Protein Alignment Moca-cyp and sig-7

DIOPT Version :10

• Sequence 1: NP_733246.1
• Gene: Moca-cyp / 43374
• FlyBaseID: FBgn0039581
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_492343.2
• Gene: sig-7 / 172664
• WormBaseID: WBGene00000890
• Length: 427
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 143/616 - (23%)
• Similarity: 221/616 - (35%)
• Gaps: 214/616 - (34%)

  Fly    26 MGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGT 90
            :|.::.:||....|:.:.||..||           ||..|....||.:.::::.|.|| ..|.|.
 Worm     9 LGDLIIDLFVKERPRCSLNFLKLC-----------KKKYYNLNQFHSIERNYVAQTGD-PTGTGK 61

  Fly    91 GGESIY-------GGTFEDESFEK-KHDRPFLLSMANRGKNTNGSQFFITT-QPAPHLDNIHVVF 146
            ||||:|       |..||.|...| :|.|..::|..|.|.|..|||||||. :...:||:.|.:|
 Worm    62 GGESVYSDMYGEQGRYFEREDLPKMRHTRMGIVSFVNNGDNMLGSQFFITLGENLDYLDDQHTIF 126

  Fly   147 GQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSNSEESEA 211
            |||..|.|.:.:|.....|.|:||.:|..|::                    |...|...:|
 Worm   127 GQVTEGLETLEKLNEQLADTNNRPFKDIRISH--------------------TIVLDDPFDE--- 168

  Fly   212 EAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGELHPLVTITKIDPNE 276
            :|::               |......:.|.....|.||...|:.||.:||:             .
 Worm   169 DARI---------------SFPPRSPSPTYEMLVKTDQIALDEKEDEDEGK-------------T 205

  Fly   277 IPEVSNKFLMR--AERSKSLDREERGARGQDRDRGKDQDRDRSRNNFGWSKKQAPPTSRSGRIVK 339
            ..|::.:...|  ||:::.|:..           |..:|.|           :.||.:
 Worm   206 AEEIAEELQQREMAEQAQILEMV-----------GDLKDAD-----------EVPPEN------- 241

  Fly   340 GRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLS------DLERIEEESKMREEEMKRREHERKR 398
              .:|                        ..||:      |||.|..    |..::...|..|.|
 Worm   242 --VLF------------------------VCKLNPVTTDEDLEIIFS----RFGKINNCEIVRDR 276

  Fly   399 RHEEATKNPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTADRGKAKEREKAGEKDKARDVTP 463
            |..::.   :.:|.|..:                             ||..|:|..|
 Worm   277 RSGDSL---QYAFIEFDN-----------------------------AKSCEQAFFK-------- 301

  Fly   464 VKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSKQDIRVEPSTSKDRNAKRDERKPTEEKAK 528
                  || |.|..:::...:......:..|.||.|:|           :.|.:..:.| :.:.:
 Worm   302 ------MD-NVLIDDRRIHVDFSQSVSQNYKYKPKSQQ-----------QEAPKRRQSP-QRRPE 347

  Fly   529 PKRSRSRSPRRQSPARRQQRSPARRPGQNYNQNQNQNQNQNQNQNQLNRGNRRNPFADRDRRRRS 593
            .|||..|||   ||.||:..||.:...::|.:...:.:..:.|....:|..|.|   :||||...
 Worm   348 VKRSHQRSP---SPRRRRSPSPKKDKKRDYRREPARRRRSSDNHRDRDRSYRDN---NRDRRDNH 406

  Fly   594 RSQDNEYRNRYPLSPIRGRGSPSGDRRRQQR 624
            |..|.: |.|:..||         ||||.:|
 Worm   407 RDSDRD-RRRHDRSP---------DRRRDRR 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:469651	57/162 (35%)
		PRK12678	612..>804	CDD:237171	5/13 (38%)
sig-7	NP_492343.2	cyclophilin_RRM	4..169	CDD:238902	60/194 (31%)
		RRM_PPIL4	238..320	CDD:409681	25/165 (15%)