Protein Alignment Moca-cyp and Ppig

DIOPT Version :9

• Sequence 1: NP_733246.1
• Gene: Moca-cyp / 43374
• FlyBaseID: FBgn0039581
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_001074555.1
• Gene: Ppig / 228005
• MGIID: 2445173
• Length: 752
• Species: Mus musculus
• Alignment Length: 870
• Identity: 298/870 - (34%)
• Similarity: 433/870 - (49%)
• Gaps: 182/870 - (20%)

  Fly    12 RPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKD 76
            ||||||||::.....||:|||||:||.|||.||||.|||||||.|..|.|.|.||..:|||||||
Mouse     7 RPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKD 71

  Fly    77 FMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDN 141
            ||||.||||.|||.||||||||.||||||..||::.||||||||||:||||||||||:|.||||.
Mouse    72 FMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDG 136

  Fly   142 IHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRS-------- 198
            .||||||||||||:||::|....|..|:|..:..|.:||||:.::|.|||:|.:.:|
Mouse   137 HHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSD 201

  Fly   199 --------TATEDSNSEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDD 255
                    :::|.|:||.:..|....||.|.:|.|||..|.:...:         |..::|..:.
Mouse   202 SDSSSDSQSSSESSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRK---------KSKKSPSSES 257

  Fly   256 EDREEGELHPLVTITKIDPNEIPEV-SNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSRN 319
            | .|..:..|..|:.   |.|||.: .|:||||....|:.|:|.         :.::::|:|..|
Mouse   258 E-AENVDAQPQSTVR---PEEIPPIPENRFLMRKSPPKADDKER---------KNRERERERECN 309

  Fly   320 NFGWSKKQAPPTS------------RSGRIVKGRGVFRFRTPSRSRS-----RSTTPPHWKHAQK 367
                     ||.|            ||||.:||||..|:||||||||     ||.|||||:...:
Mouse   310 ---------PPNSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQ 365

  Fly   368 RTIKL-------------SDLERIEE--ESKMREEEMKRREHERKRRHEEATKNPKQSFFELSHA 417
            |..::             |:|..|:|  .|.:|.:|.|..:|    ||...:.|
Mouse   366 RAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDH----RHMSESPN----------- 415

  Fly   418 STYGGKITPDRFSPEHKAKSKDTADRGKAKEREKAGEKDKARDVTPVKRRKSMDMNALDYEQQTE 482
                .|:..::.:.:||::||:                   ||:    ||.|
Mouse   416 ----RKVEKEKKAKDHKSESKE-------------------RDI----RRNS------------- 440

  Fly   483 SEVESEDE-EQLKVKPPSKQDIRVEPSTSKDRNAKRDERKPTEEKAKPKRSRSRSPRRQSPARRQ 546
               |.:|: .:.|||...|...|   |.||:| :|..||.....:.:.||.||||..|.....::
Mouse   441 ---EKDDKYNKNKVKKRGKSKSR---SKSKER-SKSKERDSKHSRHEDKRVRSRSKERDHETTKE 498

  Fly   547 QRSPARRPGQNYNQNQNQNQNQNQNQNQLNRGNRRNPFADRDRRRRSRSQDNEYRNRYPLSPIRG 611
            :..|....|::..::::: :|..|.:::.|. :..:...::|||.:|||::.:..
Mouse   499 KEKPLDPKGKDQERSRSK-ENSKQVESKSNE-HDHSKSKEKDRRAQSRSRERDLT---------- 551

  Fly   612 RGSPSGDRRRQQRSRSQNRRQDSPSQRRQLSPGRKRQDSPSKKRPNSTERKWRDSPERKRDDSHD 676
            :...|.:.|.::||||::|      .||..|....|..|.||:.....|:::|   .|.|..|.|
Mouse   552 KSKHSYNSRTRERSRSRDR------SRRVRSRSHDRDRSRSKEYHRYREQEYR---RRGRSRSRD 607

  Fly   677 RKREASPNWKRDDSPARKRKDSANRKREDSQDKKIQDSKRQEDSAGKKREDSPSKKRKDSDKKRQ 741
            |:   :|...|.....|:|:||.:.:||:||.:.....:.||..:..::|:|..:||..|..:..
Mouse   608 RR---TPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRKENSEGEKRTYSKSRDH 669

  Fly   742 DSPVKRQESPGRKRQDSPERKRRDSPDRRRKDSPARRRQESSGRRRQDSDGRRRRESSGNRRSRS 806
            :|....:|    |:.|     |..||..:.|.|......:||..:.|:.:..|......|::|:.
Mouse   670 NSSSNNRE----KKAD-----REQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQKSKG 725

  Fly   807 RGRWHSSSRSR------SPSTSRSR 825
            :...|...:::      ||.|...:
Mouse   726 QENDHVHDKNKKCDHESSPGTDEDK 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	114/166 (69%)
		SH3-RhoG_link	635..>718	CDD:293215	24/82 (29%)
Ppig	NP_001074555.1	cyclophilin	8..175	CDD:412213	114/166 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..752		179/695 (26%)
		PTZ00121	<401..750	CDD:173412	105/443 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	231	1.000	Domainoid score	I2422
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	417	1.000	Inparanoid score	I1798
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		otm42698
orthoMCL	1	0.900	-	-		OOG6_105724
Panther	1	1.100	-	-	LDO	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5641
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.820