DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and Trnau1ap

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_082201.2	Gene:	Trnau1ap / 71787	MGIID:	1919037	Length:	287	Species:	Mus musculus

Alignment Length:	193	Identity:	56/193 - (29%)
Similarity:	83/193 - (43%)	Gaps:	48/193 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 LPGTYRVQSLKSAAAAAVSAYQRNGK-LPRNLPALRAMEMALRTNSFATPPAPHSLPLPPPHAAR 287
            :|..|........|.|....::.||| ||...||.|     .:.| :||
Mouse    43 IPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKR-----FKLN-YAT---------------- 85

  Fly   288 TEGGGQDMEDSDEEMEYMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCR---VVRDPQT 349
               .|:..::|.|           :.:|||||:.:::...|.|.|...  ...||   ||.|| |
Mouse    86 ---YGKQPDNSPE-----------YSLFVGDLTPDVDDGMLYEFFVKV--YPSCRGGKVVLDP-T 133

  Fly   350 LKSKGYGFVSFIKKSEAESAITAMNGQ-WLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQS 411
            ..|||||||.|..:.|.:.|:|...|. .||.:.:|.:.|.  |.||:  :||:.:.::|:.|
Mouse   134 GVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAI--PKASR--VKPVEYSQMYSYS 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	30/77 (39%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800
Trnau1ap	NP_082201.2	RRM1_SECp43	4..87	CDD:241054	15/68 (22%)
Trnau1ap	NP_082201.2	RRM2_SECp43	95..176	CDD:241056	32/96 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910