Protein Alignment CG12516 and Aldh1l2

DIOPT Version :10

• Sequence 1: NP_651615.2
• Gene: CG12516 / 43370
• FlyBaseID: FBgn0039577
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_705771.2
• Gene: Aldh1l2 / 216188
• MGIID: 2444680
• Length: 923
• Species: Mus musculus
• Alignment Length: 221
• Identity: 49/221 - (22%)
• Similarity: 79/221 - (35%)
• Gaps: 71/221 - (32%)

  Fly    57 SEAVSESEKEVIEVSEEPKE--EEVKYAW-----NAPCMMVIFEDGDVNCALHHLVESLQDPFAL 114
            |:..|..|..|:|::.|..:  |.:|..|     |.|                 ::|...|.|..
Mouse   324 SQYFSAGETSVVELTAEELKVAETIKVIWARILSNTP-----------------VIEDSTDFFKS 371

  Fly   115 DAVAVILVQEALAEEIENRVKILMKPLDARVANHPCYKRT-----LMKI-------DELRPKTII 167
            .|.::.:|:  |.|||......|      ::.|...|..|     :.|:       ||.....:
Mouse   372 GASSMDVVR--LVEEIRQSCGGL------QLQNEDVYMATKFGDFIQKVVRRLRGEDEEAEMVV- 427

  Fly   168 GPSDRVLPDATPIMVRDIPHK-FLG-------DGPTGIITMHIFRTPFEATQIYRKEYPLPIASV 224
               |.|..:...:.|: ||:: |:.       ||.|     :....|.:.|.|.|..|    ||:
Mouse   428 ---DYVSKEVNGMTVK-IPYQCFINGQFVDAEDGET-----YATVNPTDGTTICRVSY----ASL 479

  Fly   225 SIWNERVSSVYDVI-----GMMNLLD 245
            :..:..|::..|..     |.||..|
Mouse   480 ADVDRAVAAAKDAFENGEWGRMNARD 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12516	NP_651615.2	DUF1487	82..298	CDD:254173	41/194 (21%)
Aldh1l2	NP_705771.2	Hydrolase domain. /evidence=ECO:0000250|UniProtKB:P28037	23..331		2/6 (33%)
		FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731	1/2 (50%)
		AcpP	344..417	CDD:440006	19/97 (20%)
		ALDH_F1L_FTFDH	438..923	CDD:143458	20/78 (26%)
		Aldehyde dehydrogenase domain. /evidence=ECO:0000250|UniProtKB:P28037	438..923		20/78 (26%)