DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and ppiaa

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_997923.1	Gene:	ppiaa / 336612	ZFINID:	ZDB-GENE-030131-8556	Length:	164	Species:	Danio rerio

Alignment Length:	171	Identity:	88/171 - (51%)
Similarity:	111/171 - (64%)	Gaps:	9/171 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKD 76
            ||:.|||::.||..:||:|.||..||.|:||||||.||||:.|:|        |||..||||:..
Zfish     3 RPKVFFDLTAGGNPVGRVVMELRADVVPRTAENFRQLCTGQPGYG--------YKGSSFHRVIPG 59

  Fly    77 FMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDN 141
            ||.|.|||:..|||||:||||..|.||:|..||.....|||||.|.|||||||||.|.....||.
Zfish    60 FMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDG 124

  Fly   142 IHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGEL 182
            .|||||||:.|.::::::||.. ..:.:......||:||:|
Zfish   125 KHVVFGQVVEGLDVIKKVEGFG-SSSGKTSAKIIIADCGQL 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	84/166 (51%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
ppiaa	NP_997923.1	cyclophilin_ABH_like	4..162	CDD:238907	84/166 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750