DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and Cstf2

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	XP_038955991.1	Gene:	Cstf2 / 683927	RGDID:	1596566	Length:	624	Species:	Rattus norvegicus

Alignment Length:	386	Identity:	97/386 - (25%)
Similarity:	147/386 - (38%)	Gaps:	121/386 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWL 378
            :|||::..|...:||::.|:..|.:...|:|.|.:|.|.|||||..:..:..|.||:..:||:..
  Rat    18 VFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREF 82

  Fly   379 GSRSIRT-NWATRKPPASKENIKPL-----TFDEVYNQS-SPSNCTVYVGGVNSALTALSEEVL- 435
            ..|::|. |.|:.|   :||.:|.|     ..:..|.:| ||.:..   ..::.|:.:|..|.:
  Rat    83 SGRALRVDNAASEK---NKEELKSLGTGAPVIESPYGESISPEDAP---ESISKAVASLPPEQMF 141

  Fly   436 ----QKTFAPYGAIQEIRVF----KDKGYAFVRFSTKEAATHAIVGVHNTEI------------- 479
                |.......:.||.|..    ....||.::       ...::.:.:.||
  Rat   142 ELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQ-------AQVVMRIVDPEIALKILHRQTNIPT 199

  Fly   480 ----NAQPVKCSWGKESGDPN-----------NAQTIATQALNSA-----AAAAAGFPYGVGAAA 524
                |.|||..: |..|| ||           .||:::...:|.|     |:...|.|..|..||
  Rat   200 LISGNPQPVHVA-GPGSG-PNVSMNQQNPQAPQAQSLSGMHVNGAPPMMQASMPGGVPAPVQMAA 262

  Fly   525 AAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQG-----YHFGQYGG 584
            |.|..|                |.|.|      ||....|.|      |:||     ...|| |.
  Rat   263 AVAGPG----------------PGSLA------PAGVMQAQV------GMQGAGPVPMERGQ-GT 298

  Fly   585 YQQGYMGMG-------VQIPATW------QGVTQAQISPAQQLATGVAGTAI-----PQAA 627
            .|...:|..       ||...||      :|.|     |:..::.|:.|.|:     |:||
  Rat   299 LQHSPVGPAGPASIERVQGQRTWMIWASVRGST-----PSLLVSGGLDGIAVLPMQDPRAA 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	25/73 (34%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	16/100 (16%)
Cstf2	XP_038955991.1	RRM_CSTF2_CSTF2T	10..94	CDD:410072	26/75 (35%)
		CSTF2_hinge	112..191	CDD:405077	15/88 (17%)
		PRK14718	<444..>501	CDD:173181
		CSTF_C	580..620	CDD:405061
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910