DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Moca-cyp and Ppie

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_001382655.1	Gene:	Ppie / 298508	RGDID:	1311411	Length:	301	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	86/171 - (50%)
Similarity:	109/171 - (63%)	Gaps:	9/171 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVK 75
            :.|:.:.||.:|....|||...|.:||.|.||||||.|||.|||||        :||..|||::.
  Rat   138 SNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFG--------FKGSSFHRIIP 194

  Fly    76 DFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLD 140
            .||.|.|||:..|||||:||||..|:||:|..||..|.||||||.|.||||||||:|......||
  Rat   195 QFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLD 259

  Fly   141 NIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGE 181
            ..|||||::..|.:::||:|. ...::.:|.|...||:|||
  Rat   260 GKHVVFGEITDGLDVLRQIEA-QGSKDGKPKQKVIIADCGE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	83/166 (50%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
Ppie	NP_001382655.1	RRM_PPIE	8..82	CDD:409783
Ppie	NP_001382655.1	cyclophilin_ABH_like	140..298	CDD:238907	83/166 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810