DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and ppil2

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_957285.2	Gene:	ppil2 / 393966	ZFINID:	ZDB-GENE-040426-1096	Length:	524	Species:	Danio rerio

Alignment Length:	235	Identity:	83/235 - (35%)
Similarity:	116/235 - (49%)	Gaps:	28/235 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTG 91
            |.:..||..|..||..|||..||  :||:         |.|.:|||.:::||:|.|| ..|.|||
Zfish   289 GDLNVELHCDKVPKAGENFIKLC--KKGY---------YDGTVFHRSIRNFMIQGGD-PTGTGTG 341

  Fly    92 GESIYGGTFEDESFEK--KHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQE 154
            |||.:|..|:|| |..  .|....:|||||.|.|||.||||||.:...:||..|.|||:|:.|.|
Zfish   342 GESFWGKPFKDE-FRPNLSHTGRGILSMANSGPNTNKSQFFITFRSCAYLDRKHSVFGRVVGGLE 405

  Fly   155 LVRQLEGLPVD-RNSRPLQDAAIANCGELV-------RQTKAKKEKK----HKRRSTATEDSNSE 207
            .:..:|.:..| :..:|..:..|.:....|       .|..|::||:    .:.|:..:...|..
Zfish   406 TLSAMENVESDPKTDKPKSEIKILSTSVFVDPYEEADAQIAAEREKEAQKVEEERAQTSALVNKA 470

  Fly   208 ESEAEAKVVRKAKKKKRSRKDTK-SQSDSEDNETSRGNGK 246
            ::|.:.|..|....|..:...|| |..|:|...||....|
Zfish   471 KTEEKPKAFRPGVGKYINMSATKHSHPDAEKPSTSEAPAK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	64/155 (41%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
ppil2	NP_957285.2	Ubox	42..96	CDD:128780
ppil2	NP_957285.2	cyclophilin_RING	281..440	CDD:238904	65/163 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900