DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and UBP1A

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_849806.1	Gene:	UBP1A / 841846	AraportID:	AT1G54080	Length:	430	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	143/510 - (28%)
Similarity:	205/510 - (40%)	Gaps:	169/510 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 QQQHPQQQQHDLHM-------QHPLTPSEDCKPLLHAKSVPPPPQPPPMLTHFQAMMQPPPLPPS 202
            |||..|||||...|       ||         |.|:...|..|||..|:              ||
plant     9 QQQQQQQQQHQQAMIQQAMMQQH---------PSLYHPGVMAPPQMEPL--------------PS 50

  Fly   203 PMMPPQSFGCPLPSRT-------------------PATPPLPGTYRVQSLKSA---------AAA 239
            ..:|| .|. |...|:                   .:|.|:.....::..||:         ..|
plant    51 GNLPP-GFD-PTTCRSVYAGNIHTQVTEILLQEIFASTGPIESCKLIRKDKSSYGFVHYFDRRCA 113

  Fly   240 AVSAYQRNGKLPRNLPALRAMEMALRTN-SFATPPAPHSLPLPPPHAARTEGGGQDMEDSDEEME 303
            :::....||:        ......::.| ::||                    || .||:.
plant   114 SMAIMTLNGR--------HIFGQPMKVNWAYAT--------------------GQ-REDTS---- 145

  Fly   304 YMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEIS----DCRVVRDPQTLKSKGYGFVSFIKKS 364
                  ..|:|||||||.|:....|.::|:.|...|    |.||:.|.:|.:|:|:|||||..:.
plant   146 ------SHFNIFVGDLSPEVTDAALFDSFSAFNSCSSYYRDARVMWDQKTGRSRGFGFVSFRNQQ 204

  Fly   365 EAESAITAMNGQWLGSRSIRTNWATR-------KPPASKENIKPLTFD------EVYNQSSPSN- 415
            :|::||..|||:|:.||.||.||||:       |..:..:::..||..      |:.|:.:|.|
plant   205 DAQTAINEMNGKWVSSRQIRCNWATKGATFGEDKHSSDGKSVVELTNGSSEDGRELSNEDAPENN 269

  Fly   416 ---CTVYVGGVNSALTALSEEVLQKTFAPYGA--IQEIRVFKDKGYAFVRFSTKEAATHAI-VGV 474
               .|||||.::..:|.|.   |.:.|...||  |:|:||.:|||:.|||::|.:.|..|| :|
plant   270 PQFTTVYVGNLSPEVTQLD---LHRLFYTLGAGVIEEVRVQRDKGFGFVRYNTHDEAALAIQMG- 330

  Fly   475 HNTEINAQP------VKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAA--AAAYGQ 531
                 ||||      ::||||       |..|.:..|.|.....|   |..|.:.:|  ..||.:
plant   331 -----NAQPFLFSRQIRCSWG-------NKPTPSGTASNPLPPPA---PASVPSLSAMDLLAYER 380

  Fly   532 QLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQ 586
            |||..    ...|....|...|......|...||:.:              ||||
plant   381 QLALA----KMHPQAQHSLRQAGLGVNVAGGTAAMYD--------------GGYQ 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	35/77 (45%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	34/83 (41%)
UBP1A	NP_849806.1	RRM1_TIA1_like	65..135	CDD:240798	8/77 (10%)
		ELAV_HUD_SF	74..331	CDD:273741	87/304 (29%)
		RRM2_PUB1	149..227	CDD:241063	35/77 (45%)
		RRM3_TIA1_like	273..348	CDD:240800	34/90 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I3083
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I1394
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1066369at2759
OrthoFinder	1	1.000	-	-		FOG0000924
OrthoInspector	1	1.000	-	-		mtm1150
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X831
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970