DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and Ppil1

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_001029360.1	Gene:	Ppil1 / 309651	RGDID:	1309119	Length:	166	Species:	Rattus norvegicus

Alignment Length:	165	Identity:	67/165 - (40%)
Similarity:	89/165 - (53%)	Gaps:	18/165 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDF 77
            |..:.:.|     ||.||.||:...||||.:||..|  ..:|:         |.|..|||::|||
  Rat    12 PNVYLETS-----MGIIVLELYWKHAPKTCKNFAEL--ARRGY---------YNGTKFHRIIKDF 60

  Fly    78 MVQAGDFSAGNGTGGESIYGGTFEDESF-EKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDN 141
            |:|.|| ..|.|.||.||||..||||.. :.|.....:|:|||.|.:|||||||:|..|...||.
  Rat    61 MIQGGD-PTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDG 124

  Fly   142 IHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAI 176
            .|.:||:|..|..:|.::..:..:...||:.|..|
  Rat   125 KHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKI 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	67/165 (41%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
Ppil1	NP_001029360.1	cyclophilin_SpCYP2_like	15..161	CDD:238903	66/162 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000