:  :||..|  .:|.:.|      |..|:.|....|||||..
Zfish   204 LSFGEEAEEDEEMVNQVSQTMKGK--SKSSHDLLKDDPKLSSVPVVDRNQGEGDFEDSDDDEDDA 266

  Fly   260 EGELHPLVTITKIDPNEIPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSRNNFGWS 324
            |.:                  |::   .||::|.   .|..|:...:|:   .|.::|      |
Zfish   267 EDD------------------SDR---EAEKAKV---RENIAKKLKKDK---TDEEKS------S 298

  Fly   325 KKQAPPTSRSGRIVKGRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLSDLERIEEESKMREEEM 389
            :.....||||                                         :.:.:|::..::|:
Zfish   299 QDLVKKTSRS-----------------------------------------DELRKEARQLKKEL 322

  Fly   390 ---KRREHERKRRHEEATK--NPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTADRGKAKER 449
               |:|:.:..::.|:.::  :.||:    |.|.|            |:....|...|..|.|.:
Zfish   323 LAIKQRKEDGVKKEEDVSEVGDSKQN----SEAVT------------EYLESRKKYDDMRKQKLK 371

  Fly   450 EKAGEK--------------DKARDVTPVKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSK 500
            :.:|.:              ..|...||....:.::..|.|.::...:.|...||:..|||..:.
Zfish   372 KGSGREAQTLALLESFKSKLSSAISETPSAPEEDVEELAEDDDKGWMAHVLHFDEQSRKVKDANM 436

  Fly   501 QDIRVEPSTSKDRNAKRDERKPTEEKAKPKRSRSRSPRRQSPARR 545
            ||        :|.....|.|.|..   |.:|..|:...:...|||
Zfish   437 QD--------EDTFEIYDPRNPVN---KRRREESKKLLKDKKARR 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	63/155 (41%)
		SH3-RhoG_link	635..>718	CDD:293215
cwc27	NP_957397.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	64/168 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..377		59/296 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	428..470		13/52 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900