DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and cyn-9

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_497745.1	Gene:	cyn-9 / 175471	WormBaseID:	WBGene00000885	Length:	309	Species:	Caenorhabditis elegans

Alignment Length:	380	Identity:	144/380 - (37%)
Similarity:	192/380 - (50%)	Gaps:	73/380 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVV 74
            |...|.|.|||:....:|||...||.:.||||.||||||||||.|.......:|.||...|||:|
Worm     2 AAEKRVFLDISVDENLIGRIEIRLFVEDAPKTCENFRALCTGEVGMTPNNKARLHYKQNEFHRIV 66

  Fly    75 KDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHL 139
            |.||:|.||.:.|:|.||.||||..|:||.|:.||.||:||||||:|.|:|.|||||||..|||.
Worm    67 KKFMIQGGDITEGDGRGGFSIYGRYFDDEKFKLKHSRPYLLSMANKGPNSNSSQFFITTAAAPHC 131

  Fly   140 DNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDS 204
            :..|||||:|:.||.:|..::.|.||..|:||....|:||||||:  |.|..|..:..:.|.|:.
Worm   132 NGKHVVFGEVVKGQNVVDYIDNLAVDDKSKPLAKVLISNCGELVK--KKKPLKTDEELAAALEEK 194

  Fly   205 NSEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGELHPLVTI 269
            |:...:.|   :.|..|....|.|        |||.     ||:..   :|:.||
Worm   195 NNNARDNE---IPKCPKSWLYRDD--------DNEK-----KHEMR---NDKRRE---------- 230

  Fly   270 TKIDPNEIPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSRNNFGWSKKQAPPTSRS 334
                            .|:.||:|              |..:::||..:.|.|.|.:..|....:
Worm   231 ----------------YRSRRSRS--------------RSHEKNRDYKKENRGDSSRSQPRRDEN 265

  Fly   335 GRIVKGRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLSDLERIEEESKMREEEM 389
            |..|:|||..|||     |.||.||.||:       :.:..:.:.:..|..||::
Worm   266 GITVRGRGGVRFR-----RERSATPEHWR-------RNAPTKWVHDSHKHPEEDL 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	90/166 (54%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
cyn-9	NP_497745.1	cyclophilin	6..172	CDD:294131	90/165 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		otm14615
orthoMCL	1	0.900	-	-		OOG6_105724
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720