DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and LOC681410

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	XP_003751688.1	Gene:	LOC681410 / 681410	RGDID:	1595414	Length:	307	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	73/290 - (25%)
Similarity:	116/290 - (40%)	Gaps:	71/290 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWL 378
            :|:|.|:.:.....||..|..||.::||.||.:|||.:|:.:|||::....||::|:.|
  Rat     9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAA------ 67

  Fly   379 GSRSIRTNWATRKPPASKE-NIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPY 442
            ...::..|....|...|:| :.:|....:|..        ::|||:..   .::|..|.:.|:.:
  Rat    68 SPHAVDGNTVELKRAVSREDSARPGAHAKVKK--------LFVGGLKG---DVAEGDLIEHFSQF 121

  Fly   443 GAIQEIRVFKDK------GYAFVRFSTKEAATH-AIVGVHNTEINAQPVKCSWGKESGDPNNAQT 500
            ||:::..:..||      |:.||.|.:.:||.. |:|..|..:.:...||.:..||.
  Rat   122 GAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKED-------- 178

  Fly   501 IATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAA 565
                       ..||   |.||.||....|......|                    ........
  Rat   179 -----------IHAG---GGGARAARGGRGGGRGRGG--------------------GGGGGGGR 209

  Fly   566 VQNQFLQGIQGYH--FGQYGGYQQGYMGMG 593
            .||...:|..|.:  :|.||||  |..|.|
  Rat   210 DQNGLAKGGGGGYNSYGGYGGY--GAYGGG 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	23/72 (32%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	21/81 (26%)
LOC681410	XP_003751688.1	RRM1_hnRNPA0	5..83	CDD:240772	25/79 (32%)
		RRM2_hnRNPA0	99..178	CDD:241023	22/89 (25%)
		HnRNPA1	250..>269	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000