Protein Alignment Gfat2 and gfat-2

DIOPT Version :10

• Sequence 1: NP_651617.1
• Gene: Gfat2 / 43373
• FlyBaseID: FBgn0039580
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_502156.1
• Gene: gfat-2 / 178067
• WormBaseID: WBGene00009035
• Length: 710
• Species: Caenorhabditis elegans
• Alignment Length: 720
• Identity: 436/720 - (60%)
• Similarity: 543/720 - (75%)
• Gaps: 47/720 - (6%)

  Fly     1 MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSGE--AQSIMLVKRTGKVK 63
            |||||||||:|.||.|.|::|:|:|||:|:|||||||.|||||..|..|  ...|.|:::.|||.
 Worm     1 MCGIFAYLNFLAPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNDIENPHSKIALLRKRGKVS 65

  Fly    64 VLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVVHNGIITNYKD 128
            ||.|.:.|.....:..:..:.|.|||||||||||.|.:|||||.||:::|.|:||||||||||::
 Worm    66 VLNDYIKENNEKLNMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDNNEFLVVHNGIITNYRE 130

  Fly   129 VKTLLEKRGYVFESDTDTEVIAKLVHHLWQQHPGYTFGELVEQAIQQLEGAFAIAFKSKHFPGEC 193
            :|..|||:|:.|||:|||||||||..|:..::|.::|.:|||..|||||||||:||||..|||:.
 Worm   131 IKEYLEKKGHKFESETDTEVIAKLTQHVHDRYPDFSFRQLVETVIQQLEGAFALAFKSSRFPGQL 195

  Fly   194 VASRRGSPLLVGIKAKTKLATDHIPILYAK-------------------------------AHRP 227
            ||||||||||||||:.:.|.|.|.|:.|:|                               ...|
 Worm   196 VASRRGSPLLVGIKSNSTLHTSHFPVSYSKGRCFMSNNATHLREETSFVETPNNILDLSIAVRNP 260

  Fly   228 HGQPQQQAYQLLPPGDCNAEFQPLERK--EVEYFFASDASAVIEHTNRVIYLEDDDVAAVKSDGT 290
            .|..:      ||  |.|:..:|.:..  |||||.||||:|:||||.:|::|||||||.|: ||:
 Worm   261 SGSAK------LP--DNNSTTRPFDSTDFEVEYFIASDAAAIIEHTKQVLFLEDDDVAFVE-DGS 316

  Fly   291 LSIHRLNKSSDD-PHAREIITLKMEIQQIMKGNYDYFMLKEIFEQPESVVNTMRGRMRFDTQTVV 354
            |:|||:::.:|. ...||:..|::|||:||||:|..||.|||||||||||||||||: ..:..||
 Worm   317 LTIHRISRHADSGEQKREVQLLELEIQEIMKGSYKTFMQKEIFEQPESVVNTMRGRV-LPSGQVV 380

  Fly   355 LGGIKEYIPEIKRCRRLMLIACGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVC 419
            |||:|||:|.|||||||:::|||||||||:|.||:||||:||||:||||||||||.|||||:|||
 Worm   381 LGGLKEYLPAIKRCRRLIMVACGTSYHSAIACRQVLEELSELPVVVELASDFLDRETPIFRNDVC 445

  Fly   420 FFISQSGETADTLMALRYCKQRGALIVGVTNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQF 484
            .|||||||||||||||||||.||||.:||||||||||.||||||:|||||||||||||||||||.
 Worm   446 LFISQSGETADTLMALRYCKPRGALTIGVTNTVGSSIGRESHCGIHINAGPEIGVASTKAYTSQI 510

  Fly   485 ISLVMFALVMSEDRLSLQQRRLEIIDGLSQLDEHIRTVLKLNSQVQQLAKELYEHKSLLIMGRGF 549
            :||::|||.:||||:|..:||.||||.|:.|...||.||.|:.||.::|:::|:.|||||||||.
 Worm   511 VSLLLFALTISEDRISKMKRRAEIIDALNNLPILIRDVLDLDDQVLKIAEQIYKDKSLLIMGRGL 575

  Fly   550 NFATCLEGALKVKELTYMHSEGILAGELKHGPLALVDKEMPVLMIVLRDPVYTKCMNALQQVTSR 614
            |||||||||||:|||:|||.|||::|||||||||:||:.:.:.|:|..|.||.|.:||||||.:|
 Worm   576 NFATCLEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDHVYKKSLNALQQVVAR 640

  Fly   615 KGRPILICEEGDNET-MSFSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGCDVDCPRNLAK 678
            ||.||:|.:....|: ::.....|::||||||:|.:||||||||||||||.|.|.:||.||||||
 Worm   641 KGAPIIIADSSVPESDLAGMKHVLRVPRTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAK 705

  Fly   679 SVTVE 683
            |||||
 Worm   706 SVTVE 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gfat2	NP_651617.1	PLN02981	1..683	CDD:215531	434/718 (60%)
gfat-2	NP_502156.1	PLN02981	1..710	CDD:215531	434/718 (60%)