DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Moca-cyp and PPIH

DIOPT Version :9

Sequence 1:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_006338.1	Gene:	PPIH / 10465	HGNCID:	14651	Length:	177	Species:	Homo sapiens

Alignment Length:	178	Identity:	90/178 - (50%)
Similarity:	115/178 - (64%)	Gaps:	7/178 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DAGATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGE--KGFGLITGKKLQYKGVI 69
            ::....|..|||:|:||..:||:..|||.||.||||||||..||||  |     .|..:.|||..
Human     5 NSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRK-----DGVPIGYKGST 64

  Fly    70 FHRVVKDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQ 134
            ||||:||||:|.|||..|:|||..|||.|.|.||:|:.:|..|.||||||.|.:|||.|||||..
Human    65 FHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCS 129

  Fly   135 PAPHLDNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGEL 182
            ....||..|||||::|.|..::|::|.:|...|::|.....|:.|||:
Human   130 KCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	87/168 (52%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
PPIH	NP_006338.1	cyclophilin	8..177	CDD:412213	89/173 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820