Protein Alignment Gfat2 and gfat-1

DIOPT Version :10

• Sequence 1: NP_651617.1
• Gene: Gfat2 / 43373
• FlyBaseID: FBgn0039580
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001369886.1
• Gene: gfat-1 / 174778
• WormBaseID: WBGene00008546
• Length: 725
• Species: Caenorhabditis elegans
• Alignment Length: 730
• Identity: 436/730 - (59%)
• Similarity: 550/730 - (75%)
• Gaps: 52/730 - (7%)

  Fly     1 MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSGEA--QSIMLVKRTGKVK 63
            |||||||||:||||.|.|::|:|:|||:|:|||||||.|||||..|..|:  .|:.|:::.|||.
 Worm     1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRKAGKVS 65

  Fly    64 VLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVVHNGIITNYKD 128
            ||.|.:.|.....|..:..:.|.|||||||||||.|.:|||||.||::.|.|:||||||||||::
 Worm    66 VLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVVHNGIITNYRE 130

  Fly   129 VKTLLEKRGYVFESDTDTEVIAKLVHHLWQQHPGYTFGELVEQAIQQLEGAFAIAFKSKHFPGEC 193
            :|..|||:|:.|||:|||||||||..|:..::|.::|.:|||..|||||||||:||||..|||:.
 Worm   131 IKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEGAFALAFKSSRFPGQL 195

  Fly   194 VASRRGSPLLVGIKAKTKLATDHIPILYAK-------------------AHRPHGQPQQQAYQL- 238
            ||||||||||||||:.::|.|:|.|:.::|                   .|..|.:.:....:.
 Worm   196 VASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGRRFMSNHATHLRDETSFVETP 260

  Fly   239 ------------------LPPGDCNAEFQPLERK--EVEYFFASDASAVIEHTNRVIYLEDDDVA 283
                              :...|.....:|.:..  |||||.||||:|:||||.:|::|||||||
 Worm   261 NNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEYFVASDAAAIIEHTKQVLFLEDDDVA 325

  Fly   284 AVKSDGTLSIHRLNKSSDD-PHAREIITLKMEIQQIMKGNYDYFMLKEIFEQPESVVNTMRGRMR 347
            .|: ||.|:|||:::.:|: ...||:..|:||:|:||||::..:|.|||||||:|||||||||:
 Worm   326 FVE-DGALTIHRISRHADNGEQKREVKLLEMELQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV- 388

  Fly   348 FDTQTVVLGGIKEYIPEIKRCRRLMLIACGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTP 412
            ..:..|||||||||:|:|||||||:::|||||||||:|.||:||||:||||:||||||||||.||
 Worm   389 LPSGQVVLGGIKEYLPDIKRCRRLIMVACGTSYHSAIACRQILEELSELPVVVELASDFLDRETP 453

  Fly   413 IFRDDVCFFISQSGETADTLMALRYCKQRGALIVGVTNTVGSSICRESHCGVHINAGPEIGVAST 477
            |||||||.||||||||||||:||||||.||||.:|||||||||||||||||:|||||||||||||
 Worm   454 IFRDDVCLFISQSGETADTLLALRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVAST 518

  Fly   478 KAYTSQFISLVMFALVMSEDRLSLQQRRLEIIDGLSQLDEHIRTVLKLNSQVQQLAKELYEHKSL 542
            ||||||.:||:||||.:|:||:|:.:||.||||.|:.|.|.||.||:|:.:|..:||::|:.|||
 Worm   519 KAYTSQILSLLMFALTLSDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSL 583

  Fly   543 LIMGRGFNFATCLEGALKVKELTYMHSEGILAGELKHGPLALVDKEMPVLMIVLRDPVYTKCMNA 607
            ||||||.|||||||||||:|||:|||.|||::|||||||||:||:.:.:.|:|..|.||.|.:||
 Worm   584 LIMGRGLNFATCLEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNA 648

  Fly   608 LQQVTSRKGRPILICE----EGDNETMSFSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGC 668
            ||||.:|||.||:|.:    |||...|.   ..|::|:||||:|.:||||||||||||||.|.|.
 Worm   649 LQQVVARKGAPIIIADCTVPEGDLAGMK---HILRVPKTVDCVQNILTVIPLQLLSYHIAELNGA 710

  Fly   669 DVDCPRNLAKSVTVE 683
            :||.|||||||||||
 Worm   711 NVDRPRNLAKSVTVE 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gfat2	NP_651617.1	PLN02981	1..683	CDD:215531	434/728 (60%)
gfat-1	NP_001369886.1	PLN02981	1..725	CDD:215531	434/728 (60%)